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Eric Raabe
Eric Raabe
Associate professor of pediatric oncology, Johns Hopkins University
Adresă de e-mail confirmată pe jhmi.edu
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Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
CS Grasso, Y Tang, N Truffaux, NE Berlow, L Liu, MA Debily, MJ Quist, ...
Nature medicine 21 (6), 555-559, 2015
6122015
Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors
S Gholamin, SS Mitra, AH Feroze, J Liu, SA Kahn, M Zhang, R Esparza, ...
Science translational medicine 9 (381), eaaf2968, 2017
3502017
Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG
LQ Sun, DW Lee, Q Zhang, W Xiao, EH Raabe, A Meeker, D Miao, ...
Genes & development 18 (9), 1035-1046, 2004
2232004
BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model
EH Raabe, KS Lim, JM Kim, A Meeker, X Mao, G Nikkhah, J Maciaczyk, ...
Clinical Cancer Research 17 (11), 3590-3599, 2011
1972011
Integrated proteogenomic characterization across major histological types of pediatric brain cancer
F Petralia, N Tignor, B Reva, M Koptyra, S Chowdhury, D Rykunov, A Krek, ...
Cell 183 (7), 1962-1985. e31, 2020
1962020
Prevalence and functional consequence of PHOX2B mutations in neuroblastoma
EH Raabe, M Laudenslager, C Winter, N Wasserman, K Cole, ...
Oncogene 27 (4), 469-476, 2008
1782008
Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening
GL Lin, KM Wilson, M Ceribelli, BZ Stanton, PJ Woo, S Kreimer, EY Qin, ...
Science translational medicine 11 (519), eaaw0064, 2019
1502019
The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models
N Martínez-Vélez, M Garcia-Moure, M Marigil, M González-Huarriz, ...
Nature communications 10 (1), 2235, 2019
1202019
Management of pediatric and adult patients with medulloblastoma
AM Martin, E Raabe, C Eberhart, KJ Cohen
Current treatment options in oncology 15, 581-594, 2014
1112014
Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes
AM Saratsis, M Kambhampati, K Snyder, S Yadavilli, JM Devaney, ...
Acta neuropathologica 127, 881-895, 2014
1092014
Proliferation-associated SNF2-like gene (PASG): a SNF2 family member altered in leukemia1
DW Lee, K Zhang, ZQ Ning, EH Raabe, S Tintner, R Wieland, BJ Wilkins, ...
Cancer research 60 (13), 3612-3622, 2000
1072000
Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target
M Hütt-Cabezas, MA Karajannis, D Zagzag, S Shah, I Horkayne-Szakaly, ...
Neuro-oncology 15 (12), 1604-1614, 2013
872013
Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target
MF Weingart, JJ Roth, M Hutt-Cabezas, TM Busse, H Kaur, A Price, ...
Oncotarget 6 (5), 3165, 2015
852015
ZEB1 promotes invasion in human fetal neural stem cells and hypoxic glioma neurospheres
UD Kahlert, AK Suwala, EH Raabe, FA Siebzehnrubl, MJ Suarez, BA Orr, ...
Brain pathology 25 (6), 724-732, 2015
752015
Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas
LY Ballester, Z Wang, S Shandilya, M Miettinen, PC Burger, CG Eberhart, ...
The American journal of surgical pathology 37 (9), 1357-1364, 2013
742013
LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program
X Mao, M Hütt-Cabezas, BA Orr, M Weingart, I Taylor, AKD Rajan, Y Odia, ...
Oncotarget 4 (7), 1050, 2013
742013
Disrupting NOTCH slows diffuse intrinsic pontine glioma growth, enhances radiation sensitivity, and shows combinatorial efficacy with bromodomain inhibition
IC Taylor, M Hütt-Cabezas, WD Brandt, M Kambhampati, J Nazarian, ...
Journal of Neuropathology & Experimental Neurology 74 (8), 778-790, 2015
722015
ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner
JA Brosnan-Cashman, M Yuan, MK Graham, AJ Rizzo, KM Myers, ...
PloS one 13 (9), e0204159, 2018
692018
Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma
S Ahsan, EH Raabe, MC Haffner, A Vaghasia, KE Warren, M Quezado, ...
Acta neuropathologica communications 2, 1-9, 2014
672014
DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets
AR Hanaford, TC Archer, A Price, UD Kahlert, J Maciaczyk, G Nikkhah, ...
Clinical Cancer Research 22 (15), 3903-3914, 2016
622016
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