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Prakash Manikwar
Prakash Manikwar
Scientist
Verified email at medimmune.com
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Cited by
Year
Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody
R Majumdar, P Manikwar, JM Hickey, HS Samra, HA Sathish, SM Bishop, ...
Biochemistry 52 (19), 3376-3389, 2013
1152013
Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass†…
P Manikwar, R Majumdar, JM Hickey, SV Thakkar, HS Samra, HA Sathish, ...
Journal of pharmaceutical sciences 102 (7), 2136-2151, 2013
972013
Analytical lessons learned from selected therapeutic protein drug comparability studies
M Federici, A Lubiniecki, P Manikwar, DB Volkin
Biologicals 41 (3), 131-147, 2013
772013
Minimizing carry-over in an online pepsin digestion system used for the H/D exchange mass spectrometric analysis of an IgG1 monoclonal antibody
R Majumdar, P Manikwar, JM Hickey, J Arora, CR Middaugh, DB Volkin, ...
Journal of the American Society for Mass Spectrometry 23 (12), 2140-2148, 2012
712012
cIBR effectively targets nanoparticles to LFA-1 on acute lymphoblastic T cells
C Chittasupho, P Manikwar, JP Krise, TJ Siahaan, C Berkland
Molecular pharmaceutics 7 (1), 146-155, 2010
472010
Antigen‐specific blocking of CD4‐specific immunological synapse formation using BPI and current therapies for autoimmune diseases
P Manikwar, P Kiptoo, AH Badawi, B BŁyŁktimkin, TJ Siahaan
Medicinal research reviews 32 (4), 727-764, 2012
352012
Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions
PS Sarangapani, J Weaver, A Parupudi, TMD Besong, GG Adams, ...
Journal of pharmaceutical sciences 105 (12), 3496-3506, 2016
262016
Rapid identification of fluorochrome modification sites in proteins by LC ESI-Q-TOF mass spectrometry
P Manikwar, T Zimmerman, FJ Blanco, TD Williams, TJ Siahaan
Bioconjugate chemistry 22 (7), 1330-1336, 2011
192011
Mechanism of a decrease in potency for the recombinant influenza A virus hemagglutinin H3 antigen during storage
JM Hickey, KM Holtz, P Manikwar, SB Joshi, CE Mcpherson, B Buckland, ...
Journal of pharmaceutical sciences 103 (3), 821-827, 2014
162014
Utilization of I-domain of LFA-1 to Target Drug and Marker Molecules to Leukocytes
P Manikwar, BA Tejo, H Shinogle, DS Moore, T Zimmerman, F Blanco, ...
Theranostics 1, 277, 2011
162011
Characterization of a novel bispecific antibody with improved conformational and chemical stability
P Manikwar, SHR Mulagapati, S Kasturirangan, K Moez, GJ Rainey, ...
Journal of Pharmaceutical Sciences 109 (1), 220-232, 2020
142020
I-domain-antigen conjugate (IDAC) for delivering antigenic peptides to APC: synthesis, characterization, and in vivo EAE suppression
P Manikwar, B Büyüktimkin, P Kiptoo, AH Badawi, NA Galeva, ...
Bioconjugate chemistry 23 (3), 509-517, 2012
92012
Vaccinelike and prophylactic treatments of EAE with novel I-domain antigen conjugates (IDAC): targeting multiple antigenic peptides to APC
B Büyüktimkin, P Manikwar, PK Kiptoo, AH Badawi, JM Stewart Jr, ...
Molecular pharmaceutics 10 (1), 297-306, 2013
62013
Bispecific binding proteins and uses thereof
S Kasturirangan, C Gao, G Rainey, M Morrow, CL Dobson, S Drabic, ...
US Patent 10,457,732, 2019
42019
Preformulation characterization, stabilization, and formulation design for the acrylodan-labeled glucose-binding protein SM4-AC
N Sahni, R Chaudhuri, JM Hickey, P Manikwar, A D’Souza, A Metters, ...
Journal of Pharmaceutical Sciences 106 (5), 1197-1210, 2017
42017
Sensitivity and Uncertainty Analysis of Micro-Flow Imaging for Sub-Visible Particle Measurements Using Artificial Neural Network
S Poozesh, F CannavÚ, P Manikwar
Pharmaceutical Research 40 (3), 721-733, 2023
12023
Bispecific binding proteins and uses thereof
S Kasturirangan, C Gao, G Rainey, M Morrow, CL Dobson, S Drabic, ...
12020
Rapid Room-Temperature Aerosol Dehydration Versus Spray Drying: A Novel Paradigm in Biopharmaceutical Drying Technologies
S Poozesh, M Mezhericher, Z Pan, U Chaudhary, P Manikwar, HA Stone
Journal of Pharmaceutical Sciences, 2023
2023
Dry Powder Formulations of Thymic Stromal Lymphopoietin (TSLP)-Binding Antibodies and Methods of Use Thereof
CEC Huntington, HOE Susan, P Manikwar, RW Kolbeck, ES Cohen, ...
US Patent App. 18/053,941, 2023
2023
Dry powder formulations containing leucine and trileucine
P Manikwar, D Lechuga-Ballesteros, HOE Susan, KB Hansen, DJ D'sa, ...
US Patent App. 17/772,187, 2022
2022
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