Patrik Johansson
Patrik Johansson
Discovery Sciences Lead, AstraZeneca R&D
Verified email at
Cited by
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X-ray structure of Candida antarctica lipase A shows a novel lid structure and a likely mode of interfacial activation
DJ Ericsson, A Kasrayan, P Johansson, T Bergfors, AG Sandström, ...
Journal of molecular biology 376 (1), 109-119, 2008
Structural insight into allosteric modulation of protease-activated receptor 2
RKY Cheng, C Fiez-Vandal, O Schlenker, K Edman, B Aggeler, DG Brown, ...
Nature 545 (7652), 112-115, 2017
Crystal structures of a poplar xyloglucan endotransglycosylase reveal details of transglycosylation acceptor binding
P Johansson, H Brumer III, MJ Baumann, AM Kallas, H Henriksson, ...
The Plant Cell 16 (4), 874-886, 2004
Crystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamily
T Sjögren, J Nord, M Ek, P Johansson, G Liu, S Geschwindner
Proceedings of the National Academy of Sciences 110 (10), 3806-3811, 2013
Inhibition of the fungal fatty acid synthase type I multienzyme complex
P Johansson, B Wiltschi, P Kumari, B Kessler, C Vonrhein, J Vonck, ...
Proceedings of the National Academy of Sciences 105 (35), 12803-12808, 2008
Ligand binding thermodynamics in drug discovery: still a hot tip?
S Geschwindner, J Ulander, P Johansson
Journal of Medicinal Chemistry 58 (16), 6321-6335, 2015
Enzymatic properties of native and deglycosylated hybrid aspen (Populus tremula×tremuloides) xyloglucan endotransglycosylase 16A expressed in Pichia pastoris
ÅM Kallas, K Piens, SE Denman, H Henriksson, J Fäldt, P Johansson, ...
Biochemical Journal 390 (1), 105-113, 2005
MraY–antibiotic complex reveals details of tunicamycin mode of action
JK Hakulinen, J Hering, G Brändén, H Chen, A Snijder, M Ek, ...
Nature chemical biology 13 (3), 265-267, 2017
New aminoimidazoles as β-secretase (BACE-1) inhibitors showing amyloid-β (Aβ) lowering in brain
Y Gravenfors, J Viklund, J Blid, T Ginman, S Karlström, J Kihlström, ...
Journal of medicinal chemistry 55 (21), 9297-9311, 2012
Core refinement toward permeable β-secretase (BACE-1) inhibitors with low hERG activity
T Ginman, J Viklund, J Malmstrom, J Blid, R Emond, R Forsblom, ...
Journal of Medicinal Chemistry 56 (11), 4181-4205, 2013
Dodecin is the key player in flavin homeostasis of archaea
M Grininger, H Staudt, P Johansson, J Wachtveitl, D Oesterhelt
Journal of Biological Chemistry 284 (19), 13068-13076, 2009
Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function
P Johansson, T Unge, A Cronin, M Arand, T Bergfors, TA Jones, ...
Journal of molecular biology 351 (5), 1048-1056, 2005
Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase
P Johansson, B Mulinacci, C Koestler, R Vollrath, D Oesterhelt, ...
Structure 17 (8), 1063-1074, 2009
Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
L Odqvist, Z Jevnikar, R Riise, L Öberg, M Rhedin, D Leonard, L Yrlid, ...
Annals of the Rheumatic Diseases 78 (10), 1363-1370, 2019
Structural and biochemical characterization of a halophilic archaeal alkaline phosphatase
A Wende, P Johansson, R Vollrath, M Dyall-Smith, D Oesterhelt, ...
Journal of molecular biology 400 (1), 52-62, 2010
Rv0216, a conserved hypothetical protein from Mycobacterium tuberculosis that is essential for bacterial survival during infection, has a double hotdog fold
A Castell, P Johansson, T Unge, TA Jones, K Bäckbro
Protein science 14 (7), 1850-1862, 2005
Duration and mechanisms of the increased natural cytotoxicity seen after chronic voluntary exercise in rats
IH Jonsdottir, C Johansson, A Asea, P Johansson, K Hellstrand, P Thoren, ...
Acta physiologica scandinavica 160 (4), 333-339, 1997
FAM3B PANDER and FAM3C ILEI represent a distinct class of signaling molecules with a non-cytokine-like fold
P Johansson, J Bernström, T Gorman, L Öster, S Bäckström, F Schweikart, ...
Structure 21 (2), 306-313, 2013
Development of a plate-based optical biosensor fragment screening methodology to identify phosphodiesterase 10A inhibitors
S Geschwindner, N Dekker, R Horsefield, A Tigerström, P Johansson, ...
Journal of Medicinal Chemistry 56 (8), 3228-3234, 2013
X‐ray structure of peptidyl‐prolyl cistrans isomerase A from Mycobacterium tuberculosis
LM Henriksson, P Johansson, T Unge, SL Mowbray
European journal of biochemistry 271 (20), 4107-4113, 2004
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