Structural basis for gluten intolerance in celiac sprue L Shan, Ø Molberg, I Parrot, F Hausch, F Filiz, GM Gray, LM Sollid, ... Science 297 (5590), 2275-2279, 2002 | 1955 | 2002 |
A new enzyme superfamily—the phosphopantetheinyl transferases RH Lambalot, AM Gehring, RS Flugel, P Zuber, M LaCelle, MA Marahiel, ... Chemistry & biology 3 (11), 923-936, 1996 | 1056 | 1996 |
Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli BA Pfeifer, SJ Admiraal, H Gramajo, DE Cane, C Khosla Science 291 (5509), 1790-1792, 2001 | 885 | 2001 |
Harnessing the biosynthetic code: combinations, permutations, and mutations DE Cane, CT Walsh, C Khosla Science 282 (5386), 63-68, 1998 | 847 | 1998 |
Engineered biosynthesis of novel polyketides R McDaniel, S Ebert-Khosla, DA Hopwood, C Khosla Science 262 (5139), 1546-1550, 1993 | 598 | 1993 |
Cloning and heterologous expression of the epothilone gene cluster L Tang, S Shah, L Chung, J Carney, L Katz, C Khosla, B Julien Science 287 (5453), 640-642, 2000 | 551 | 2000 |
Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease CY Kim, H Quarsten, E Bergseng, C Khosla, LM Sollid Proceedings of the National Academy of Sciences 101 (12), 4175-4179, 2004 | 506 | 2004 |
Transglutaminase 2 undergoes a large conformational change upon activation DM Pinkas, P Strop, AT Brunger, C Khosla PLoS biology 5 (12), e327, 2007 | 483 | 2007 |
Overproduction of free fatty acids in E. coli: implications for biodiesel production X Lu, H Vora, C Khosla Metabolic engineering 10 (6), 333-339, 2008 | 472 | 2008 |
Tolerance and specificity of polyketide synthases C Khosla, RS Gokhale, JR Jacobsen, DE Cane Annual review of biochemistry 68 (1), 219-253, 1999 | 461 | 1999 |
Intestinal digestive resistance of immunodominant gliadin peptides F Hausch, L Shan, NA Santiago, GM Gray, C Khosla American Journal of Physiology-Gastrointestinal and Liver Physiology, 2002 | 453 | 2002 |
Dissecting and exploiting intermodular communication in polyketide synthases RS Gokhale, SY Tsuji, DE Cane, C Khosla Science 284 (5413), 482-485, 1999 | 416 | 1999 |
Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease R Bouziat, R Hinterleitner, JJ Brown, JE Stencel-Baerenwald, M Ikizler, ... Science 356 (6333), 44-50, 2017 | 385 | 2017 |
Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase JR Jacobsen, CR Hutchinson, DE Cane, C Khosla Science 277 (5324), 367-369, 1997 | 377 | 1997 |
Biosynthesis of polyketides in heterologous hosts BA Pfeifer, C Khosla Microbiology and Molecular Biology Reviews 65 (1), 106-118, 2001 | 367 | 2001 |
Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits R McDaniel, S Ebert-Khosla, DA Hopwood, C Khosla Nature 375 (6532), 549-554, 1995 | 358 | 1995 |
Engineered biosynthesis of a complete macrolactone in a heterologous host CM Kao, L Katz, C Khosla Science 265 (5171), 509-512, 1994 | 344 | 1994 |
Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue L Shan, SW Qiao, H Arentz-Hansen, Ø Molberg, GM Gray, LM Sollid, ... Journal of proteome research 4 (5), 1732-1741, 2005 | 340 | 2005 |
Heterologous expression of a bacterial haemoglobin improves the growth properties of recombinant Escherichia coli C Khosla, JE Bailey Nature 331 (6157), 633-635, 1988 | 332 | 1988 |
Structure and mechanism of the 6-deoxyerythronolide B synthase C Khosla, Y Tang, AY Chen, NA Schnarr, DE Cane Annu. Rev. Biochem. 76, 195-221, 2007 | 323 | 2007 |