| How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers SD Taverna, H Li, AJ Ruthenburg, CD Allis, DJ Patel Nature structural & molecular biology 14 (11), 1025-1040, 2007 | 1676 | 2007 |
| Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark AJ Ruthenburg, CD Allis, J Wysocka Molecular cell 25 (1), 15-30, 2007 | 1298 | 2007 |
| Multivalent engagement of chromatin modifications by linked binding modules AJ Ruthenburg, H Li, DJ Patel, C David Allis Nature reviews Molecular cell biology 8 (12), 983-994, 2007 | 1145 | 2007 |
| Regulation of MLL1 H3K4 methyltransferase activity by its core components Y Dou, TA Milne, AJ Ruthenburg, S Lee, JW Lee, GL Verdine, CD Allis, ... Nature structural & molecular biology 13 (8), 713-719, 2006 | 834 | 2006 |
| Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions AJ Ruthenburg, H Li, TA Milne, S Dewell, RK McGinty, M Yuen, ... Cell 145 (5), 692-706, 2011 | 378 | 2011 |
| Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex AJ Ruthenburg, W Wang, DM Graybosch, H Li, CD Allis, DJ Patel, ... Nature structural & molecular biology 13 (8), 704-712, 2006 | 277 | 2006 |
| Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase H Wei, AJ Ruthenburg, SK Bechis, GL Verdine Journal of Biological Chemistry 280 (44), 37041-37047, 2005 | 262 | 2005 |
| Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis TA Milne, J Kim, GG Wang, SC Stadler, V Basrur, SJ Whitcomb, Z Wang, ... Molecular cell 38 (6), 853-863, 2010 | 234 | 2010 |
| Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA HC Losey, AJ Ruthenburg, GL Verdine Nature structural & molecular biology 13 (2), 153-159, 2006 | 196 | 2006 |
| Nuclear fractionation reveals thousands of chromatin-tethered noncoding RNAs adjacent to active genes MS Werner, AJ Ruthenburg Cell reports 12 (7), 1089-1098, 2015 | 174 | 2015 |
| An interactive database for the assessment of histone antibody specificity SB Rothbart, BM Dickson, JR Raab, AT Grzybowski, K Krajewski, AH Guo, ... Molecular cell 59 (3), 502-511, 2015 | 161 | 2015 |
| A superhelical spiral in the Escherichia coli DNA gyrase A C-terminal domain imparts unidirectional supercoiling bias AJ Ruthenburg, DM Graybosch, JC Huetsch, GL Verdine Journal of Biological Chemistry 280 (28), 26177-26184, 2005 | 102 | 2005 |
| Examining the roles of H3K4 methylation states with systematically characterized antibodies RN Shah, AT Grzybowski, EM Cornett, AL Johnstone, BM Dickson, ... Molecular cell 72 (1), 162-177. e7, 2018 | 99 | 2018 |
| Calibrating ChIP-Seq with nucleosomal internal standards to measure histone modification density genome wide AT Grzybowski, Z Chen, AJ Ruthenburg Molecular cell 58 (5), 886-899, 2015 | 85 | 2015 |
| Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription MS Werner, MA Sullivan, RN Shah, RD Nadadur, AT Grzybowski, V Galat, ... Nature structural & molecular biology 24 (7), 596-603, 2017 | 84 | 2017 |
| Recombinant antibodies to histone post-translational modifications T Hattori, JM Taft, KM Swist, H Luo, H Witt, M Slattery, A Koide, ... Nature methods 10 (10), 992-995, 2013 | 71 | 2013 |
| A mutation in histone H2B represents a new class of oncogenic driver RL Bennett, A Bele, EC Small, CM Will, B Nabet, JA Oyer, X Huang, ... Cancer discovery 9 (10), 1438-1451, 2019 | 61 | 2019 |
| Targeting the MTF2–MDM2 axis sensitizes refractory acute myeloid leukemia to chemotherapy HB Maganti, H Jrade, C Cafariello, JL Manias Rothberg, CJ Porter, ... Cancer discovery 8 (11), 1376-1389, 2018 | 43 | 2018 |
| Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation T Hattori, D Lai, IS Dementieva, SP Montaño, K Kurosawa, Y Zheng, ... Proceedings of the National Academy of Sciences 113 (8), 2092-2097, 2016 | 42 | 2016 |
| Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm XH Yang, RD Nadadur, CRE Hilvering, V Bianchi, M Werner, SR Mazurek, ... Elife 6, e31683, 2017 | 39 | 2017 |
