| Pathways to tamoxifen resistance RB Riggins, RS Schrecengost, MS Guerrero, AH Bouton Cancer letters 256 (1), 1-24, 2007 | 349 | 2007 |
| Functions of the adapter protein Cas: signal convergence and the determination of cellular responses AH Bouton, RB Riggins, PJ Bruce-Staskal Oncogene 20 (44), 6448-6458, 2001 | 264 | 2001 |
| Human X‐box binding protein‐1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines BP Gomez, RB Riggins, AN Shajahan, U Klimach, A Wang, AC Crawford, ... The FASEB Journal 21 (14), 4013-4027, 2007 | 226 | 2007 |
| Interferon regulatory factor-1 (IRF-1) exhibits tumor suppressor activities in breast cancer associated with caspase activation and induction of apoptosis KB Bouker, TC Skaar, RB Riggins, DS Harburger, DR Fernandez, A Zwart, ... Carcinogenesis 26 (9), 1527-1535, 2005 | 158 | 2005 |
| The nuclear factor κB inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)–induced apoptosis in antiestrogen-resistant breast cancer cells RB Riggins, A Zwart, R Nehra, R Clarke Molecular cancer therapeutics 4 (1), 33-41, 2005 | 155 | 2005 |
| Differential dependency network analysis to identify condition-specific topological changes in biological networks B Zhang, H Li, RB Riggins, M Zhan, J Xuan, Z Zhang, EP Hoffman, ... Bioinformatics 25 (4), 526-532, 2009 | 139 | 2009 |
| ERRγ mediates tamoxifen resistance in novel models of invasive lobular breast cancer RB Riggins, JPJ Lan, U Klimach, A Zwart, LR Cavalli, BR Haddad, L Chen, ... Cancer research 68 (21), 8908-8917, 2008 | 130 | 2008 |
| Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and … RB Riggins, KS Thomas, HQ Ta, J Wen, RJ Davis, NR Schuh, ... Cancer research 66 (14), 7007-7015, 2006 | 124 | 2006 |
| Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer RB Riggins, AH Bouton, MC Liu, R Clarke Vitamins & Hormones 71, 201-237, 2005 | 113 | 2005 |
| BCL2 and CASP8 regulation by NF-κB differentially affect mitochondrial function and cell fate in antiestrogen-sensitive and-resistant breast cancer cells R Nehra, RB Riggins, AN Shajahan, A Zwart, AC Crawford, R Clarke The FASEB Journal 24 (6), 2040, 2010 | 109 | 2010 |
| Identifying cancer biomarkers by network-constrained support vector machines L Chen, J Xuan, RB Riggins, R Clarke, Y Wang BMC systems biology 5, 1-20, 2011 | 108 | 2011 |
| Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3 RB Riggins, LA Quilliam, AH Bouton Journal of Biological Chemistry 278 (30), 28264-28273, 2003 | 108 | 2003 |
| IFNγ restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-κB, BCL2 family members, and signaling to caspase-dependent apoptosis Y Ning, RB Riggins, JE Mulla, H Chung, A Zwart, R Clarke Molecular cancer therapeutics 9 (5), 1274-1285, 2010 | 101* | 2010 |
| NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer R Hu, A Warri, L Jin, A Zwart, RB Riggins, HB Fang, R Clarke Molecular and cellular biology, 2015 | 94 | 2015 |
| The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer HR Fernandez, SM Gadre, M Tan, GT Graham, R Mosaoa, MS Ongkeko, ... Cell Death & Differentiation 25 (7), 1239-1258, 2018 | 92 | 2018 |
| Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis AC Crawford, RB Riggins, AN Shajahan, A Zwart, R Clarke PloS one 5 (1), e8604, 2010 | 89 | 2010 |
| The role of XBP-1 in tumorigenicity AN Shajahan, RB Riggins, R Clarke Drug news & perspectives 22 (5), 241, 2009 | 87 | 2009 |
| Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells R Clarke, AN Shajahan, RB Riggins, Y Cho, A Crawford, J Xuan, Y Wang, ... The Journal of steroid biochemistry and molecular biology 114 (1-2), 8-20, 2009 | 86 | 2009 |
| Interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (Faslodex, Fulvestrant) KB Bouker, TC Skaar, DR Fernandez, KA O’Brien, RB Riggins, D Cao, ... Cancer research 64 (11), 4030-4039, 2004 | 85 | 2004 |
| Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer T Du, MJ Sikora, KM Levine, N Tasdemir, RB Riggins, SG Wendell, ... Breast Cancer Research 20, 1-15, 2018 | 83 | 2018 |
