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Consuelo Torrini
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Year
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models.
SMD Nguyen T, Zhang Y, Shang E, Shu C, Torrini C, Zhao J, Bianchetti E, Mela ...
J Clin Invest, 2020
1242020
Common regulatory pathways mediate activity of microRNAs inducing cardiomyocyte proliferation
C Torrini, RJ Cubero, E Dirkx, L Braga, H Ali, G Prosdocimo, MI Gutierrez, ...
Cell reports 27 (9), 2759-2771. e5, 2019
902019
MET inhibition elicits PGC1α-dependent metabolic reprogramming in glioblastoma
Y Zhang, TTT Nguyen, E Shang, A Mela, N Humala, A Mahajan, J Zhao, ...
Cancer research 80 (1), 30-43, 2020
402020
Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl-xL inhibition.
SMD Nguyen TTT, Ishida CT, Shang E, Shu C, Torrini C, Zhang Y, Bianchetti E ...
EMBO Mol Med, 2019
392019
Lactate is an epigenetic metabolite that drives survival in model systems of glioblastoma
C Torrini, TTT Nguyen, C Shu, A Mela, N Humala, A Mahajan, EH Seeley, ...
Molecular cell 82 (16), 3061-3076. e6, 2022
352022
Induction of synthetic lethality by activation of mitochondrial ClpP and inhibition of HDAC1/2 in glioblastoma
TTT Nguyen, E Shang, S Schiffgens, C Torrini, C Shu, HO Akman, ...
Clinical Cancer Research 28 (9), 1881-1895, 2022
222022
A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration
A Raso, E Dirkx, V Sampaio-Pinto, H El Azzouzi, RJ Cubero, ...
Nature communications 12 (1), 4808, 2021
172021
Notch pathway activation enhances cardiosphere in vitro expansion
I Secco, L Barile, C Torrini, L Zentilin, G Vassalli, M Giacca, C Collesi
Journal of cellular and molecular medicine 22 (11), 5583-5595, 2018
72018
Common regulatory pathways mediate activity of microRNAs inducing cardiomyocyte proliferation. Cell Rep 27: 2759–2771. e5
C Torrini, RJ Cubero, E Dirkx, L Braga, H Ali, G Prosdocimo, MI Gutierrez, ...
52019
CDK4/6 inhibition sensitizes intracranial tumors to PD-1 blockade in preclinical models of brain metastasis
N Nayyar, MA de Sauvage, J Chuprin, EM Sullivan, M Singh, C Torrini, ...
Clinical Cancer Research 30 (2), 420-435, 2024
32024
The ERK inhibitor LY3214996 augments anti-PD-1 immunotherapy in preclinical mouse models of BRAFV600E melanoma brain metastasis
MA de Sauvage, C Torrini, E Nieblas-Bedolla, EJ Summers, E Sullivan, ...
Neuro-oncology 26 (5), 889-901, 2024
12024
DDDR-05. ERK INHIBITION INCREASES SENSITIVITY TO ANTI-PD-1 THERAPY IN A MOUSE MODEL OF BRAF MUTANT MELANOMA BRAIN METASTASIS
PB Magali de Sauvage, Naema Nayyar, Consuelo Torrini, Edwin Nieblas-Bedolla
Neuro-Oncology 24 (Issue Supplement_7), Page vii99, 2022
12022
A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration (vol 12, 4808, 2021)
A Raso, E Dirkx, V Sampaio-Pinto, H el Azzouzi, RJ Cubero, ...
NATURE COMMUNICATIONS 13 (1), 2022
12022
Author Correction: A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration
A Raso, E Dirkx, V Sampaio-Pinto, H El Azzouzi, RJ Cubero, ...
nature communications 13, 2022
12022
OGDH and Bcl-xL loss causes synthetic lethality in glioblastoma
TTT Nguyen, C Torrini, E Shang, C Shu, JY Mun, Q Gao, N Humala, ...
JCI insight 9 (8), 2024
2024
EXTH-42. PRECLINICAL INVESTIGATION OF A NOVEL BRAIN PENETRANT MEK INHIBITOR TO TARGET BRAIN METASTASIS
E Yamazawa, N Nayyar, N Ijad, C Torrini, M De Sauvage, C Migliarese, ...
Neuro-Oncology 25 (Supplement_5), v233-v234, 2023
2023
EXTH-45. DEVELOPMENT OF COMBINATION THERAPIES OF KRASG12C INHIBITOR ADAGRASIB IN PRECLINICAL MODELS OF BRAIN METASTASIS
C Torrini, C Migliarese, E Summers, FT Demir, N Ijad, N Nayyar, ...
Neuro-Oncology 25 (Supplement_5), v234-v234, 2023
2023
Dyrk1a kinase controls cardiomyocyte proliferation
G Rizzari, E Dirkx, C Torrini, M Tomczyk, M Mano, M Giacca
Journal of Molecular and Cellular Cardiology 173, S109, 2022
2022
TMET-39. INHIBITION OF THE TCA-CYCLE IS SYNTHETICALLY LETHAL WITH LOSS OF FUNCTION OF BCL-XL IN GLIOBLASTOMA
MS Trang Nguyen, Enyuan Shang, Consuelo Torrini, Chang Shu, Mike-Andrew ...
Neuro-Oncology 24 (Issue Supplement_7), vii270, 2022
2022
Abstract P1002: Elucidating The Role Of Dyrk1a Kinase In Controlling Cardiomyocyte Proliferation
G Rizzari, E Dirkx, C Torrini, M Tomczyk, M Mano, M Giacca
Circulation Research 131 (Suppl_1), AP1002-AP1002, 2022
2022
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Articles 1–20