An activity-guided map of electrophile-cysteine interactions in primary human T cells EV Vinogradova, X Zhang, D Remillard, DC Lazar, RM Suciu, Y Wang, ... Cell 182 (4), 1009-1026. e29, 2020 | 219 | 2020 |
Synthesis of redshifted azobenzene photoswitches by late‐stage functionalization DB Konrad, JA Frank, D Trauner Chemistry–A European Journal 22 (13), 4364-4368, 2016 | 140 | 2016 |
Computational design and synthesis of a deeply red-shifted and bistable azobenzene DB Konrad, G Savasci, L Allmendinger, D Trauner, C Ochsenfeld, AM Ali Journal of the American Chemical Society 142 (14), 6538-6547, 2020 | 123 | 2020 |
Orthogonal optical control of a G protein-coupled receptor with a SNAP-tethered photochromic ligand J Broichhagen, A Damijonaitis, J Levitz, KR Sokol, P Leippe, D Konrad, ... ACS central science 1 (7), 383-393, 2015 | 119 | 2015 |
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors J Levitz, J Broichhagen, P Leippe, D Konrad, D Trauner, EY Isacoff Proceedings of the National Academy of Sciences 114 (17), E3546-E3554, 2017 | 73 | 2017 |
PhoDAGs enable optical control of diacylglycerol-sensitive transient receptor potential channels T Leinders-Zufall, U Storch, K Bleymehl, MM y Schnitzler, JA Frank, ... Cell Chemical Biology 25 (2), 215-223. e3, 2018 | 60 | 2018 |
Light-controlled lipid interaction and membrane organization in photolipid bilayer vesicles P Urban, SD Pritzl, DB Konrad, JA Frank, C Pernpeintner, CR Roeske, ... Langmuir 34 (44), 13368-13374, 2018 | 59 | 2018 |
A lipid photoswitch controls fluidity in supported bilayer membranes P Urban, SD Pritzl, MF Ober, CF Dirscherl, C Pernpeintner, DB Konrad, ... Langmuir 36 (10), 2629-2634, 2020 | 46 | 2020 |
In situ ‘trans-metal trapping’: An efficient way to extend the scope of aromatic deprotometalation NM Brikci-Nigassa, G Bentabed-Ababsa, W Erb, F Mongin Synthesis 50 (18), 3615-3633, 2018 | 42 | 2018 |
Selective photoswitchable allosteric agonist of a G protein-coupled receptor P Donthamsetti, DB Konrad, B Hetzler, Z Fu, D Trauner, EY Isacoff Journal of the American Chemical Society 143 (24), 8951-8956, 2021 | 32 | 2021 |
In Vivo Photopharmacology Enabled by Multifunctional Fibers JA Frank, MJ Antonini, PH Chiang, A Canales, DB Konrad, IC Garwood, ... ACS chemical neuroscience 11 (22), 3802-3813, 2020 | 30 | 2020 |
Photolipid bilayer permeability is controlled by transient pore formation SD Pritzl, P Urban, A Prasselsperger, DB Konrad, JA Frank, D Trauner, ... Langmuir 36 (45), 13509-13515, 2020 | 28 | 2020 |
Optical membrane control with red light enabled by red-shifted photolipids SD Pritzl, DB Konrad, MF Ober, AF Richter, JA Frank, B Nickel, D Trauner, ... Langmuir 38 (1), 385-393, 2021 | 25 | 2021 |
Selective lithiation, magnesiation, and zincation of unsymmetrical azobenzenes using continuous flow M Ketels, DB Konrad, K Karaghiosoff, D Trauner, P Knochel Organic letters 19 (7), 1666-1669, 2017 | 25 | 2017 |
Optical control of GIRK channels using visible light JB Trads, J Burgstaller, L Laprell, DB Konrad, CD Weaver, H Baier, ... Organic & Biomolecular Chemistry 15 (1), 76-81, 2017 | 24 | 2017 |
A concise synthesis of tetrodotoxin DB Konrad, KP Rühmann, H Ando, BE Hetzler, N Strassner, KN Houk, ... Science 377 (6604), 411-415, 2022 | 20 | 2022 |
7-Dehydrocholesterol is an endogenous suppressor of ferroptosis FP Freitas, H Alborzinia, AF Dos Santos, P Nepachalovich, L Pedrera, ... Nature 626 (7998), 401-410, 2024 | 18 | 2024 |
Light-induced lipid mixing implies a causal role of lipid splay in membrane fusion HA Scheidt, K Kolocaj, DB Konrad, JA Frank, D Trauner, D Langosch, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (11), 183438, 2020 | 18 | 2020 |
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning DF Nippa, K Atz, R Hohler, AT Müller, A Marx, C Bartelmus, G Wuitschik, ... Nature Chemistry 16 (2), 239-248, 2024 | 17 | 2024 |
Selective Zincation of 1, 2-Dicyanobenzene and related Benzonitriles in continuous flow using in situ trapping metalations M Ketels, DS Ziegler, P Knochel Synlett 28 (20), 2817-2822, 2017 | 14 | 2017 |