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Viruses as quasispecies: biological implications
E Domingo, V Martin, C Perales, A Grande-Perez, J Garcia-Arriaza, ...
Quasispecies: concept and implications for virology, 51-82, 2006
The evolution of poxvirus vaccines
L Sánchez-Sampedro, B Perdiguero, E Mejías-Pérez, J García-Arriaza, ...
Viruses 7 (4), 1726-1803, 2015
Evolutionary transition toward defective RNAs that are infectious by complementation
J García-Arriaza, SC Manrubia, M Toja, E Domingo, C Escarmís
Journal of virology 78 (21), 11678-11685, 2004
A novel poxvirus-based vaccine, MVA-CHIKV, is highly immunogenic and protects mice against chikungunya infection
J García-Arriaza, V Cepeda, D Hallengärd, CÓS Sorzano, BM Kümmerer, ...
Journal of Virology 88 (6), 3527-3547, 2014
Viral genome segmentation can result from a trade-off between genetic content and particle stability
S Ojosnegros, J Garcia-Arriaza, C Escarmis, SC Manrubia, C Perales, ...
PLoS genetics 7 (3), e1001344, 2011
The HIV/AIDS vaccine candidate MVA-B administered as a single immunogen in humans triggers robust, polyfunctional, and selective effector memory T cell responses to HIV-1 antigens
CE Gómez, JL Nájera, B Perdiguero, J García-Arriaza, COS Sorzano, ...
Journal of virology 85 (21), 11468-11478, 2011
Enhancing poxvirus vectors vaccine immunogenicity
J García-Arriaza, M Esteban
Human vaccines & immunotherapeutics 10 (8), 2235-2244, 2014
COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike protein induce robust T-and B-cell immune responses and full efficacy in mice
J García-Arriaza, U Garaigorta, P Pérez, A Lázaro-Frías, C Zamora, ...
Journal of virology 95 (7), 10.1128/jvi. 02260-20, 2021
Poxvirus vectors as HIV/AIDS vaccines in humans
C Elena Gomez, B Perdiguero, J García-Arriaza, M Esteban
Human vaccines & immunotherapeutics 8 (9), 1192-1207, 2012
Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1 …
F García, JCLB de Quirós, CE Gómez, B Perdiguero, JL Nájera, ...
Vaccine 29 (46), 8309-8316, 2011
Clinical applications of attenuated MVA poxvirus strain
CE Gómez, B Perdiguero, J García-Arriaza, M Esteban
Expert review of vaccines 12 (12), 1395-1416, 2013
Immunogenic profiling in mice of a HIV/AIDS vaccine candidate (MVA-B) expressing four HIV-1 antigens and potentiation by specific gene deletions
J García-Arriaza, JL Nájera, CE Gómez, COS Sorzano, M Esteban
PLoS One 5 (8), e12395, 2010
Prime-boost immunization strategies against Chikungunya virus
D Hallengärd, FM Lum, BM Kümmerer, A Lulla, V Lulla, J García-Arriaza, ...
Journal of virology 88 (22), 13333-13343, 2014
A candidate HIV/AIDS vaccine (MVA-B) lacking vaccinia virus gene C6L enhances memory HIV-1-specific T-cell responses
J García-Arriaza, JL Nájera, CE Gómez, N Tewabe, COS Sorzano, ...
PLoS One 6 (8), e24244, 2011
Rapid selection in modified BHK-21 cells of a foot-and-mouth disease virus variant showing alterations in cell tropism
C Escarmís, EC Carrillo, M Ferrer, JFG Arriaza, N Lopez, C Tami, ...
Journal of virology 72 (12), 10171-10179, 1998
Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus
P Roques, K Ljungberg, BM Kümmerer, L Gosse, N Dereuddre-Bosquet, ...
JCI insight 2 (6), 2017
Improving adaptive and memory immune responses of an HIV/AIDS vaccine candidate MVA-B by deletion of vaccinia virus genes (C6L and K7R) blocking interferon signaling pathways
J García-Arriaza, P Arnáez, CE Gómez, CÓS Sorzano, M Esteban
PloS one 8 (6), e66894, 2013
Insertion of Vaccinia Virus C7L Host Range Gene into NYVAC-B Genome Potentiates Immune Responses against HIV-1 Antigens
JL Nájera, CE Gómez, J Garcia-Arriaza, CO Sorzano, M Esteban
PLoS one 5 (6), e11406, 2010
Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1
B Mothe, N Climent, M Plana, M Rosàs, JL Jiménez, ...
Journal of Antimicrobial Chemotherapy 70 (6), 1833-1842, 2015
Dynamics of mutation and recombination in a replicating population of complementing, defective viral genomes
J García-Arriaza, S Ojosnegros, M Dávila, E Domingo, C Escarmís
Journal of molecular biology 360 (3), 558-572, 2006
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