| Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury RC Lai, F Arslan, MM Lee, NSK Sze, A Choo, TS Chen, M Salto-Tellez, ... Stem cell research 4 (3), 214-222, 2010 | 2367 | 2010 |
| Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse … F Arslan, RC Lai, MB Smeets, L Akeroyd, A Choo, ENE Aguor, L Timmers, ... Stem cell research 10 (3), 301-312, 2013 | 1177 | 2013 |
| Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery RWY Yeo, RC Lai, B Zhang, SS Tan, Y Yin, BJ Teh, SK Lim Advanced drug delivery reviews 65 (3), 336-341, 2013 | 798 | 2013 |
| Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs TS Chen, RC Lai, MM Lee, ABH Choo, CN Lee, SK Lim Nucleic acids research 38 (1), 215-224, 2010 | 738 | 2010 |
| MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity S Zhang, SJ Chuah, RC Lai, JHP Hui, SK Lim, WS Toh Biomaterials 156, 16-27, 2018 | 736 | 2018 |
| Mesenchymal stem cells secrete immunologically active exosomes B Zhang, Y Yin, RC Lai, SS Tan, ABH Choo, SK Lim Stem cells and development 23 (11), 1233-1244, 2014 | 681 | 2014 |
| Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease RC Lai, TS Chen, SK Lim Regenerative medicine 6 (4), 481-492, 2011 | 631 | 2011 |
| Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes JE Park, HS Tan, A Datta, RC Lai, H Zhang, W Meng, SK Lim, SK Sze Molecular & cellular proteomics 9 (6), 1085-1099, 2010 | 625 | 2010 |
| Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration S Zhang, WC Chu, RC Lai, SK Lim, JHP Hui, WS Toh Osteoarthritis and cartilage 24 (12), 2135-2140, 2016 | 624 | 2016 |
| Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models CY Tan, RC Lai, W Wong, YY Dan, SK Lim, HK Ho Stem cell research & therapy 5, 1-14, 2014 | 579 | 2014 |
| Mesenchymal stem cell exosomes RC Lai, RWY Yeo, SK Lim Seminars in cell & developmental biology 40, 82-88, 2015 | 567 | 2015 |
| Exosomes for drug delivery—a novel application for the mesenchymal stem cell RC Lai, RWY Yeo, KH Tan, SK Lim Biotechnology advances 31 (5), 543-551, 2013 | 559 | 2013 |
| Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction L Timmers, SK Lim, IE Hoefer, F Arslan, RC Lai, AAM van Oorschot, ... Stem cell research 6 (3), 206-214, 2011 | 503 | 2011 |
| Proteolytic potential of the MSC exosome proteome: implications for an exosome-mediated delivery of therapeutic proteasome RC Lai, SS Tan, BJ Teh, SK Sze, F Arslan, DP De Kleijn, A Choo, SK Lim International journal of proteomics 2012, 2012 | 499 | 2012 |
| Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications KW Witwer, BWM Van Balkom, S Bruno, A Choo, M Dominici, M Gimona, ... Journal of extracellular vesicles 8 (1), 1609206, 2019 | 454 | 2019 |
| MSC exosome as a cell-free MSC therapy for cartilage regeneration: implications for osteoarthritis treatment WS Toh, RC Lai, JHP Hui, SK Lim Seminars in cell & developmental biology 67, 56-64, 2017 | 439 | 2017 |
| Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs TS Chen, F Arslan, Y Yin, SS Tan, RC Lai, ABH Choo, J Padmanabhan, ... Journal of translational medicine 9, 1-10, 2011 | 393 | 2011 |
| MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis S Zhang, KYW Teo, SJ Chuah, RC Lai, SK Lim, WS Toh Biomaterials 200, 35-47, 2019 | 383 | 2019 |
| Elucidating the secretion proteome of human embryonic stem cell-derived mesenchymal stem cells SK Sze, DPV de Kleijn, RC Lai, EKW Tan, H Zhao, KS Yeo, TY Low, ... Molecular & Cellular Proteomics 6 (10), 1680-1689, 2007 | 304 | 2007 |
| MSC exosome works through a protein-based mechanism of action WS Toh, RC Lai, B Zhang, SK Lim Biochemical Society Transactions 46 (4), 843-853, 2018 | 300 | 2018 |
