Lipid metabolism reprogramming and its potential targets in cancer C Cheng, F Geng, X Cheng, D Guo Cancer communications 38, 1-14, 2018 | 545 | 2018 |
Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells Q Shi, L Qin, W Wei, F Geng, R Fan, Y Shik Shin, D Guo, L Hood, ... Proceedings of the National Academy of Sciences 109 (2), 419-424, 2012 | 354 | 2012 |
Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1–mediated lipogenesis F Geng, X Cheng, X Wu, JY Yoo, C Cheng, JY Guo, X Mo, P Ru, B Hurwitz, ... Clinical Cancer Research 22 (21), 5337-5348, 2016 | 256 | 2016 |
Glucose-mediated N-glycosylation of SCAP is essential for SREBP-1 activation and tumor growth C Cheng, P Ru, F Geng, J Liu, JY Yoo, X Wu, X Cheng, V Euthine, P Hu, ... Cancer cell 28 (5), 569-581, 2015 | 238 | 2015 |
Targeting DGAT1 ameliorates glioblastoma by increasing fat catabolism and oxidative stress X Cheng, F Geng, M Pan, X Wu, Y Zhong, C Wang, Z Tian, C Cheng, ... Cell metabolism 32 (2), 229-242. e8, 2020 | 180 | 2020 |
Inhibition of bladder cancer development by allyl isothiocyanate A Bhattacharya, L Tang, Y Li, F Geng, JD Paonessa, SC Chen, ... Carcinogenesis 31 (2), 281-286, 2010 | 96 | 2010 |
Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylation F Geng, L Tang, Y Li, L Yang, KS Choi, AL Kazim, Y Zhang Journal of Biological Chemistry 286 (37), 32259-32267, 2011 | 93 | 2011 |
Feedback loop regulation of SCAP/SREBP-1 by miR-29 modulates EGFR signaling-driven glioblastoma growth P Ru, P Hu, F Geng, X Mo, C Cheng, JY Yoo, X Cheng, X Wu, JY Guo, ... Cell reports 16 (6), 1527-1535, 2016 | 84 | 2016 |
Lipid droplets, potential biomarker and metabolic target in glioblastoma F Geng, D Guo Internal medicine review (Washington, DC: Online) 3 (5), 2017 | 76 | 2017 |
Lipid droplets maintain energy homeostasis and glioblastoma growth via autophagic release of stored fatty acids X Wu, F Geng, X Cheng, Q Guo, Y Zhong, TF Cloughesy, WH Yong, ... Iscience 23 (10), 2020 | 65 | 2020 |
The principal urinary metabolite of allyl isothiocyanate, N -acetyl- S -( N -allylthiocarbamoyl)cysteine, inhibits the growth … A Bhattacharya, Y Li, F Geng, R Munday, Y Zhang Carcinogenesis 33 (2), 394-398, 2012 | 42 | 2012 |
Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth C Cheng, F Geng, Z Li, Y Zhong, H Wang, X Cheng, Y Zhao, X Mo, ... Nature metabolism 4 (5), 575-588, 2022 | 36 | 2022 |
Lipid metabolism in glioblastoma: from de novo synthesis to storage Y Kou, F Geng, D Guo Biomedicines 10 (8), 1943, 2022 | 18 | 2022 |
Analysis of SCAP N-glycosylation and Trafficking in Human Cells C Cheng, JY Guo, F Geng, X Wu, X Cheng, Q Li, D Guo JoVE (Journal of Visualized Experiments), e54709, 2016 | 16 | 2016 |
DGAT1 protects tumor from lipotoxicity, emerging as a promising metabolic target for cancer therapy X Cheng, F Geng, D Guo Molecular & Cellular Oncology 7 (6), 1805257, 2020 | 15 | 2020 |
Calcineurin B stimulates cytokine production through a CD14‐independent Toll‐like receptor 4 pathway W Wu, Q Chen, F Geng, L Tong, R Yang, J Yang, H Zhang, Z Jia, Q Wei Immunology and cell biology 94 (3), 285-292, 2016 | 8 | 2016 |
Method for delivery and use of isothiocyanates for prophylaxis and/or therapy of bladder cancer Y Zhang, A Bhattacharya, L Tang, Y Li, JD Paonessa, F Geng, Y Ding US Patent 9,486,434, 2016 | 6 | 2016 |
SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells F Geng, Y Zhong, H Su, E Lefai, S Magaki, TF Cloughesy, WH Yong, ... Cell reports 42 (7), 2023 | 3 | 2023 |
Interplay of lipid droplets and autophagy regulates glioblastoma survival D Guo, F Geng, R Aggarwal, J Liu, JY Yoo, Q Guo, JY Guo, B Hurwitz, ... Neuro-oncology 16 (suppl_3), iii9-iii9, 2014 | 2 | 2014 |
Lipid droplets promote glioblastoma cell growth through maintaining cholesterol homeostasis mediated by autophagy F Geng, X Cheng, C Cheng, A Chakravarti, D Guo Cancer Research 78 (13_Supplement), 2419-2419, 2018 | 1 | 2018 |