Intradermal and transdermal drug delivery using microneedles–Fabrication, performance evaluation and application to lymphatic delivery AH Sabri, Y Kim, M Marlow, DJ Scurr, J Segal, AK Banga, L Kagan, ... Advanced drug delivery reviews 153, 195-215, 2020 | 136 | 2020 |
The role of the lymphatic system in subcutaneous absorption of macromolecules in the rat model L Kagan, P Gershkovich, A Mendelman, S Amsili, N Ezov, A Hoffman European journal of pharmaceutics and biopharmaceutics 67 (3), 759-765, 2007 | 109 | 2007 |
Subcutaneous absorption of monoclonal antibodies: role of dose, site of injection, and injection volume on rituximab pharmacokinetics in rats L Kagan, MR Turner, SV Balu-Iyer, DE Mager Pharmaceutical research 29, 490-499, 2012 | 107 | 2012 |
Gastroretentive accordion pill: enhancement of riboflavin bioavailability in humans L Kagan, N Lapidot, M Afargan, D Kirmayer, E Moor, Y Mardor, ... Journal of controlled release 113 (3), 208-215, 2006 | 92 | 2006 |
Systems for region selective drug delivery in the gastrointestinal tract: biopharmaceutical considerations L Kagan, A Hoffman Expert Opinion on Drug Delivery 5 (6), 681-692, 2008 | 89 | 2008 |
High-dose bupivacaine remotely loaded into multivesicular liposomes demonstrates slow drug release without systemic toxic plasma concentrations after subcutaneous … EM Davidson, Y Barenholz, R Cohen, S Haroutiunian, L Kagan, ... Anesthesia & Analgesia 110 (4), 1018-1023, 2010 | 86 | 2010 |
Quantitative analysis of lab-to-lab variability in Caco-2 permeability assays JB Lee, A Zgair, DA Taha, X Zang, L Kagan, TH Kim, MG Kim, H Yun, ... European Journal of Pharmaceutics and Biopharmaceutics 114, 38-42, 2017 | 82 | 2017 |
Pharmacokinetic modeling of the subcutaneous absorption of therapeutic proteins L Kagan Drug Metabolism and Disposition 42 (11), 1890-1905, 2014 | 82 | 2014 |
Selection of drug candidates for gastroretentive dosage forms: pharmacokinetics following continuous intragastric mode of administration in a rat model L Kagan, A Hoffman European journal of pharmaceutics and biopharmaceutics 69 (1), 238-246, 2008 | 70 | 2008 |
Mechanisms of subcutaneous absorption of rituximab in rats L Kagan, DE Mager Drug metabolism and disposition 41 (1), 248-255, 2013 | 58 | 2013 |
Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system JB Lee, A Zgair, J Malec, TH Kim, MG Kim, J Ali, C Qin, W Feng, M Chiang, ... Journal of controlled release 286, 10-19, 2018 | 54 | 2018 |
Interspecies scaling of receptor-mediated pharmacokinetics and pharmacodynamics of type I interferons L Kagan, AK Abraham, JM Harrold, DE Mager Pharmaceutical research 27, 920-932, 2010 | 49 | 2010 |
Role of p-glycoprotein in region-specific gastrointestinal absorption of talinolol in rats L Kagan, T Dreifinger, DE Mager, A Hoffman Drug Metabolism and Disposition 38 (9), 1560-1566, 2010 | 45 | 2010 |
Dual physiologically based pharmacokinetic model of liposomal and nonliposomal amphotericin B disposition L Kagan, P Gershkovich, KM Wasan, DE Mager Pharmaceutical research 31, 35-45, 2014 | 42 | 2014 |
Cardiac glycoside cerberin exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition MS Hossan, ZY Chan, HM Collins, FN Shipton, MS Butler, M Rahmatullah, ... Cancer letters 453, 57-73, 2019 | 41 | 2019 |
Interspecies modeling and prediction of human exenatide pharmacokinetics T Chen, DE Mager, L Kagan Pharmaceutical research 30, 751-760, 2013 | 41 | 2013 |
Physiologically based pharmacokinetic model of amphotericin B disposition in rats following administration of deoxycholate formulation (Fungizone®): pooled analysis of … L Kagan, P Gershkovich, KM Wasan, DE Mager The AAPS journal 13, 255-264, 2011 | 38 | 2011 |
Somatosensory predictors of response to pregabalin in painful chemotherapy-induced peripheral neuropathy: a randomized, placebo-controlled, crossover study A Hincker, K Frey, L Rao, N Wagner-Johnston, AB Abdallah, B Tan, ... Pain 160 (8), 1835-1846, 2019 | 32 | 2019 |
Prevention of paclitaxel-induced neuropathy by formulation approach X Zang, JB Lee, K Deshpande, OB Garbuzenko, T Minko, L Kagan Journal of controlled release 303, 109-116, 2019 | 32 | 2019 |
Interspecies pharmacokinetic modeling of subcutaneous absorption of rituximab in mice and rats L Kagan, J Zhao, DE Mager Pharmaceutical research 31, 3265-3273, 2014 | 29 | 2014 |