Stefan N. Constantinescu
Stefan N. Constantinescu
Professeur, Université catholique de Louvain- de Duve Institute, Member, Ludwig Institute for Cancer Research
Adresă de e-mail confirmată pe bru.licr.org
Citat de
Citat de
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
C James, V Ugo, JP Le Couédic, J Staerk, F Delhommeau, C Lacout, ...
nature 434 (7037), 1144-1148, 2005
Development of human protein reference database as an initial platform for approaching systems biology in humans
S Peri, JD Navarro, R Amanchy, TZ Kristiansen, CK Jonnalagadda, ...
Genome research 13 (10), 2363-2371, 2003
Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line: pathways that are shared with and distinct from IL-10
D Lejeune, L Dumoutier, S Constantinescu, W Kruijer, JJ Schuringa, ...
Journal of Biological Chemistry 277 (37), 33676-33682, 2002
JAK/STAT signaling in hematological malignancies
W Vainchenker, SN Constantinescu
Oncogene 32 (21), 2601-2613, 2013
New mutations and pathogenesis of myeloproliferative neoplasms
W Vainchenker, F Delhommeau, SN Constantinescu, OA Bernard
Blood, The Journal of the American Society of Hematology 118 (7), 1723-1735, 2011
NetPath: a public resource of curated signal transduction pathways
K Kandasamy, SS Mohan, R Raju, S Keerthikumar, GSS Kumar, ...
Genome biology 11 (1), 1-9, 2010
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia
E Flex, V Petrangeli, L Stella, S Chiaretti, T Hornakova, L Knoops, ...
The Journal of experimental medicine 205 (4), 751-758, 2008
Transforming growth factor β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
X Liu, Y Sun, SN Constantinescu, E Karam, RA Weinberg, HF Lodish
Proceedings of the National Academy of Sciences 94 (20), 10669-10674, 1997
The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor
LJ Huang, SN Constantinescu, HF Lodish
Molecular cell 8 (6), 1327-1338, 2001
Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants
I Chachoua, C Pecquet, M El-Khoury, H Nivarthi, RI Albu, C Marty, ...
Blood, The Journal of the American Society of Hematology 127 (10), 1325-1335, 2016
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
PS Woll, U Kjällquist, O Chowdhury, H Doolittle, DC Wedge, S Thongjuea, ...
Cancer cell 25 (6), 794-808, 2014
Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain
SN Constantinescu, T Keren, M Socolovsky, H Nam, YI Henis, HF Lodish
Proceedings of the National Academy of Sciences 98 (8), 4379-4384, 2001
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies
W Vainchenker, A Dusa, SN Constantinescu
Seminars in cell & developmental biology 19 (4), 385-393, 2008
The erythropoietin receptor: structure, activation and intracellular signal transduction
SN Constantinescu, S Ghaffari, HF Lodish
Trends in Endocrinology & Metabolism 10 (1), 18-23, 1999
Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms
JD Milosevic Feenstra, H Nivarthi, H Gisslinger, E Leroy, E Rumi, ...
Blood, The Journal of the American Society of Hematology 127 (3), 325-332, 2016
Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis
C Marty, C Pecquet, H Nivarthi, M El-Khoury, I Chachoua, M Tulliez, ...
Blood, The Journal of the American Society of Hematology 127 (10), 1317-1324, 2016
JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor
J Staerk, A Kallin, JB Demoulin, W Vainchenker, SN Constantinescu
Journal of Biological Chemistry 280 (51), 41893-41899, 2005
Cytokine receptor signal transduction and the control of hematopoietic cell development
SS Watowich, H Wu, M Socolovsky, U Klingmuller, SN Constantinescu, ...
Annual review of cell and developmental biology 12 (1), 91-128, 1996
Inhibitors of amyloid toxicity based on β-sheet packing of Aβ40 and Aβ42
T Sato, P Kienlen-Campard, M Ahmed, W Liu, H Li, JI Elliott, S Aimoto, ...
Biochemistry 45 (17), 5503-5516, 2006
Sistemul nu poate realiza operația în acest moment. Încercați din nou mai târziu.
Articole 1–20