Pathways and progress in improving drug delivery through the intestinal mucosa and blood–brain barriers M Laksitorini, VD Prasasty, PK Kiptoo, TJ Siahaan Therapeutic delivery 5 (10), 1143-1163, 2014 | 129 | 2014 |
Vaccine-like controlled-release delivery of an immunomodulating peptide to treat experimental autoimmune encephalomyelitis B Büyüktimkin, Q Wang, P Kiptoo, JM Stewart, C Berkland, TJ Siahaan Molecular pharmaceutics 9 (4), 979-985, 2012 | 89 | 2012 |
Modulation of blood–brain barrier permeability in mice using synthetic E-cadherin peptide NH On, P Kiptoo, TJ Siahaan, DW Miller Molecular pharmaceutics 11 (3), 974-981, 2014 | 58 | 2014 |
Enhancement of drug absorption through the blood− brain barrier and inhibition of intercellular tight junction resealing by E-cadherin peptides P Kiptoo, E Sinaga, AM Calcagno, H Zhao, N Kobayashi, USF Tambunan, ... Molecular pharmaceutics 8 (1), 239-249, 2011 | 58 | 2011 |
Enhancement of transdermal delivery of 6-β-naltrexol via a codrug linked to hydroxybupropion PK Kiptoo, MO Hamad, PA Crooks, AL Stinchcomb Journal of controlled release 113 (2), 137-145, 2006 | 58 | 2006 |
Synthesis and hydrolytic behavior of two novel tripartate codrugs of naltrexone and 6β-naltrexol with hydroxybupropion as potential alcohol abuse and smoking cessation agents MO Hamad, PK Kiptoo, AL Stinchcomb, PA Crooks Bioorganic & medicinal chemistry 14 (20), 7051-7061, 2006 | 53 | 2006 |
Modulation of intercellular junctions by cyclic-ADT peptides as a method to reversibly increase blood–brain barrier permeability MD Laksitorini, PK Kiptoo, NH On, JA Thliveris, DW Miller, TJ Siahaan Journal of pharmaceutical sciences 104 (3), 1065-1075, 2015 | 48 | 2015 |
Transdermal delivery of naltrexone and its active metabolite 6-β-naltrexol in human skin in vitro and guinea pigs in vivo KS Paudel, BN Nalluri, DC Hammell, S Valiveti, P Kiptoo, MO Hamad, ... Journal of pharmaceutical sciences 94 (9), 1965-1975, 2005 | 42 | 2005 |
Comparison of linear and cyclic His-Ala-Val peptides in modulating the blood-brain barrier permeability: impact on delivery of molecules to the brain A Alaofi, N On, P Kiptoo, TD Williams, DW Miller, TJ Siahaan Journal of pharmaceutical sciences 105 (2), 797-807, 2016 | 41 | 2016 |
Prophylactic and therapeutic suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor N Kobayashi, P Kiptoo, H Kobayashi, R Ridwan, S Brocke, TJ Siahaan Clinical immunology 129 (1), 69-79, 2008 | 37 | 2008 |
Antigen‐specific blocking of CD4‐specific immunological synapse formation using BPI and current therapies for autoimmune diseases P Manikwar, P Kiptoo, AH Badawi, B Büyüktimkin, TJ Siahaan Medicinal research reviews 32 (4), 727-764, 2012 | 35 | 2012 |
Antigen-specific suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor: structure optimization and pharmacokinetics R Ridwan, P Kiptoo, N Kobayashi, S Weir, M Hughes, T Williams, ... Journal of Pharmacology and Experimental Therapeutics 332 (3), 1136-1145, 2010 | 34 | 2010 |
Transdermal permeation of WIN 55,212-2 and CP 55,940 in human skin in vitro S Valiveti, PK Kiptoo, DC Hammell, AL Stinchcomb International journal of pharmaceutics 278 (1), 173-180, 2004 | 34 | 2004 |
Transdermal delivery of bupropion and its active metabolite, hydroxybupropion: a prodrug strategy as an alternative approach PK Kiptoo, KS Paudel, DC Hammell, RR Pinninti, J Chen, PA Crooks, ... Journal of pharmaceutical sciences 98 (2), 583-594, 2009 | 33 | 2009 |
In vivo evaluation of a transdermal codrug of 6-β-naltrexol linked to hydroxybupropion in hairless guinea pigs PK Kiptoo, KS Paudel, DC Hammell, MO Hamad, PA Crooks, ... European journal of pharmaceutical sciences 33 (4-5), 371-379, 2008 | 33 | 2008 |
Suppression of EAE and prevention of blood–brain barrier breakdown after vaccination with novel bifunctional peptide inhibitor AH Badawi, P Kiptoo, WT Wang, IY Choi, P Lee, CM Vines, TJ Siahaan Neuropharmacology 62 (4), 1874-1881, 2012 | 32 | 2012 |
Improving brain delivery of biomolecules via BBB modulation in mouse and rat: detection using MRI, NIRF, and mass spectrometry KR Ulapane, N On, P Kiptoo, TD Williams, DW Miller, TJ Siahaan Nanotheranostics 1 (2), 217, 2017 | 30 | 2017 |
Immune response to controlled release of immunomodulating peptides in a murine experimental autoimmune encephalomyelitis (EAE) model H Zhao, P Kiptoo, TD Williams, TJ Siahaan, EM Topp Journal of controlled release 141 (2), 145-152, 2010 | 29 | 2010 |
Noninvasive brain delivery and efficacy of BDNF to stimulate neuroregeneration and suppression of disease relapse in EAE mice BM Kopec, P Kiptoo, L Zhao, E Rosa-Molinar, TJ Siahaan Molecular pharmaceutics 17 (2), 404-416, 2019 | 25 | 2019 |
Brain delivery of drug and MRI contrast agent: detection and quantitative determination of brain deposition of CPT-glu using LC–MS/MS and Gd-DTPA using magnetic resonance imaging K Tabanor, P Lee, P Kiptoo, IY Choi, EB Sherry, CS Eagle, TD Williams, ... Molecular pharmaceutics 13 (2), 379-390, 2016 | 21 | 2016 |