Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ... Cancer discovery 4 (3), 362-375, 2014 | 719 | 2014 |
Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers CR Pickering, J Zhang, SY Yoo, L Bengtsson, S Moorthy, DM Neskey, ... Cancer discovery 3 (7), 770-781, 2013 | 582 | 2013 |
Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1 J Lu, X Ye, F Fan, L Xia, R Bhattacharya, S Bellister, F Tozzi, E Sceusi, ... Cancer cell 23 (2), 171-185, 2013 | 486 | 2013 |
PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia Z Gu, ML Churchman, KG Roberts, I Moore, X Zhou, J Nakitandwe, ... Nature genetics 51 (2), 296-307, 2019 | 460 | 2019 |
Gfi-1 Encodes a Nuclear Zinc Finger Protein That Binds DNA and Functions as a Transcriptional Repressor PA Zweidler-Mckay, HL Grimes, MM Flubacher, PN Tsichlis Molecular and cellular biology 16 (8), 4024-4034, 1996 | 381 | 1996 |
Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults N Jain, KG Roberts, E Jabbour, K Patel, AK Eterovic, K Chen, ... Blood, The Journal of the American Society of Hematology 129 (5), 572-581, 2017 | 370 | 2017 |
The Gfi-1 Proto-Oncoprotein Contains a Novel Transcriptional Repressor Domain, SNAG, and Inhibits G1 Arrest Induced by Interleukin-2 Withdrawal HL Grimes, TO Chan, PA Zweidler-McKay, B Tong, PN Tsichlis Molecular and cellular biology 16 (11), 6263-6272, 1996 | 355 | 1996 |
Targetable kinase gene fusions in high-risk B-ALL: a study from the Children’s Oncology Group SC Reshmi, RC Harvey, KG Roberts, E Stonerock, A Smith, H Jenkins, ... Blood, The Journal of the American Society of Hematology 129 (25), 3352-3361, 2017 | 299 | 2017 |
Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies PA Zweidler-McKay, Y He, L Xu, CG Rodriguez, FG Karnell, AC Carpenter, ... Blood 106 (12), 3898-3906, 2005 | 278 | 2005 |
Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells MI Almeida, MS Nicoloso, L Zeng, C Ivan, R Spizzo, R Gafà, L Xiao, ... Gastroenterology 142 (4), 886-896. e9, 2012 | 233 | 2012 |
Targeted therapy in cancer AM Tsimberidou Cancer chemotherapy and pharmacology 76, 1113-1132, 2015 | 224 | 2015 |
Improved survival for children and young adults with T-lineage acute lymphoblastic leukemia: results from the Children’s Oncology Group AALL0434 methotrexate randomization SS Winter, KP Dunsmore, M Devidas, BL Wood, N Esiashvili, Z Chen, ... Journal of Clinical Oncology 36 (29), 2926, 2018 | 215 | 2018 |
Activating NOTCH1 mutations define a distinct subgroup of patients with adenoid cystic carcinoma who have poor prognosis, propensity to bone and liver metastasis, and potential … R Ferrarotto, Y Mitani, L Diao, I Guijarro, J Wang, P Zweidler-McKay, ... Journal of clinical oncology 35 (3), 352, 2017 | 198 | 2017 |
Critical role of notch signaling in osteosarcoma invasion and metastasis P Zhang, Y Yang, PA Zweidler-McKay, DPM Hughes Clinical Cancer Research 14 (10), 2962-2969, 2008 | 184 | 2008 |
Notch activation inhibits AML growth and survival: a potential therapeutic approach S Kannan, RM Sutphin, MG Hall, LS Golfman, W Fang, RM Nolo, LJ Akers, ... Journal of Experimental Medicine 210 (2), 321-337, 2013 | 179 | 2013 |
Absolute lymphocyte count is a novel prognostic indicator in ALL and AML: implications for risk stratification and future studies G De Angulo, C Yuen, SL Palla, PM Anderson, PA Zweidler‐McKay Cancer: Interdisciplinary International Journal of the American Cancer …, 2008 | 161 | 2008 |
Children’s Oncology Group AALL0434: a phase III randomized clinical trial testing nelarabine in newly diagnosed T-cell acute lymphoblastic leukemia KP Dunsmore, SS Winter, M Devidas, BL Wood, N Esiashvili, Z Chen, ... Journal of Clinical Oncology 38 (28), 3282, 2020 | 155 | 2020 |
The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis H Ling, K Pickard, C Ivan, C Isella, M Ikuo, R Mitter, R Spizzo, MD Bullock, ... Gut 65 (6), 977-989, 2016 | 151 | 2016 |
The genomic landscape of pediatric acute lymphoblastic leukemia SW Brady, KG Roberts, Z Gu, L Shi, S Pounds, D Pei, C Cheng, Y Dai, ... Nature genetics 54 (9), 1376-1389, 2022 | 148 | 2022 |
Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation U Popat, RS Mehta, K Rezvani, P Fox, K Kondo, D Marin, I McNiece, ... Blood, The Journal of the American Society of Hematology 125 (19), 2885-2892, 2015 | 148 | 2015 |