Matthias Sendler
Matthias Sendler
Junior research group leader, university medicine Greifswald
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Cited by
Cited by
Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer
A Aghdassi, M Sendler, A Guenther, J Mayerle, CO Behn, CD Heidecke, ...
Gut 61 (3), 439-448, 2012
Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice
M Sendler, A Dummer, FU Weiss, B Krüger, T Wartmann, ...
Gut 62 (3), 430-439, 2013
A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis
K Fjeld, FU Weiss, D Lasher, J Rosendahl, JM Chen, BB Johansson, ...
Nature genetics 47 (5), 518-522, 2015
Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis
J Maléth, A Balázs, P Pallagi, Z Balla, B Kui, M Katona, L Judák, I Németh, ...
Gastroenterology 148 (2), 427-439. e16, 2015
Genetics, cell biology, and pathophysiology of pancreatitis
J Mayerle, M Sendler, E Hegyi, G Beyer, MM Lerch, M Sahin-Tóth
Gastroenterology 156 (7), 1951-1968. e1, 2019
Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling
M Hohwieler, A Illing, PC Hermann, T Mayer, M Stockmann, L Perkhofer, ...
Gut 66 (3), 473-486, 2017
Cathepsin B-mediated activation of trypsinogen in endocytosing macrophages increases severity of pancreatitis in mice
M Sendler, FU Weiss, J Golchert, G Homuth, C van den Brandt, ...
Gastroenterology 154 (3), 704-718. e10, 2018
NLRP3 inflammasome regulates development of systemic inflammatory response and compensatory anti-inflammatory response syndromes in mice with acute pancreatitis
M Sendler, C van den Brandt, J Glaubitz, A Wilden, J Golchert, FU Weiss, ...
Gastroenterology 158 (1), 253-269. e14, 2020
Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice
T Wartmann, J Mayerle, T Kähne, M Sahin–Tóth, M Ruthenbürger, ...
Gastroenterology 138 (2), 726-737, 2010
Immune cell and stromal signature associated with progression-free survival of patients with resected pancreatic ductal adenocarcinoma
UM Mahajan, E Langhoff, E Goni, E Costello, W Greenhalf, C Halloran, ...
Gastroenterology 155 (5), 1625-1639. e2, 2018
Animal models for investigating chronic pancreatitis
AA Aghdassi, J Mayerle, S Christochowitz, FU Weiss, M Sendler, ...
Fibrogenesis & tissue repair 4, 1-16, 2011
Chronic stress increases experimental pancreatic cancer growth, reduces survival and can be antagonised by beta-adrenergic receptor blockade
LI Partecke, S Speerforck, A Käding, F Seubert, S Kühn, E Lorenz, ...
Pancreatology 16 (3), 423-433, 2016
Lysosome-associated membrane proteins (LAMP) maintain pancreatic acinar cell homeostasis: LAMP-2–deficient mice develop pancreatitis
OA Mareninova, M Sendler, SR Malla, I Yakubov, SW French, ...
Cellular and molecular gastroenterology and hepatology 1 (6), 678-694, 2015
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
A Mahajan, X Sim, HJ Ng, A Manning, MA Rivas, HM Highland, AE Locke, ...
PLoS genetics 11 (1), e1004876, 2015
Complement component 5 mediates development of fibrosis, via activation of stellate cells, in 2 mouse models of chronic pancreatitis
M Sendler, G Beyer, UM Mahajan, V Kauschke, S Maertin, C Schurmann, ...
Gastroenterology 149 (3), 765-776. e10, 2015
Cathepsin B activity initiates apoptosis via digestive protease activation in pancreatic acinar cells and experimental pancreatitis
M Sendler, S Maertin, D John, M Persike, FU Weiss, B Krüger, ...
Journal of Biological Chemistry 291 (28), 14717-14731, 2016
Impaired exocrine pancreatic function associates with changes in intestinal microbiota composition and diversity
F Frost, T Kacprowski, M Rühlemann, R Bülow, JP Kühn, A Franke, ...
Gastroenterology 156 (4), 1010-1015, 2019
Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer
UM Mahajan, S Teller, M Sendler, R Palankar, C van den Brandt, ...
Gut 65 (11), 1838-1849, 2016
A syngeneic orthotopic murine model of pancreatic adenocarcinoma in the C57/BL6 mouse using the Panc02 and 6606PDA cell lines
LI Partecke, M Sendler, A Kaeding, FU Weiss, J Mayerle, A Dummer, ...
European Surgical Research 47 (2), 98-107, 2011
Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function
F Frost, T Kacprowski, M Rühlemann, M Pietzner, C Bang, A Franke, ...
Gut 70 (3), 522-530, 2021
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