Kevin C. O'Connor
Kevin C. O'Connor
Professor of Neurology and Immunobiology, Yale University
Verified email at
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MRI characteristics of neuromyelitis optica spectrum disorder: an international update
HJ Kim, F Paul, MA Lana-Peixoto, S Tenembaum, N Asgari, J Palace, ...
Neurology 84 (11), 1165-1173, 2015
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes
JNH Stern, G Yaari, JA Vander Heiden, G Church, WF Donahue, ...
Science translational medicine 6 (248), 248ra107-248ra107, 2014
Comprehensive serological profiling of human populations using a synthetic human virome
GJ Xu, T Kula, Q Xu, MZ Li, SD Vernon, T Ndung’u, K Ruxrungtham, ...
Science 348 (6239), aaa0698, 2015
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires
JA Vander Heiden, G Yaari, M Uduman, JNH Stern, KC O’connor, ...
Bioinformatics 30 (13), 1930-1932, 2014
Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein
KC O'Connor, KA McLaughlin, PL De Jager, T Chitnis, E Bettelli, C Xu, ...
Nature medicine 13 (2), 211-217, 2007
MOG cell-based assay detects non-MS patients with inflammatory neurologic disease
P Waters, M Woodhall, KC O'Connor, M Reindl, B Lang, DK Sato, ...
Neuroimmunology & Neuroinflammation 2 (3), e89, 2015
Imaging robust microglial activation after lipopolysaccharide administration in humans with PET
CM Sandiego, JD Gallezot, B Pittman, N Nabulsi, K Lim, SF Lin, ...
Proceedings of the National Academy of Sciences 112 (40), 12468-12473, 2015
Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain
SN Willis, C Stadelmann, SJ Rodig, T Caron, S Gattenloehner, ...
Brain 132 (12), 3318-3328, 2009
Dysregulated T cell expression of TIM3 in multiple sclerosis
K Koguchi, DE Anderson, L Yang, KC O'Connor, VK Kuchroo, DA Hafler
The Journal of experimental medicine 203 (6), 1413-1418, 2006
The neuroimmunology of multiple sclerosis: possible roles of T and B lymphocytes in immunopathogenesis
KC O'connor, A Bar-Or, DA Hafler
Journal of clinical immunology 21, 81-92, 2001
Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis
L Lovato, SN Willis, SJ Rodig, T Caron, SE Almendinger, OW Howell, ...
Brain 134 (2), 534-541, 2011
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data
G Yaari, JA Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ...
Frontiers in immunology 4, 358, 2013
Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid
GP Owens, JL Bennett, H Lassmann, KC O'Connor, AM Ritchie, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis
KA McLaughlin, T Chitnis, J Newcombe, B Franz, J Kennedy, S McArdel, ...
The Journal of Immunology 183 (6), 4067-4076, 2009
Antibodies from inflamed central nervous system tissue recognize myelin oligodendrocyte glycoprotein
KC O’Connor, H Appel, L Bregoli, ME Call, I Catz, JA Chan, NH Moore, ...
The Journal of Immunology 175 (3), 1974-1982, 2005
Plasma cells in muscle in inclusion body myositis and polymyositis
SA Greenberg, EM Bradshaw, JL Pinkus, GS Pinkus, T Burleson, B Due, ...
Neurology 65 (11), 1782-1787, 2005
The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: a [11C] PBR28 PET study
J Hannestad, N DellaGioia, JD Gallezot, K Lim, N Nabulsi, I Esterlis, ...
Brain, behavior, and immunity 33, 131-138, 2013
Autoantibodies frequently detected in patients with aplastic anemia
N Hirano, MO Butler, MS von Bergwelt-Baildon, B Maecker, JL Schultze, ...
Blood 102 (13), 4567-4575, 2003
Specific peripheral B cell tolerance defects in patients with multiple sclerosis
T Kinnunen, N Chamberlain, H Morbach, T Cantaert, M Lynch, ...
The Journal of clinical investigation 123 (6), 2737-2741, 2013
A local antigen-driven humoral response is present in the inflammatory myopathies
EM Bradshaw, A Orihuela, SL McArdel, M Salajegheh, AA Amato, ...
The Journal of Immunology 178 (1), 547-556, 2007
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