Zan Chen
Zan Chen
Harvard Medical School
Verified email at
Cited by
Cited by
Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution
GCH Mo, B Ross, F Hertel, P Manna, X Yang, E Greenwald, C Booth, ...
Nature methods 14 (4), 427-434, 2017
Synthetic approaches to protein phosphorylation
Z Chen, PA Cole
Current opinion in chemical biology 28, 115-122, 2015
Akt kinase activation mechanisms revealed using protein semisynthesis
N Chu, AL Salguero, AZ Liu, Z Chen, DR Dempsey, SB Ficarro, ...
Cell 174 (4), 897-907. e14, 2018
A tunable brake for HECT ubiquitin ligases
Z Chen, H Jiang, W Xu, X Li, DR Dempsey, X Zhang, P Devreotes, ...
Molecular cell 66 (3), 345-357. e6, 2017
Enzyme-catalyzed expressed protein ligation
SH Henager, N Chu, Z Chen, D Bolduc, DR Dempsey, Y Hwang, J Wells, ...
Nature methods 13 (11), 925-927, 2016
Molecular features of phosphatase and tensin homolog (PTEN) regulation by C-terminal phosphorylation
Z Chen, DR Dempsey, SN Thomas, D Hayward, DM Bolduc, PA Cole
Journal of Biological Chemistry 291 (27), 14160-14169, 2016
Inhibition of the STAT3 signaling pathway is involved in the antitumor activity of cepharanthine in SaOS2 cells
Z Chen, C Huang, Y Yang, Y Ding, H Ou-Yang, Y Zhang, M Xu
Acta pharmacologica Sinica 33 (1), 101-108, 2012
Enzymatic analysis of PTEN ubiquitylation by WWP2 and NEDD4-1 E3 ligases
Z Chen, SN Thomas, DM Bolduc, X Jiang, X Zhang, C Wolberger, ...
Biochemistry 55 (26), 3658-3666, 2016
Site-Specific Protein Labeling with N-Hydroxysuccinimide-Esters and the Analysis of Ubiquitin Ligase Mechanisms
DR Dempsey, H Jiang, JH Kalin, Z Chen, PA Cole
Journal of the American Chemical Society 140 (30), 9374-9378, 2018
Regulation of S-adenosylhomocysteine hydrolase by lysine acetylation
Y Wang, JM Kavran, Z Chen, KR Karukurichi, DJ Leahy, PA Cole
Journal of Biological Chemistry 289 (45), 31361-31372, 2014
Inhibition of signal transducer and activator of transcription 3 and cyclooxygenase-2 is involved in radiosensitization of cepharanthine in HeLa cells
Z Fang, Y Li, Z Chen, J Wang, L Zhu
International Journal of Gynecologic Cancer 23 (4), 2013
Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases
H Jiang, SN Thomas, Z Chen, CY Chiang, PA Cole
Journal of Biological Chemistry 294 (46), 17421-17436, 2019
Formation, recognition and bioactivities of a novel G-quadruplex in the STAT3 gene
S Lin, S Li, Z Chen, X He, Y Zhang, X Xu, M Xu, G Yuan
Bioorganic & medicinal chemistry letters 21 (19), 5987-5991, 2011
Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs
MS Taylor, DR Dempsey, Y Hwang, Z Chen, N Chu, JD Boeke, PA Cole
Bioorganic chemistry 62, 64-73, 2015
The structural basis of PTEN regulation by multi-site phosphorylation
DR Dempsey, T Viennet, R Iwase, E Park, S Henriquez, Z Chen, ...
Nature Structural & Molecular Biology 28 (10), 858-868, 2021
What's new about the mechanism of methotrexate action in psoriasis?
Z Chen
British Journal of Dermatology 179 (4), 818-819, 2018
The biological functions of G-quadruplex
Z Chen, MH Xiu, SF Li, M Xu
Sheng li ke xue jin zhan [Progress in physiology] 41 (5), 329-334, 2010
Enzymatic analysis of WWP2 E3 ubiquitin ligase using protein microarrays identifies autophagy-related substrates
H Jiang, CY Chiang, Z Chen, S Nathan, G D’Agostino, JA Paulo, G Song, ...
Journal of Biological Chemistry 298 (5), 2022
Targeting E3 ubiquitin ligases to sensitize cancer radiation therapy
Z Chen, W Xu
Precision Radiation Oncology 3 (3), 105-110, 2019
EstG is a novel esterase required for cell envelope integrity in Caulobacter
AK Daitch, BC Orsburn, Z Chen, L Alvarez, CD Eberhard, K Sundararajan, ...
Current Biology, 2022
The system can't perform the operation now. Try again later.
Articles 1–20