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Dr. Saurabh Gautam
Dr. Saurabh Gautam
Senior Manager at Novartis
Adresă de e-mail confirmată pe novartis.com
Titlu
Citat de
Citat de
Anul
Do macromolecular crowding agents exert only an excluded volume effect? A protein solvation study
SK Mukherjee, S Gautam, S Biswas, J Kundu, PK Chowdhury
The Journal of Physical Chemistry B 119 (44), 14145-14156, 2015
682015
A Novel α-L-Arabinofuranosidase of Family 43 Glycoside Hydrolase (Ct43Araf) from Clostridium thermocellum
S Ahmed, AS Luis, JLA Bras, A Ghosh, S Gautam, MN Gupta, ...
PloS one 8 (9), e73575, 2013
572013
Polyphenols in combination with β-cyclodextrin can inhibit and disaggregate α-synuclein amyloids under cell mimicking conditions: A promising therapeutic alternative
S Gautam, S Karmakar, R Batra, P Sharma, P Pradhan, J Singh, B Kundu, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1865 (5), 589-603, 2017
532017
β-cyclodextrin and curcumin, a potent cocktail for disaggregating and/or inhibiting amyloids: a case study with α-synuclein
S Gautam, S Karmakar, A Bose, PK Chowdhury
Biochemistry 53 (25), 4081-4083, 2014
492014
The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends
MM Schneider, S Gautam, TW Herling, E Andrzejewska, G Krainer, ...
Nature Communications 12 (1), 5999, 2021
472021
A facile and green ultrasonic-assisted synthesis of BSA conjugated silver nanoparticles
S Gautam, P Dubey, MN Gupta
Colloids and Surfaces B: Biointerfaces 102, 879-883, 2013
322013
Non-chromatographic strategies for protein refolding
S Gautam, P Dubey, G Mohmad Rather, M N Gupta
Recent Patents on Biotechnology 6 (1), 57-68, 2012
282012
Unusual effects of crowders on heme retention in myoglobin
J Kundu, U Kar, S Gautam, S Karmakar, PK Chowdhury
FEBS letters 589 (24), 3807-3815, 2015
242015
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
I Saha, P Yuste-Checa, M Da Silva Padilha, Q Guo, R Körner, ...
Nature communications 14 (1), 560, 2023
202023
Smart polymer mediated purification and recovery of active proteins from inclusion bodies
S Gautam, P Dubey, P Singh, S Kesavardhana, R Varadarajan, MN Gupta
Journal of Chromatography A 1235, 10-25, 2012
172012
Microwave assisted solubilization of inclusion bodies
I Datta, S Gautam, MN Gupta
Sustainable Chemical Processes 1, 1-7, 2013
142013
Simultaneous refolding and purification of recombinant proteins by macro-(affinity ligand) facilitated three-phase partitioning
S Gautam, P Dubey, P Singh, R Varadarajan, MN Gupta
Analytical biochemistry 430 (1), 56-64, 2012
132012
Dendrons and dendrimers as pseudochaperonins for refolding of proteins
P Dubey, S Gautam, PPP Kumar, S Sadanandan, V Haridas, MN Gupta
RSC advances 3 (21), 8016-8020, 2013
112013
Role of smart polymers in protein purification and refolding
S Gautam, P Dubey, R Varadarajan, MN Gupta
Bioengineered 3 (5), 286-288, 2012
102012
Structure and functional investigation of ligand binding by a family 35 carbohydrate binding module (Ct CBM35) of β-mannanase of family 26 glycoside hydrolase from Clostridium …
A Ghosh, AK Verma, S Gautam, MN Gupta, A Goyal
Biochemistry (Moscow) 79, 672-686, 2014
92014
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
I Saha, P Yuste-Checa, MD Silva Padilha, Q Guo, R Körner, H Holthusen, ...
BioRxiv, 2022.02. 18.481043, 2022
72022
Green synthesis of nanocomposites consisting of silver and protease alpha chymotrypsin
J Mukherjee, D Malhotra, S Gautam, MN Gupta
Ultrasonics sonochemistry 20 (4), 1054-1061, 2013
72013
Emerging trends in designing short and efficient protein purification protocols
S Gautam, J Mukherjee, I Roy, MN Gupta
Am J Biochem Biotechnol 8 (4), 230-254, 2012
72012
Exploring the potency of the naturally occurring polyphenol curcumin as a probe for protein aggregation in crowded environments
S Karmakar, S Chakraborty, S Gautam, PK Chowdhury
International journal of biological macromolecules 141, 1088-1101, 2019
52019
Structural characterization of a novel KH-domain containing plant chloroplast endonuclease
AK Rout, H Singh, S Patel, V Raghvan, S Gautam, R Minda, BJ Rao, ...
Scientific reports 8 (1), 13750, 2018
52018
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