Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ... The Lancet 397 (10269), 99-111, 2021 | 5704 | 2021 |
Inflammation induced by influenza virus impairs human innate immune control of pneumococcus SP Jochems, F Marcon, BF Carniel, M Holloway, E Mitsi, E Smith, ... Nature immunology 19 (12), 1299-1308, 2018 | 172 | 2018 |
Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state E Mitsi, R Kamng’ona, J Rylance, C Solórzano, J Jesus Reiné, ... Respiratory research 19, 1-4, 2018 | 128 | 2018 |
Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage E Mitsi, AM Roche, J Reiné, T Zangari, JT Owugha, SH Pennington, ... Mucosal immunology 10 (2), 385-394, 2017 | 106 | 2017 |
Novel analysis of immune cells from nasal microbiopsy demonstrates reliable, reproducible data for immune populations, and superior cytokine detection compared to nasal wash SP Jochems, K Piddock, J Rylance, H Adler, BF Carniel, A Collins, ... PloS one 12 (1), e0169805, 2017 | 76 | 2017 |
A leaky mutation in CD3D differentially affects αβ and γδ T cells and leads to a Tαβ–Tγδ+B+NK+ human SCID J Gil, EM Busto, B Garcillán, C Chean, MC García-Rodríguez, ... The Journal of Clinical Investigation 121 (10), 3872-3876, 2011 | 65 | 2011 |
Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface CM Weight, C Venturini, S Pojar, SP Jochems, J Reiné, E Nikolaou, ... Nature communications 10 (1), 3060, 2019 | 61 | 2019 |
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization SP Jochems, K de Ruiter, C Solórzano, A Voskamp, E Mitsi, E Nikolaou, ... The Journal of clinical investigation 129 (10), 2022 | 57 | 2022 |
Streptococcus pneumoniae colonization associates with impaired adaptive immune responses against SARS-CoV-2 E Mitsi, J Reiné, BC Urban, C Solórzano, E Nikolaou, AD Hyder-Wright, ... The Journal of clinical investigation 132 (7), 2022 | 46 | 2022 |
Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine BF Carniel, F Marcon, J Rylance, EL German, S Zaidi, J Reiné, E Negera, ... JCI insight 6 (4), 2021 | 44 | 2021 |
Nasal pneumococcal density is associated with microaspiration and heightened human alveolar macrophage responsiveness to bacterial pathogens E Mitsi, B Carniel, J Reiné, J Rylance, S Zaidi, A Soares-Schanoski, ... American Journal of Respiratory and Critical Care Medicine 201 (3), 335-347, 2020 | 44 | 2020 |
Single use and conventional bronchoscopes for Broncho alveolar lavage (BAL) in research: a comparative study (NCT 02515591) SR Zaidi, AM Collins, E Mitsi, J Reiné, K Davies, AD Wright, J Owugha, ... BMC pulmonary medicine 17, 1-5, 2017 | 43 | 2017 |
Two randomized trials of the effect of live attenuated influenza vaccine on pneumococcal colonization J Rylance, WAA de Steenhuijsen Piters, MJ Mina, D Bogaert, N French, ... American journal of respiratory and critical care medicine 199 (9), 1160-1163, 2019 | 34 | 2019 |
Differential antibody binding to the surface αβTCR·CD3 complex of CD4+ and CD8+ T lymphocytes is conserved in mammals and associated with differential … NE Rossi, J Reiné, M Pineda-Lezamit, M Pulgar, NW Meza, M Swamy, ... International immunology 20 (10), 1247-1258, 2008 | 33 | 2008 |
Experimental human pneumococcal colonization in older adults is feasible and safe, not immunogenic H Adler, EL German, E Mitsi, E Nikolaou, S Pojar, C Hales, R Robinson, ... American journal of respiratory and critical care medicine 203 (5), 604-613, 2021 | 29 | 2021 |
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination E Mitsi, MO Diniz, J Reiné, AM Collins, RE Robinson, A Hyder-Wright, ... Nature Communications 14 (1), 6815, 2023 | 28 | 2023 |
Experimental human challenge defines distinct pneumococcal kinetic profiles and mucosal responses between colonized and non-colonized adults E Nikolaou, SP Jochems, E Mitsi, S Pojar, A Blizard, J Reiné, C Solórzano, ... MBio 12 (1), 10.1128/mbio. 02020-20, 2021 | 21 | 2021 |
Augmented passive immunotherapy with P4 peptide improves phagocyte activity in severe sepsis B Morton, E Mitsi, SH Pennington, J Reiné, AD Wright, R Parker, ... Shock 46 (6), 635-641, 2016 | 21 | 2016 |
Intrapulmonary pharmacokinetics of cefepime and enmetazobactam in healthy volunteers: towards new treatments for nosocomial pneumonia S Das, R Fitzgerald, A Ullah, M Bula, AM Collins, E Mitsi, J Reine, H Hill, ... Antimicrobial Agents and Chemotherapy 65 (1), 10.1128/aac. 01468-20, 2020 | 18 | 2020 |
Nonspecific effects of oral vaccination with live-attenuated Salmonella Typhi strain Ty21a SH Pennington, DM Ferreira, E Caamaño-Gutiérrez, J Reiné, C Hewitt, ... Science Advances 5 (2), eaau6849, 2019 | 15 | 2019 |