| Nitrosative stress drives heart failure with preserved ejection fraction GG Schiattarella, F Altamirano, D Tong, KM French, E Villalobos, SY Kim, ... Nature 568 (7752), 351-356, 2019 | 578 | 2019 |
| Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease DI Lee, G Zhu, T Sasaki, GS Cho, N Hamdani, R Holewinski, SH Jo, ... Nature 519 (7544), 472-476, 2015 | 339 | 2015 |
| Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy K Seo, PP Rainer, V Shalkey Hahn, D Lee, SH Jo, A Andersen, T Liu, ... Proceedings of the National Academy of Sciences 111 (4), 1551-1556, 2014 | 206 | 2014 |
| Transcriptional landscape of cardiomyocyte maturation H Uosaki, P Cahan, DI Lee, S Wang, M Miyamoto, L Fernandez, DA Kass, ... Cell reports 13 (8), 1705-1716, 2015 | 164 | 2015 |
| Muc1 mucins on the cell surface are adhesion sites forPseudomonas aeruginosa EP Lillehoj, SW Hyun, BT Kim, XG Zhang, DI Lee, S Rowland, KC Kim American Journal of Physiology-Lung Cellular and Molecular Physiology 280 (1 …, 2001 | 145 | 2001 |
| Phospholamban thiols play a central role in activation of the cardiac muscle sarcoplasmic reticulum calcium pump by nitroxyl JP Froehlich, JE Mahaney, G Keceli, CM Pavlos, R Goldstein, ... Biochemistry 47 (50), 13150-13152, 2008 | 119 | 2008 |
| NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction D Tong, GG Schiattarella, N Jiang, F Altamirano, PA Szweda, ... Circulation research 128 (11), 1629-1641, 2021 | 110 | 2021 |
| PDE5A suppression of acute β-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation DI Lee, S Vahebi, CG Tocchetti, LA Barouch, RJ Solaro, E Takimoto, ... Basic research in cardiology 105, 337-347, 2010 | 109 | 2010 |
| Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway Q He, DI Lee, R Rong, M Yu, X Luo, M Klein, WS El-Deiry, Y Huang, ... Oncogene 21 (17), 2623-2633, 2002 | 107 | 2002 |
| PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress MJ Ranek, KM Kokkonen-Simon, A Chen, BL Dunkerly-Eyring, MP Vera, ... Nature 566 (7743), 264-269, 2019 | 106 | 2019 |
| Neonatal transplantation confers maturation of PSC-derived cardiomyocytes conducive to modeling cardiomyopathy GS Cho, DI Lee, E Tampakakis, S Murphy, P Andersen, H Uosaki, ... Cell reports 18 (2), 571-582, 2017 | 103 | 2017 |
| Cardiomyocyte-specific transforming growth factor β suppression blocks neutrophil infiltration, augments multiple cytoprotective cascades, and reduces early mortality after … PP Rainer, S Hao, D Vanhoutte, DI Lee, N Koitabashi, JD Molkentin, ... Circulation research 114 (8), 1246-1257, 2014 | 99 | 2014 |
| Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5 M Zhang, E Takimoto, S Hsu, DI Lee, T Nagayama, T Danner, ... Journal of the American College of Cardiology 56 (24), 2021-2030, 2010 | 98 | 2010 |
| Hyperactive adverse mechanical stress responses in dystrophic heart are coupled to transient receptor potential canonical 6 and blocked by cGMP–protein kinase G modulation K Seo, PP Rainer, D Lee, S Hao, D Bedja, L Birnbaumer, OH Cingolani, ... Circulation research 114 (5), 823-832, 2014 | 93 | 2014 |
| Divergent effects of miR‐181 family members on myocardial function through protective cytosolic and detrimental mitochondrial microRNA targets S Das, M Kohr, B Dunkerly‐Eyring, DI Lee, D Bedja, OA Kent, AKL Leung, ... Journal of the American Heart Association 6 (3), e004694, 2017 | 90 | 2017 |
| Thrombospondin-4 is required for stretch-mediated contractility augmentation in cardiac muscle OH Cingolani, JA Kirk, K Seo, N Koitabashi, D Lee, G Ramirez-Correa, ... Circulation research 109 (12), 1410-1414, 2011 | 89 | 2011 |
| HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization V Sivakumaran, BA Stanley, CG Tocchetti, JD Ballin, V Caceres, L Zhou, ... Antioxidants & redox signaling 19 (11), 1185-1197, 2013 | 86 | 2013 |
| PDE5 inhibitor efficacy is estrogen dependent in female heart disease H Sasaki, T Nagayama, RM Blanton, K Seo, M Zhang, G Zhu, DI Lee, ... The Journal of clinical investigation 124 (6), 2464-2471, 2014 | 79 | 2014 |
| Prevention of PKG1α oxidation augments cardioprotection in the stressed heart T Nakamura, MJ Ranek, DI Lee, VS Hahn, C Kim, P Eaton, DA Kass The Journal of clinical investigation 125 (6), 2468-2472, 2015 | 77 | 2015 |
| Phosphodiesterases and cyclic GMP regulation in heart muscle DI Lee, DA Kass Physiology 27 (4), 248-258, 2012 | 75 | 2012 |
David A. KassJohns Hopkins UniversityVerified email at jhmi.edu
