| The role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise J Jensen, PI Rustad, AJ Kolnes, YC Lai Frontiers in physiology 2, 112, 2011 | 508 | 2011 |
| Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ... Cell reports 28 (7), 1717-1728. e6, 2019 | 304 | 2019 |
| Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1 YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ... The EMBO journal 34 (22), 2840-2861, 2015 | 185 | 2015 |
| Insulin action and signalling in fat and muscle from dexamethasone-treated rats J Burén, YC Lai, M Lundgren, JW Eriksson, J Jensen Archives of biochemistry and biophysics 474 (1), 91-101, 2008 | 159 | 2008 |
| AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B M Johanns, YC Lai, MF Hsu, R Jacobs, D Vertommen, J Van Sande, ... Nature communications 7 (1), 10856, 2016 | 147 | 2016 |
| Regulation of muscle glycogen synthase phosphorylation and kinetic properties by insulin, exercise, adrenaline and role in insulin resistance J Jensen, YC Lai Archives of physiology and biochemistry 115 (1), 13-21, 2009 | 133 | 2009 |
| AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner AP Seabright, NHF Fine, JP Barlow, SO Lord, I Musa, A Gray, JA Bryant, ... The FASEB Journal 34 (5), 6284, 2020 | 111 | 2020 |
| Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation KC Pao, M Stanley, C Han, YC Lai, P Murphy, K Balk, NT Wood, O Corti, ... Nature chemical biology 12 (5), 324-331, 2016 | 103 | 2016 |
| A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK … YC Lai, S Kviklyte, D Vertommen, L Lantier, M Foretz, B Viollet, S Hallén, ... Biochemical Journal 460 (3), 363-375, 2014 | 90 | 2014 |
| Kinetin riboside and its ProTides activate the Parkinson’s disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization L Osgerby, YC Lai, PJ Thornton, J Amalfitano, CS Le Duff, I Jabeen, ... Journal of medicinal chemistry 60 (8), 3518-3524, 2017 | 83 | 2017 |
| GSK-3β regulation in skeletal muscles by adrenaline and insulin: evidence that PKA and PKB regulate different pools of GSK-3 J Jensen, EO Brennesvik, YC Lai, PR Shepherd Cellular signalling 19 (1), 204-210, 2007 | 75 | 2007 |
| Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle Y Liu, YC Lai, EV Hill, D Tyteca, S Carpentier, A Ingvaldsen, ... Biochemical Journal 455 (2), 195-206, 2013 | 74 | 2013 |
| PDX1LOW MAFALOW β-cells contribute to islet function and insulin release D Nasteska, NHF Fine, FB Ashford, F Cuozzo, K Viloria, G Smith, A Dahir, ... Nature communications 12 (1), 674, 2021 | 66 | 2021 |
| Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle L Bultot, TE Jensen, YC Lai, ALB Madsen, C Collodet, S Kviklyte, M Deak, ... American Journal of Physiology-Endocrinology and Metabolism 311 (4), E706-E719, 2016 | 65 | 2016 |
| Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents YC Lai, E Zarrinpashneh, J Jensen Journal of applied physiology 108 (5), 1106-1115, 2010 | 63 | 2010 |
| A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle YC Lai, Y Liu, R Jacobs, MH Rider Biochemical Journal 447 (1), 137-147, 2012 | 60 | 2012 |
| Glycogen content and contraction regulate glycogen synthase phosphorylation and affinity for UDP-glucose in rat skeletal muscles YC Lai, JT Stuenæs, CH Kuo, J Jensen American Journal of Physiology-Endocrinology and Metabolism 293 (6), E1622-E1629, 2007 | 60 | 2007 |
| Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle Y Liu, D Vertommen, MH Rider, YC Lai Cellular signalling 25 (9), 1877-1886, 2013 | 59 | 2013 |
| Effects of adrenaline on whole-body glucose metabolism and insulin-mediated regulation of glycogen synthase and PKB phosphorylation in human skeletal muscle J Jensen, T Ruge, YC Lai, MK Svensson, JW Eriksson Metabolism 60 (2), 215-226, 2011 | 50 | 2011 |
| Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle C Plaideau, YC Lai, S Kviklyte, N Zanou, L Löfgren, H Andersén, ... Chemistry & biology 21 (11), 1497-1510, 2014 | 47 | 2014 |
