| Rapid detection of octamer binding proteins with'mini-extracts', prepared from a small number of cells. E Schreiber, P Matthias, MM Müller, W Schaffner Nucleic acids research 17 (15), 6419, 1989 | 4840 | 1989 |
| A rapid, sensitive, and specific method for the determination of protein in dilute solution W Schaffner, C Weissmann Analytical biochemistry 56 (2), 502-514, 1973 | 2948 | 1973 |
| Expression of a β-globin gene is enhanced by remote SV40 DNA sequences J Banerji, S Rusconi, W Schaffner Cell 27 (2), 299-308, 1981 | 2206 | 1981 |
| A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus M Boshart, F Weber, G Jahn, K Dorsch-H, B Fleckenstein, W Schaffner cell 41 (2), 521-530, 1985 | 1785 | 1985 |
| A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes J Banerji, L Olson, W Schaffner Cell 33 (3), 729-740, 1983 | 1781 | 1983 |
| Transcriptional activation modulated by homopolymeric glutamine and proline stretches HP Gerber, K Seipel, O Georgiev, M Höfferer, M Hug, S Rusconi, ... Science 263 (5148), 808-811, 1994 | 772 | 1994 |
| CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. SM Iguchi-Ariga, W Schaffner Genes & development 3 (5), 612-619, 1989 | 749 | 1989 |
| Enhancers and eukaryotic gene transcription E Serfling, M Jasin, W Schaffner Trends in Genetics 1, 224-230, 1985 | 731 | 1985 |
| The transcription factor MTF‐1 is essential for basal and heavy metal‐induced metallothionein gene expression. R Heuchel, F Radtke, O Georgiev, G Stark, M Aguet, W Schaffner The EMBO journal 13 (12), 2870-2875, 1994 | 603 | 1994 |
| A cloned octamer transcription factor stimulates transcription from lymphoid–specific promoters in non–B cells MM Müller, S Ruppert, W Schaffner, P Matthias Nature 336 (6199), 544-551, 1988 | 506 | 1988 |
| Cloned transcription factor MTF‐1 activates the mouse metallothionein I promoter. F Radtke, R Heuchel, O Georgiev, M Hergersberg, M Gariglio, Z Dembic, ... The EMBO journal 12 (4), 1355-1362, 1993 | 463 | 1993 |
| A lymphocyte-specific enhancer in the mouse immunoglobulin κ gene D Picard, W Schaffner Nature 307 (5946), 80-82, 1984 | 446 | 1984 |
| Different activation domains stimulate transcription from remote (‘enhancer’) and proximal (‘promoter’) positions. K Seipel, O Georgiev, W Schaffner The EMBO journal 11 (13), 4961-4968, 1992 | 436 | 1992 |
| Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated. M Höller, G Westin, J Jiricny, W Schaffner Genes & development 2 (9), 1127-1135, 1988 | 407 | 1988 |
| A small segment of polyoma virus DNA enhances the expression of a cloned β-globin gene over a distance of 1400 base pairs J de Villiers, W Schaffner Nucleic acids research 9 (23), 6251-6264, 1981 | 400 | 1981 |
| Molecular genetic analyses of the Tyrolean Ice Man O Handt, M Richards, M Trommsdorff, C Kilger, J Simanainen, O Georgiev, ... Science 264 (5166), 1775-1778, 1994 | 386 | 1994 |
| Direct transfer of cloned genes from bacteria to mammalian cells. W Schaffner Proceedings of the National Academy of Sciences 77 (4), 2163-2167, 1980 | 382 | 1980 |
| The taste of heavy metals: gene regulation by MTF-1 V Günther, U Lindert, W Schaffner Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (9), 1416-1425, 2012 | 371 | 2012 |
| A B-cell coactivator of octamer-binding transcription factors M Gstaiger, L Knoepfel, O Georgiev, W Schaffner, CM Hovens Nature 373 (6512), 360-362, 1995 | 364 | 1995 |
| DNA phylogeny of the extinct marsupial wolf RH Thomas, W Schaffner, AC Wilson, S Pääbo Nature 340 (6233), 465-467, 1989 | 363 | 1989 |
