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Simona-Adriana Manea, Ph.D.
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AP-1–Dependent Transcriptional Regulation of NADPH Oxidase in Human Aortic Smooth Muscle Cells: Role of p22phox Subunit
A Manea, SA Manea, AV Gafencu, M Raicu, M Simionescu
Arteriosclerosis, thrombosis, and vascular biology 28 (5), 878-885, 2008
1392008
Regulation of Nox enzymes expression in vascular pathophysiology: focusing on transcription factors and epigenetic mechanisms
SA Manea, A Constantin, G Manda, S Sasson, A Manea
Redox biology 5, 358-366, 2015
1302015
Regulation of NADPH oxidase subunit p22phox by NF-kB in human aortic smooth muscle cells
A Manea, SA Manea, AV Gafencu, M Raicu
Archives of physiology and biochemistry 113 (4-5), 163-172, 2007
1232007
Human monocytes and macrophages express NADPH oxidase 5; a potential source of reactive oxygen species in atherosclerosis
A Manea, SA Manea, AM Gan, A Constantin, IM Fenyo, M Raicu, ...
Biochemical and Biophysical Research Communications 461 (1), 172-179, 2015
722015
Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes
SA Manea, ML Antonescu, IM Fenyo, M Raicu, M Simionescu, A Manea
Redox biology 16, 332-343, 2018
672018
Pharmacological inhibition of histone deacetylase reduces NADPH oxidase expression, oxidative stress and the progression of atherosclerotic lesions in hypercholesterolemic …
SA Manea, ML Vlad, IM Fenyo, AG Lazar, M Raicu, H Muresian, ...
Redox biology 28, 101338, 2020
582020
C/EBP transcription factors regulate NADPH oxidase in human aortic smooth muscle cells
SA Manea, A Todirita, M Raicu, A Manea
Journal of Cellular and Molecular Medicine 18 (7), 1467-1477, 2014
542014
Positive regulation of NADPH oxidase 5 by proinflammatory-related mechanisms in human aortic smooth muscle cells
A Manea, SA Manea, IC Florea, CM Luca, M Raicu
Free Radical Biology and Medicine 52 (9), 1497-1507, 2012
532012
Inhibition of JAK/STAT signaling pathway prevents high-glucose-induced increase in endothelin-1 synthesis in human endothelial cells
SA Manea, A Manea, C Heltianu
Cell and tissue research 340 (1), 71-79, 2010
522010
The IL‐6 promoter polymorphism is associated with disease activity and disability in systemic sclerosis
R Sfrent‐Cornateanu, C Mihai, S Balan, R Ionescu, E Moldoveanu
Journal of cellular and molecular medicine 10 (4), 890-895, 2006
452006
High-glucose-increased expression and activation of NADPH oxidase in human vascular smooth muscle cells is mediated by 4-hydroxynonenal-activated PPARα and PPARβ/δ
A Manea, SA Manea, A Todirita, IC Albulescu, M Raicu, S Sasson, ...
Cell and tissue research 361 (2), 593-604, 2015
392015
Histone acetyltransferase-dependent pathways mediate upregulation of NADPH oxidase 5 in human macrophages under inflammatory conditions: a potential mechanism of reactive …
ML Vlad, SA Manea, AG Lazar, M Raicu, H Muresian, M Simionescu, ...
Oxidative medicine and cellular longevity 2019, 2019
352019
High glucose-induced increased expression of endothelin-1 in human endothelial cells is mediated by activated CCAAT/enhancer-binding proteins
SA Manea, A Todirita, A Manea
PLoS One 8 (12), e84170, 2013
342013
Identification of gene variants in NOS3, ET-1 and RAS that confer risk and protection against microangiopathy in type 2 diabetic obese subjects
SA Manea, A Robciuc, C Guja, C Heltianu
Biochemical and biophysical research communications 407 (3), 486-490, 2011
252011
Activated histone acetyltransferase p300/CBP-related signalling pathways mediate up-regulation of NADPH oxidase, inflammation, and fibrosis in diabetic kidney
AG Lazar, ML Vlad, A Manea, M Simionescu, SA Manea
Antioxidants 10 (9), 1356, 2021
242021
c-Src tyrosine kinase mediates high glucose-induced endothelin-1 expression
SA Manea, IM Fenyo, A Manea
The International Journal of Biochemistry & Cell Biology 75, 123-130, 2016
152016
Detection of vascular reactive oxygen species in experimental atherosclerosis by high-resolution near-infrared fluorescence imaging using VCAM-1-targeted liposomes entrapping a …
SA Manea, ML Vlad, D Rebleanu, AG Lazar, IM Fenyo, M Calin, ...
Oxidative Medicine and Cellular Longevity 2021, 1-14, 2021
122021
Genetic determinants of microvascular complications in type 1 diabetes
C Heltianu, C Guja, SA Manea
Type 1 diabetes complications, 2011
122011
Endothelin type A receptor mediates endothelin-1-induced upregulation of NADPH oxidase activity in human aortic smooth muscle cells
A Todirita, A Manea, SA Manea
Annals of the Romanian Society for Cell Biology 18 (1), 44, 2013
52013
Correlation of low molecular weight advanced glycation end products and nitric oxide metabolites with chronic complications in type 1 diabetic patients
C Heltianu, SA Manea, C Guja, C Mihai, C Ionescu-Tirgoviste
Open life sciences 3 (3), 243-249, 2008
52008
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Articles 1–20