AP-1–Dependent Transcriptional Regulation of NADPH Oxidase in Human Aortic Smooth Muscle Cells: Role of p22phox Subunit A Manea, SA Manea, AV Gafencu, M Raicu, M Simionescu Arteriosclerosis, thrombosis, and vascular biology 28 (5), 878-885, 2008 | 139 | 2008 |
Regulation of Nox enzymes expression in vascular pathophysiology: focusing on transcription factors and epigenetic mechanisms SA Manea, A Constantin, G Manda, S Sasson, A Manea Redox biology 5, 358-366, 2015 | 130 | 2015 |
Regulation of NADPH oxidase subunit p22phox by NF-kB in human aortic smooth muscle cells A Manea, SA Manea, AV Gafencu, M Raicu Archives of physiology and biochemistry 113 (4-5), 163-172, 2007 | 123 | 2007 |
Human monocytes and macrophages express NADPH oxidase 5; a potential source of reactive oxygen species in atherosclerosis A Manea, SA Manea, AM Gan, A Constantin, IM Fenyo, M Raicu, ... Biochemical and Biophysical Research Communications 461 (1), 172-179, 2015 | 72 | 2015 |
Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes SA Manea, ML Antonescu, IM Fenyo, M Raicu, M Simionescu, A Manea Redox biology 16, 332-343, 2018 | 67 | 2018 |
Pharmacological inhibition of histone deacetylase reduces NADPH oxidase expression, oxidative stress and the progression of atherosclerotic lesions in hypercholesterolemic … SA Manea, ML Vlad, IM Fenyo, AG Lazar, M Raicu, H Muresian, ... Redox biology 28, 101338, 2020 | 58 | 2020 |
C/EBP transcription factors regulate NADPH oxidase in human aortic smooth muscle cells SA Manea, A Todirita, M Raicu, A Manea Journal of Cellular and Molecular Medicine 18 (7), 1467-1477, 2014 | 54 | 2014 |
Positive regulation of NADPH oxidase 5 by proinflammatory-related mechanisms in human aortic smooth muscle cells A Manea, SA Manea, IC Florea, CM Luca, M Raicu Free Radical Biology and Medicine 52 (9), 1497-1507, 2012 | 53 | 2012 |
Inhibition of JAK/STAT signaling pathway prevents high-glucose-induced increase in endothelin-1 synthesis in human endothelial cells SA Manea, A Manea, C Heltianu Cell and tissue research 340 (1), 71-79, 2010 | 52 | 2010 |
The IL‐6 promoter polymorphism is associated with disease activity and disability in systemic sclerosis R Sfrent‐Cornateanu, C Mihai, S Balan, R Ionescu, E Moldoveanu Journal of cellular and molecular medicine 10 (4), 890-895, 2006 | 45 | 2006 |
High-glucose-increased expression and activation of NADPH oxidase in human vascular smooth muscle cells is mediated by 4-hydroxynonenal-activated PPARα and PPARβ/δ A Manea, SA Manea, A Todirita, IC Albulescu, M Raicu, S Sasson, ... Cell and tissue research 361 (2), 593-604, 2015 | 39 | 2015 |
Histone acetyltransferase-dependent pathways mediate upregulation of NADPH oxidase 5 in human macrophages under inflammatory conditions: a potential mechanism of reactive … ML Vlad, SA Manea, AG Lazar, M Raicu, H Muresian, M Simionescu, ... Oxidative medicine and cellular longevity 2019, 2019 | 35 | 2019 |
High glucose-induced increased expression of endothelin-1 in human endothelial cells is mediated by activated CCAAT/enhancer-binding proteins SA Manea, A Todirita, A Manea PLoS One 8 (12), e84170, 2013 | 34 | 2013 |
Identification of gene variants in NOS3, ET-1 and RAS that confer risk and protection against microangiopathy in type 2 diabetic obese subjects SA Manea, A Robciuc, C Guja, C Heltianu Biochemical and biophysical research communications 407 (3), 486-490, 2011 | 25 | 2011 |
Activated histone acetyltransferase p300/CBP-related signalling pathways mediate up-regulation of NADPH oxidase, inflammation, and fibrosis in diabetic kidney AG Lazar, ML Vlad, A Manea, M Simionescu, SA Manea Antioxidants 10 (9), 1356, 2021 | 24 | 2021 |
c-Src tyrosine kinase mediates high glucose-induced endothelin-1 expression SA Manea, IM Fenyo, A Manea The International Journal of Biochemistry & Cell Biology 75, 123-130, 2016 | 15 | 2016 |
Detection of vascular reactive oxygen species in experimental atherosclerosis by high-resolution near-infrared fluorescence imaging using VCAM-1-targeted liposomes entrapping a … SA Manea, ML Vlad, D Rebleanu, AG Lazar, IM Fenyo, M Calin, ... Oxidative Medicine and Cellular Longevity 2021, 1-14, 2021 | 12 | 2021 |
Genetic determinants of microvascular complications in type 1 diabetes C Heltianu, C Guja, SA Manea Type 1 diabetes complications, 2011 | 12 | 2011 |
Endothelin type A receptor mediates endothelin-1-induced upregulation of NADPH oxidase activity in human aortic smooth muscle cells A Todirita, A Manea, SA Manea Annals of the Romanian Society for Cell Biology 18 (1), 44, 2013 | 5 | 2013 |
Correlation of low molecular weight advanced glycation end products and nitric oxide metabolites with chronic complications in type 1 diabetic patients C Heltianu, SA Manea, C Guja, C Mihai, C Ionescu-Tirgoviste Open life sciences 3 (3), 243-249, 2008 | 5 | 2008 |