David Hafler
David Hafler
Professor of Neurology and Immunobiology, Yale University
Verified email at - Homepage
Cited by
Cited by
Integrative analysis of 111 reference human epigenomes
A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ...
Nature 518 (7539), 317-330, 2015
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Nature 476 (7359), 214-219, 2011
FOXP3+ regulatory T cells in the human immune system
S Sakaguchi, M Miyara, CM Costantino, DA Hafler
Nature Reviews Immunology 10 (7), 490-500, 2010
CD4+ CD25high regulatory cells in human peripheral blood
C Baecher-Allan, JA Brown, GJ Freeman, DA Hafler
The Journal of Immunology 167 (3), 1245-1253, 2001
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
Y Chen, VK Kuchroo, J Inobe, DA Hafler, HL Weiner
Science 265 (5176), 1237-1240, 1994
Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis
V Viglietta, C Baecher-Allan, HL Weiner, DA Hafler
The Journal of experimental medicine 199 (7), 971-979, 2004
Risk alleles for multiple sclerosis identified by a genomewide study
D Hafler
New England Journal of Medicine 357, 851, 2007
Genetic and epigenetic fine mapping of causal autoimmune disease variants
KKH Farh, A Marson, J Zhu, M Kleinewietfeld, WJ Housley, S Beik, ...
Nature 518 (7539), 337-343, 2015
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
M Kleinewietfeld, A Manzel, J Titze, H Kvakan, N Yosef, RA Linker, ...
Nature 496 (7446), 518-522, 2013
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
International IBD Genetics Consortium (IIBDGC), C Agliardi, L Alfredsson, ...
Nature genetics 45 (11), 1353-1360, 2013
IL-21 and TGF-β are required for differentiation of human TH17 cells
L Yang, DE Anderson, C Baecher-Allan, WD Hastings, E Bettelli, M Oukka, ...
Nature 454 (7202), 350-352, 2008
Induction and molecular signature of pathogenic TH17 cells
Y Lee, A Awasthi, N Yosef, FJ Quintana, S Xiao, A Peters, C Wu, ...
Nature immunology 13 (10), 991-999, 2012
Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens.
HL Weiner, A Friedman, A Miller, SJ Khoury, A Al-Sabbagh, L Santos, ...
Annual review of immunology 12, 809-837, 1994
T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis
K Ota, M Matsui, EL Milford, GA Mackin, HL Weiner, DA Hafler
Nature 346 (6280), 183-187, 1990
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
PL De Jager, X Jia, J Wang, PIW De Bakker, L Ottoboni, NT Aggarwal, ...
Nature genetics 41 (7), 776-782, 2009
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
PIW De Bakker, G McVean, PC Sabeti, MM Miretti, T Green, J Marchini, ...
Nature genetics 38 (10), 1166-1172, 2006
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
International Multiple Sclerosis Genetics Consortium*†, ANZgene, ...
Science 365 (6460), eaav7188, 2019
Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses
N Joller, E Lozano, PR Burkett, B Patel, S Xiao, C Zhu, J Xia, TG Tan, ...
Immunity 40 (4), 569-581, 2014
Effects of oral administration of type II collagen on rheumatoid arthritis
DE Trentham, RA Dynesius-Trentham, EJ Orav, D Combitchi, C Lorenzo, ...
Science 261 (5129), 1727-1730, 1993
Erratum: Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes
SB Wilson, SC Kent, KT Patton, T Orban, RA Jackson, M Exley, S Porcelli, ...
Nature 399 (6731), 84-84, 1999
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