| Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal model C Krul, C Humblot, C Philippe, M Vermeulen, M van Nuenen, R Havenaar, ... Carcinogenesis 23 (6), 1009-1016, 2002 | 220 | 2002 |
| Of the major phenolic acids formed during human microbial fermentation of tea, citrus, and soy flavonoid supplements, only 3, 4-dihydroxyphenylacetic acid has antiproliferative … K Gao, A Xu, C Krul, K Venema, Y Liu, Y Niu, J Lu, L Bensoussan, ... The Journal of nutrition 136 (1), 52-57, 2006 | 218 | 2006 |
| Human lung epithelial cell cultures for analysis of inhaled toxicants: Lessons learned and future directions PS Hiemstra, G Grootaers, AM van der Does, CAM Krul, IM Kooter Toxicology in vitro 47, 137-146, 2018 | 177 | 2018 |
| A practical guide for probiotics applied to the case of antibiotic-associated diarrhea in The Netherlands V Agamennone, CAM Krul, G Rijkers, R Kort BMC gastroenterology 18, 1-12, 2018 | 127 | 2018 |
| Development of a panel of high-throughput reporter-gene assays to detect genotoxicity and oxidative stress SC van der Linden, ARM von Bergh, BMA van Vught-Lussenburg, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 760, 23-32, 2014 | 124 | 2014 |
| Analysis of urinary caffeine metabolites to assess biotransformation enzyme activities by reversed-phase high-performance liquid chromatography C Krul, G Hageman Journal of Chromatography B: Biomedical Sciences and Applications 709 (1), 27-34, 1998 | 124 | 1998 |
| A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices J Westerhout, E van de Steeg, D Grossouw, EE Zeijdner, CAM Krul, ... European Journal of Pharmaceutical Sciences 63, 167-177, 2014 | 119 | 2014 |
| Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal model C Krul, A Luiten-Schuite, A Tenfelde, B van Ommen, H Verhagen, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 474 (1 …, 2001 | 105 | 2001 |
| Application of a dynamic in vitro gastrointestinal tract model to study the availability of food mutagens, using heterocyclic aromatic amines as model compounds C Krul, A Luiten-Schuite, R Baan, H Verhagen, G Mohn, V Feron, ... Food and Chemical Toxicology 38 (9), 783-792, 2000 | 104 | 2000 |
| Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling M Verwei, JA van Burgsteden, CAM Krul, JJM van de Sandt, AP Freidig Toxicology Letters 165 (1), 79-87, 2006 | 103 | 2006 |
| Reduction of use of animals in regulatory genotoxicity testing: identification and implementation opportunities—report from an ECVAM workshop S Pfuhler, D Kirkland, P Kasper, M Hayashi, P Vanparys, P Carmichael, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 680 (1-2 …, 2009 | 100 | 2009 |
| The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing–The report of an ECVAM–EFPIA workshop M Ceridono, P Tellner, D Bauer, J Barroso, N Alépée, R Corvi, ... Regulatory Toxicology and Pharmacology 63 (3), 480-488, 2012 | 99 | 2012 |
| Formation and removal of genotoxic activity during UV/H2O2–GAC treatment of drinking water MB Heringa, DJH Harmsen, EF Beerendonk, AA Reus, CAM Krul, ... Water Research 45 (1), 366-374, 2011 | 99 | 2011 |
| Regional expression levels of drug transporters and metabolizing enzymes along the pig and human intestinal tract and comparison with Caco-2 cells SFC Vaessen, MMH van Lipzig, RHH Pieters, CAM Krul, HM Wortelboer, ... Drug metabolism and disposition 45 (4), 353-360, 2017 | 90 | 2017 |
| Considering new methodologies in strategies for safety assessment of foods and food ingredients BJ Blaauboer, AR Boobis, B Bradford, A Cockburn, A Constable, ... Food and Chemical Toxicology 91, 19-35, 2016 | 80 | 2016 |
| Toxicological characterization of diesel engine emissions using biodiesel and a closed soot filter IM Kooter, MATM van Vugt, AD Jedynska, PC Tromp, MMG Houtzager, ... Atmospheric Environment 45 (8), 1574-1580, 2011 | 79 | 2011 |
| Comet assay in reconstructed 3D human epidermal skin models—investigation of intra-and inter-laboratory reproducibility with coded chemicals AA Reus, K Reisinger, TR Downs, GJ Carr, A Zeller, R Corvi, CAM Krul, ... Mutagenesis 28 (6), 709-720, 2013 | 72 | 2013 |
| Intragastric formation and modulation of N-nitrosodimethylamine in a dynamic in vitro gastrointestinal model under human physiological conditions CAM Krul, MJ Zeilmaker, RC Schothorst, R Havenaar Food and chemical toxicology 42 (1), 51-63, 2004 | 72 | 2004 |
| 3.7. Genotoxicity and mutagenicity D Maurici, M Aardema, R Corvi, M Kleber, C Krul, C Laurent, N Loprieno, ... Alternatives to laboratory animals 33 (1_suppl), 117-130, 2005 | 69 | 2005 |
| Toxicology in the 21st century–working our way towards a visionary reality N Berg, B De Wever, HW Fuchs, M Gaca, C Krul, EL Roggen Toxicology in Vitro 25 (4), 874-881, 2011 | 68 | 2011 |
