| Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents C Oliveira, D Bagetta, F Cagide, J Teixeira, R Amorim, T Silva, J Garrido, ... European journal of medicinal chemistry 174, 116-129, 2019 | 45 | 2019 |
| Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative J Teixeira, R Amorim, K Santos, P Soares, S Datta, GA Cortopassi, ... Toxicology 393, 123-139, 2018 | 41 | 2018 |
| Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction S Benfeito, C Oliveira, C Fernandes, F Cagide, J Teixeira, R Amorim, ... European journal of medicinal chemistry 167, 525-545, 2019 | 37 | 2019 |
| Hydroxybenzoic acid derivatives as dual-target ligands: mitochondriotropic antioxidants and cholinesterase inhibitors C Oliveira, F Cagide, J Teixeira, R Amorim, L Sequeira, F Mesiti, T Silva, ... Frontiers in chemistry 6, 126, 2018 | 37 | 2018 |
| Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria J Teixeira, C Oliveira, R Amorim, F Cagide, J Garrido, JA Ribeiro, ... Scientific reports 7 (1), 6842, 2017 | 37 | 2017 |
| The alterations of mitochondrial function during NAFLD progression—an independent effect of mitochondrial ROS production ICM Simões, R Amorim, J Teixeira, A Karkucinska-Wieckowska, ... International journal of molecular sciences 22 (13), 6848, 2021 | 30 | 2021 |
| Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid J Teixeira, C Oliveira, F Cagide, R Amorim, J Garrido, F Borges, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 567-576, 2018 | 25 | 2018 |
| Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts J Teixeira, F Basit, PHGM Willems, JA Wagenaars, E van de Westerlo, ... Free Radical Biology and Medicine 163, 314-324, 2021 | 18 | 2021 |
| Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress … R Amorim, F Cagide, LC Tavares, RF Simões, P Soares, S Benfeito, ... Free Radical Biology and Medicine 179, 119-132, 2022 | 16 | 2022 |
| Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation … R Amorim, ICM Simões, J Teixeira, F Cagide, Y Potes, P Soares, ... Redox Biology 55, 102400, 2022 | 14 | 2022 |
| Desrisking the cytotoxicity of a Mitochondriotropic antioxidant based on Caffeic acid by a PEGylated strategy C Fernandes, S Benfeito, R Amorim, J Teixeira, PJ Oliveira, F Remiao, ... Bioconjugate chemistry 29 (8), 2723-2733, 2018 | 14 | 2018 |
| RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease MB Afonso, T Islam, J Magusto, R Amorim, V Lenoir, RF Simões, ... Hepatology 77 (4), 1319-1334, 2023 | 12 | 2023 |
| Targeting mitochondria: the road to mitochondriotropic antioxidants and beyond R Amorim, S Benfeito, J Teixeira, F Cagide, PJ Oliveira, F Borges Mitochondrial biology and experimental therapeutics, 333-358, 2018 | 11 | 2018 |
| Exploratory data analysis of cell and mitochondrial high-fat, high-sugar toxicity on human HepG2 cells R Amorim, ICM Simões, C Veloso, A Carvalho, RF Simões, FB Pereira, ... Nutrients 13 (5), 1723, 2021 | 10 | 2021 |
| From non-alcoholic fatty liver to hepatocellular carcinoma: a story of (mal) adapted mitochondria R Amorim, CC Magalhães, F Borges, PJ Oliveira, J Teixeira Biology 12 (4), 595, 2023 | 5 | 2023 |
| Decreasing the toxicity of paraquat through the complexation with sodium salicylate: Stoichiometric analysis L Gales, R Amorim, CMM Afonso, F Carvalho, RJ Dinis-Oliveira Toxicology 336, 96-98, 2015 | 4 | 2015 |
| Trombose do Seio Cavernoso em Criança de 4 anos com Sinusite–Complicações Oculares ML Colaço, A Silva, F Bráz, M Franco, R Amorim, T Silva, JM Sêco Revista Sociedade Portuguesa de Oftalmologia 37 (1), 2013 | 1 | 2013 |
| Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes cisplatin lung anticancer therapy due to a remodeling … R Amorim, CC Magalhães, S Benfeito, F Cagide, LC Tavares, K Santos, ... Biochemical Pharmacology 219, 115953, 2024 | | 2024 |
| Mitochondriotropic antioxidant AntiOxCIN4 improves mitochondrial function and prevents non-alcoholic fatty liver (NAFL)-associated autophagic blockage in western diet (WD)-fed mice R Amorim, ICM Simoes, J Teixeira, P Soares, Y Potes, F Cagide, ... EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 52, 2022 | | 2022 |
| Mitochondriotropic Antioxidants Based on Hydroxycinnamic Acids Activates Nrf2-Mediated Cell Signalling Responses to Oxidative Stress: Implications in Non-Alcoholic Fatty Liver … J Teixeira, R Amorim, I Simoes, F Cagide, Y Potes, P Soares, S Benfeito, ... EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 52, 2022 | | 2022 |
