| Core signaling pathways in human pancreatic cancers revealed by global genomic analyses S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ... science 321 (5897), 1801-1806, 2008 | 4443 | 2008 |
| Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ... Science 324 (5933), 1457-1461, 2009 | 3386 | 2009 |
| Genomic analyses identify molecular subtypes of pancreatic cancer P Bailey, DK Chang, K Nones, AL Johns, AM Patch, MC Gingras, ... Nature 531 (7592), 47-52, 2016 | 2871 | 2016 |
| Distant metastasis occurs late during the genetic evolution of pancreatic cancer S Yachida, S Jones, I Bozic, T Antal, R Leary, B Fu, M Kamiyama, ... Nature 467 (7319), 1114-1117, 2010 | 2785 | 2010 |
| Whole genomes redefine the mutational landscape of pancreatic cancer N Waddell, M Pajic, AM Patch, DK Chang, KS Kassahn, P Bailey, ... Nature 518 (7540), 495-501, 2015 | 2431 | 2015 |
| Massive genomic rearrangement acquired in a single catastrophic event during cancer development PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ... cell 144 (1), 27-40, 2011 | 2423 | 2011 |
| A draft map of the human proteome MS Kim, SM Pinto, D Getnet, RS Nirujogi, SS Manda, R Chaerkady, ... Nature 509 (7502), 575-581, 2014 | 2325 | 2014 |
| Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ... Nature 475 (7354), 106-109, 2011 | 2146 | 2011 |
| Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ... Nature 491 (7424), 399-405, 2012 | 2081 | 2012 |
| Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma AD Rhim, PE Oberstein, DH Thomas, ET Mirek, CF Palermo, SA Sastra, ... Cancer cell 25 (6), 735-747, 2014 | 1880 | 2014 |
| Organoid models of human and mouse ductal pancreatic cancer SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ... Cell 160 (1), 324-338, 2015 | 1716 | 2015 |
| Virtual microdissection identifies distinct tumor-and stroma-specific subtypes of pancreatic ductal adenocarcinoma RA Moffitt, R Marayati, EL Flate, KE Volmar, SGH Loeza, KA Hoadley, ... Nature genetics 47 (10), 1168-1178, 2015 | 1575 | 2015 |
| The patterns and dynamics of genomic instability in metastatic pancreatic cancer PJ Campbell, S Yachida, LJ Mudie, PJ Stephens, ED Pleasance, ... Nature 467 (7319), 1109-1113, 2010 | 1503 | 2010 |
| DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer CA Iacobuzio-Donahue, B Fu, S Yachida, M Luo, H Abe, CM Henderson, ... Journal of clinical oncology 27 (11), 1806, 2009 | 1116 | 2009 |
| Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ... Science 324 (5924), 217-217, 2009 | 923 | 2009 |
| Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer VP Balachandran, M Łuksza, JN Zhao, V Makarov, JA Moral, R Remark, ... Nature 551 (7681), 512-516, 2017 | 892 | 2017 |
| Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers G Feldmann, S Dhara, V Fendrich, D Bedja, R Beaty, M Mullendore, ... Cancer research 67 (5), 2187-2196, 2007 | 831 | 2007 |
| Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis Y Miyamoto, A Maitra, B Ghosh, U Zechner, P Argani, ... Cancer cell 3 (6), 565-576, 2003 | 816 | 2003 |
| Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression RE Wilentz, CA Iacobuzio-Donahue, P Argani, DM McCarthy, JL Parsons, ... Cancer research 60 (7), 2002-2006, 2000 | 787 | 2000 |
| Organoid profiling identifies common responders to chemotherapy in pancreatic cancer H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 697 | 2018 |
Eileen M. O'ReillyMemorial Sloan Kettering Cancer CenterAdresă de e-mail confirmată pe mskcc.org
