Alex Cagan
Alex Cagan
Wellcome Sanger Institute
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Cited by
Cited by
Great ape genetic diversity and population history
J Prado-Martinez, PH Sudmant, JM Kidd, H Li, JL Kelley, ...
Nature 499 (7459), 471-475, 2013
Somatic mutant clones colonize the human esophagus with age
I Martincorena, JC Fowler, A Wabik, ARJ Lawson, F Abascal, MWJ Hall, ...
Science 362 (6417), 911-917, 2018
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors
MD Young, TJ Mitchell, FA Vieira Braga, MGB Tran, BJ Stewart, ...
science 361 (6402), 594-599, 2018
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7
B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira, S Marelli, WT Harvey, ...
Cell reports 35 (13), 2021
Evidence of long-term gene flow and selection during domestication from analyses of Eurasian wild and domestic pig genomes
LAF Frantz, JG Schraiber, O Madsen, HJ Megens, A Cagan, M Bosse, ...
Nature genetics 47 (10), 1141-1148, 2015
Spatiotemporal immune zonation of the human kidney
BJ Stewart, JR Ferdinand, MD Young, TJ Mitchell, KW Loudon, AM Riding, ...
Science 365 (6460), 1461-1466, 2019
Somatic mutation landscapes at single-molecule resolution
F Abascal, LMR Harvey, E Mitchell, ARJ Lawson, SV Lensing, P Ellis, ...
Nature 593 (7859), 405-410, 2021
Extensive heterogeneity in somatic mutation and selection in the human bladder
ARJ Lawson, F Abascal, THH Coorens, Y Hooks, L O’Neill, C Latimer, ...
Science 370 (6512), 75-82, 2020
The mutational landscape of human somatic and germline cells
L Moore, A Cagan, THH Coorens, MDC Neville, R Sanghvi, MA Sanders, ...
Nature 597 (7876), 381-386, 2021
Somatic mutation rates scale with lifespan across mammals
A Cagan, A Baez-Ortega, N Brzozowska, F Abascal, THH Coorens, ...
Nature 604 (7906), 517-524, 2022
Embryonal precursors of Wilms tumor
THH Coorens, TD Treger, R Al-Saadi, L Moore, MGB Tran, TJ Mitchell, ...
Science 366 (6470), 1247-1251, 2019
Epidermal tissue adapts to restrain progenitors carrying clonal p53 mutations
K Murai, G Skrupskelyte, G Piedrafita, M Hall, V Kostiou, SH Ong, T Nagy, ...
Cell stem cell 23 (5), 687-699. e8, 2018
Genetic influences on brain gene expression in rats selected for tameness and aggression
HO Heyne, S Lautenschläger, R Nelson, F Besnier, M Rotival, A Cagan, ...
Genetics 198 (3), 1277-1290, 2014
Evolution of the pygmy phenotype: Evidence of positive selection from genome-wide scans in African, Asian, and Melanesian pygmies
AB Migliano, IG Romero, M Metspalu, M Leavesley, L Pagani, T Antao, ...
Human biology 85 (1-3), 251-284, 2013
Identification of genomic variants putatively targeted by selection during dog domestication
A Cagan, T Blass
BMC evolutionary biology 16 (1), 1-13, 2016
Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing
P Ellis, L Moore, MA Sanders, TM Butler, SF Brunner, H Lee-Six, ...
Nature Protocols 16 (2), 841-871, 2021
Extensive phylogenies of human development inferred from somatic mutations
THH Coorens, L Moore, PS Robinson, R Sanghvi, J Christopher, ...
Nature 597 (7876), 387-392, 2021
Natural selection in the great apes
A Cagan, C Theunert, H Laayouni, G Santpere, M Pybus, F Casals, ...
Molecular biology and evolution 33 (12), 3268-3283, 2016
Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids
N Georgakopoulos, N Prior, B Angres, G Mastrogiovanni, A Cagan, ...
BMC developmental biology 20 (1), 1-20, 2020
Clonal dynamics of haematopoiesis across the human lifespan
E Mitchell, M Spencer Chapman, N Williams, KJ Dawson, N Mende, ...
Nature 606 (7913), 343-350, 2022
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