Crystal shape engineering MA Lovette, AR Browning, DW Griffin, JP Sizemore, RC Snyder, ... Industrial & engineering chemistry research 47 (24), 9812-9833, 2008 | 391 | 2008 |
Needle-shaped crystals: causality and solvent selection guidance based on periodic bond chains MA Lovette, MF Doherty Crystal growth & design 13 (8), 3341-3352, 2013 | 109 | 2013 |
Predictive modeling of supersaturation-dependent crystal shapes MA Lovette, MF Doherty Crystal growth & design 12 (2), 656-669, 2012 | 99 | 2012 |
Perspectives on the current state, challenges, and opportunities in pharmaceutical crystallization process development A Cote, D Erdemir, KP Girard, DA Green, MA Lovette, E Sirota, NK Nere Crystal Growth & Design 20 (12), 7568-7581, 2020 | 80 | 2020 |
Crystal shape modification through cycles of dissolution and growth: Attainable regions and experimental validation MA Lovette, M Muratore, MF Doherty AIChE Journal 58 (5), 1465-1474, 2011 | 68 | 2011 |
Multisite models to determine the distribution of kink sites adjacent to low-energy edges MA Lovette, MF Doherty Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 85 (2 …, 2012 | 32 | 2012 |
Kink rate model for the general case of organic molecular crystals SH Kim, P Dandekar, MA Lovette, MF Doherty Crystal growth & design 14 (5), 2460-2467, 2014 | 28 | 2014 |
Continuous process improvement in the manufacture of Carfilzomib, part 2: an improved process for synthesis of the Epoxyketone warhead MG Beaver, X Shi, J Riedel, P Patel, A Zeng, MT Corbett, JA Robinson, ... Organic Process Research & Development 24 (4), 490-499, 2020 | 25 | 2020 |
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor L Zhang, DJ Griffin, MG Beaver, LE Blue, CJ Borths, DB Brown, S Caille, ... Organic Process Research & Development 26 (11), 3115-3125, 2022 | 20 | 2022 |
Reinterpreting edge energies calculated from crystal growth experiments MA Lovette, MF Doherty Journal of crystal growth 327 (1), 117-126, 2011 | 19 | 2011 |
Axial chirality in the sotorasib drug substance, Part 1: Development of a classical resolution to prepare an atropisomerically pure sotorasib intermediate AT Parsons, S Caille, MA Caporini, DJ Griffin, MA Lovette, W Powazinik IV, ... Organic Process Research & Development 26 (9), 2629-2635, 2022 | 17 | 2022 |
Cross-pharma collaboration for the development of a simulation tool for the model-based digital design of pharmaceutical crystallization processes (CrySiV) B Szilagyi, WL Wu, A Eren, J Mackey, S Kshirsagar, E Szilagyi, ... Crystal Growth & Design 21 (11), 6448-6464, 2021 | 15 | 2021 |
Implementing continuous manufacturing for the final methylation step in the AMG 397 process to deliver key quality attributes JK Tom, MM Achmatowicz, MG Beaver, J Colyer, A Ericson, TL Hwang, ... Organic Process Research & Development 25 (3), 486-499, 2021 | 14 | 2021 |
Evaluation of predictive solubility models in pharmaceutical process development─ an enabling technologies consortium collaboration MA Lovette, J Albrecht, RS Ananthula, F Ricci, R Sangodkar, MS Shah, ... Crystal Growth & Design 22 (9), 5239-5263, 2022 | 8 | 2022 |
Chiral control of enantiomers through crystallization: Moving from ternary phase diagrams to design spaces MA Lovette AIChE Journal 64 (9), 3323-3331, 2018 | 6 | 2018 |
A Continuous Process for Manufacturing Apremilast. Part I: Process Development and Intensification by Utilizing Flow Chemistry Principles HW Hsieh, CM Cohen, DJ Griffin, P Ananthoji, NH Avci, DB Brown, ... Organic Process Research & Development 28 (5), 1369-1384, 2024 | 5 | 2024 |
Solubility Model to Guide Solvent Selection in Synthetic Process Development MA Lovette Crystal Growth & Design 22 (7), 4404-4420, 2022 | 4 | 2022 |
Introduction To Chiral Crystallization In Pharmaceutical Development And Manufacturing JE Tabora, S Brueggemeier, J Sweeney, M Lovette Chemical Engineering in the Pharmaceutical Industry: Active Pharmaceutical …, 2019 | 4 | 2019 |
Prediction and Modification of Crystal Shapes MA Lovette Dissertation Abstracts International 73 (03), 2011 | 2 | 2011 |
Ring Closing Synthesis of Macrocyclic MCL-1 Inhibitor Intermediates AG Smith, JS Tedrow, STP Gabrielle, OR Thiel, L Huang, PC Roosen, ... US Patent App. 17/922,619, 2023 | | 2023 |