Jan Stöhr
Jan Stöhr
Head of Parkinson's Disease Biology - AbbVie
Verified email at - Homepage
Cited by
Cited by
Short peptides self-assemble to produce catalytic amyloids
CM Rufo, YS Moroz, OV Moroz, J Stöhr, TA Smith, X Hu, WF DeGrado, ...
Nature chemistry 6 (4), 303-309, 2014
Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions
J Stöhr, JC Watts, ZL Mensinger, A Oehler, SK Grillo, SJ DeArmond, ...
Proceedings of the National Academy of Sciences 109 (27), 11025-11030, 2012
Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients
JC Watts, C Condello, J Stöhr, A Oehler, J Lee, SJ DeArmond, L Lannfelt, ...
Proceedings of the National Academy of Sciences 111 (28), 10323-10328, 2014
Propagation of prions causing synucleinopathies in cultured cells
AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, ...
Proceedings of the National Academy of Sciences 112 (35), E4949-E4958, 2015
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice
J Stöhr, C Condello, JC Watts, L Bloch, A Oehler, M Nick, SJ DeArmond, ...
Proceedings of the National Academy of Sciences 111 (28), 10329-10334, 2014
Mechanisms of prion protein assembly into amyloid
J Stöhr, N Weinmann, H Wille, T Kaimann, L Nagel-Steger, E Birkmann, ...
Proceedings of the National Academy of Sciences 105 (7), 2409-2414, 2008
Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer’s disease
C Condello, T Lemmin, J Stöhr, M Nick, Y Wu, AM Maxwell, JC Watts, ...
Proceedings of the National Academy of Sciences 115 (4), E782-E791, 2018
Aβ and tau prion-like activities decline with longevity in the Alzheimer’s disease human brain
A Aoyagi, C Condello, J Stöhr, W Yue, BM Rivera, JC Lee, AL Woerman, ...
Science translational medicine 11 (490), eaat8462, 2019
Zinc-binding structure of a catalytic amyloid from solid-state NMR
M Lee, T Wang, OV Makhlynets, Y Wu, NF Polizzi, H Wu, PM Gosavi, ...
Proceedings of the National Academy of Sciences 114 (24), 6191-6196, 2017
Inhibition of cytotoxicity and amyloid fibril formation by a d-amino acid peptide that specifically binds to Alzheimer’s disease amyloid peptide
K Wiesehan, J Stöhr, L Nagel-Steger, T Van Groen, D Riesner, D Willbold
Protein Engineering, Design & Selection 21 (4), 241-246, 2008
Structural changes of membrane-anchored native PrPC
K Elfrink, J Ollesch, J Stöhr, D Willbold, D Riesner, K Gerwert
Proceedings of the National Academy of Sciences 105 (31), 10815-10819, 2008
Structural polymorphism of Alzheimer’s β-amyloid fibrils as controlled by an E22 switch: A solid-state NMR study
MR Elkins, T Wang, M Nick, H Jo, T Lemmin, SB Prusiner, WF DeGrado, ...
Journal of the American Chemical Society 138 (31), 9840-9852, 2016
Assembly of natural and recombinant prion protein into fibrils
KW Leffers, H Wille, J Stöhr, E Junger, SB Prusiner, D Riesner
Walter de Gruyter 386 (6), 569-580, 2005
Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein
JC Watts, K Giles, J Stöhr, A Oehler, S Bhardwaj, SK Grillo, S Patel, ...
Proceedings of the National Academy of Sciences 109 (9), 3498-3503, 2012
Spontaneous generation of anchorless prions in transgenic mice
J Stöhr, JC Watts, G Legname, A Oehler, A Lemus, HOB Nguyen, ...
Proceedings of the National Academy of Sciences 108 (52), 21223-21228, 2011
Aβ propagation and strains: Implications for the phenotypic diversity in Alzheimer's disease
C Condello, J Stöehr
Neurobiology of disease 109, 191-200, 2018
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells
J Stöhr, H Wu, M Nick, Y Wu, M Bhate, C Condello, N Johnson, J Rodgers, ...
Nature chemistry 9 (9), 874-881, 2017
Protease-resistant prions selectively decrease Shadoo protein
JC Watts, J Stöhr, S Bhardwaj, H Wille, A Oehler, SJ DeArmond, K Giles, ...
PLoS Pathogens 7 (11), e1002382, 2011
Mechanism of scrapie prion precipitation with phosphotungstate anions
DJ Levine, J Stöhr, LE Falese, J Ollesch, H Wille, SB Prusiner, JR Long
ACS chemical biology 10 (5), 1269-1277, 2015
Prion protein—antibody complexes characterized by chromatography-coupled small-angle X-ray scattering
L Carter, SJ Kim, D Schneidman-Duhovny, J Stöhr, G Poncet-Montange, ...
Biophysical journal 109 (4), 793-805, 2015
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