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Feng Geng
Feng Geng
Professor, Harbin Medical University Cancer Hospital
Adresă de e-mail confirmată pe hrbmu.edu.cn
Titlu
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Lipid metabolism reprogramming and its potential targets in cancer
C Cheng, F Geng, X Cheng, D Guo
Cancer communications 38, 1-14, 2018
5452018
Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells
Q Shi, L Qin, W Wei, F Geng, R Fan, Y Shik Shin, D Guo, L Hood, ...
Proceedings of the National Academy of Sciences 109 (2), 419-424, 2012
3542012
Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1–mediated lipogenesis
F Geng, X Cheng, X Wu, JY Yoo, C Cheng, JY Guo, X Mo, P Ru, B Hurwitz, ...
Clinical Cancer Research 22 (21), 5337-5348, 2016
2562016
Glucose-mediated N-glycosylation of SCAP is essential for SREBP-1 activation and tumor growth
C Cheng, P Ru, F Geng, J Liu, JY Yoo, X Wu, X Cheng, V Euthine, P Hu, ...
Cancer cell 28 (5), 569-581, 2015
2382015
Targeting DGAT1 ameliorates glioblastoma by increasing fat catabolism and oxidative stress
X Cheng, F Geng, M Pan, X Wu, Y Zhong, C Wang, Z Tian, C Cheng, ...
Cell metabolism 32 (2), 229-242. e8, 2020
1802020
Inhibition of bladder cancer development by allyl isothiocyanate
A Bhattacharya, L Tang, Y Li, F Geng, JD Paonessa, SC Chen, ...
Carcinogenesis 31 (2), 281-286, 2010
962010
Allyl isothiocyanate arrests cancer cells in mitosis, and mitotic arrest in turn leads to apoptosis via Bcl-2 protein phosphorylation
F Geng, L Tang, Y Li, L Yang, KS Choi, AL Kazim, Y Zhang
Journal of Biological Chemistry 286 (37), 32259-32267, 2011
932011
Feedback loop regulation of SCAP/SREBP-1 by miR-29 modulates EGFR signaling-driven glioblastoma growth
P Ru, P Hu, F Geng, X Mo, C Cheng, JY Yoo, X Cheng, X Wu, JY Guo, ...
Cell reports 16 (6), 1527-1535, 2016
842016
Lipid droplets, potential biomarker and metabolic target in glioblastoma
F Geng, D Guo
Internal medicine review (Washington, DC: Online) 3 (5), 2017
762017
Lipid droplets maintain energy homeostasis and glioblastoma growth via autophagic release of stored fatty acids
X Wu, F Geng, X Cheng, Q Guo, Y Zhong, TF Cloughesy, WH Yong, ...
Iscience 23 (10), 2020
652020
The principal urinary metabolite of allyl isothiocyanate, N -acetyl- S -( N -allylthiocarbamoyl)cysteine, inhibits the growth …
A Bhattacharya, Y Li, F Geng, R Munday, Y Zhang
Carcinogenesis 33 (2), 394-398, 2012
422012
Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth
C Cheng, F Geng, Z Li, Y Zhong, H Wang, X Cheng, Y Zhao, X Mo, ...
Nature metabolism 4 (5), 575-588, 2022
362022
Lipid metabolism in glioblastoma: from de novo synthesis to storage
Y Kou, F Geng, D Guo
Biomedicines 10 (8), 1943, 2022
182022
Analysis of SCAP N-glycosylation and Trafficking in Human Cells
C Cheng, JY Guo, F Geng, X Wu, X Cheng, Q Li, D Guo
JoVE (Journal of Visualized Experiments), e54709, 2016
162016
DGAT1 protects tumor from lipotoxicity, emerging as a promising metabolic target for cancer therapy
X Cheng, F Geng, D Guo
Molecular & Cellular Oncology 7 (6), 1805257, 2020
152020
Calcineurin B stimulates cytokine production through a CD14‐independent Toll‐like receptor 4 pathway
W Wu, Q Chen, F Geng, L Tong, R Yang, J Yang, H Zhang, Z Jia, Q Wei
Immunology and cell biology 94 (3), 285-292, 2016
82016
Method for delivery and use of isothiocyanates for prophylaxis and/or therapy of bladder cancer
Y Zhang, A Bhattacharya, L Tang, Y Li, JD Paonessa, F Geng, Y Ding
US Patent 9,486,434, 2016
62016
SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells
F Geng, Y Zhong, H Su, E Lefai, S Magaki, TF Cloughesy, WH Yong, ...
Cell reports 42 (7), 2023
32023
Interplay of lipid droplets and autophagy regulates glioblastoma survival
D Guo, F Geng, R Aggarwal, J Liu, JY Yoo, Q Guo, JY Guo, B Hurwitz, ...
Neuro-oncology 16 (suppl_3), iii9-iii9, 2014
22014
Lipid droplets promote glioblastoma cell growth through maintaining cholesterol homeostasis mediated by autophagy
F Geng, X Cheng, C Cheng, A Chakravarti, D Guo
Cancer Research 78 (13_Supplement), 2419-2419, 2018
12018
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