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Paul Kiptoo
Paul Kiptoo
University of Kansas, University of Kentucky
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Year
Pathways and progress in improving drug delivery through the intestinal mucosa and blood–brain barriers
M Laksitorini, VD Prasasty, PK Kiptoo, TJ Siahaan
Therapeutic delivery 5 (10), 1143-1163, 2014
1292014
Vaccine-like controlled-release delivery of an immunomodulating peptide to treat experimental autoimmune encephalomyelitis
B Büyüktimkin, Q Wang, P Kiptoo, JM Stewart, C Berkland, TJ Siahaan
Molecular pharmaceutics 9 (4), 979-985, 2012
892012
Modulation of blood–brain barrier permeability in mice using synthetic E-cadherin peptide
NH On, P Kiptoo, TJ Siahaan, DW Miller
Molecular pharmaceutics 11 (3), 974-981, 2014
582014
Enhancement of drug absorption through the blood− brain barrier and inhibition of intercellular tight junction resealing by E-cadherin peptides
P Kiptoo, E Sinaga, AM Calcagno, H Zhao, N Kobayashi, USF Tambunan, ...
Molecular pharmaceutics 8 (1), 239-249, 2011
582011
Enhancement of transdermal delivery of 6-β-naltrexol via a codrug linked to hydroxybupropion
PK Kiptoo, MO Hamad, PA Crooks, AL Stinchcomb
Journal of controlled release 113 (2), 137-145, 2006
582006
Synthesis and hydrolytic behavior of two novel tripartate codrugs of naltrexone and 6β-naltrexol with hydroxybupropion as potential alcohol abuse and smoking cessation agents
MO Hamad, PK Kiptoo, AL Stinchcomb, PA Crooks
Bioorganic & medicinal chemistry 14 (20), 7051-7061, 2006
532006
Modulation of intercellular junctions by cyclic-ADT peptides as a method to reversibly increase blood–brain barrier permeability
MD Laksitorini, PK Kiptoo, NH On, JA Thliveris, DW Miller, TJ Siahaan
Journal of pharmaceutical sciences 104 (3), 1065-1075, 2015
482015
Transdermal delivery of naltrexone and its active metabolite 6-β-naltrexol in human skin in vitro and guinea pigs in vivo
KS Paudel, BN Nalluri, DC Hammell, S Valiveti, P Kiptoo, MO Hamad, ...
Journal of pharmaceutical sciences 94 (9), 1965-1975, 2005
422005
Comparison of linear and cyclic His-Ala-Val peptides in modulating the blood-brain barrier permeability: impact on delivery of molecules to the brain
A Alaofi, N On, P Kiptoo, TD Williams, DW Miller, TJ Siahaan
Journal of pharmaceutical sciences 105 (2), 797-807, 2016
412016
Prophylactic and therapeutic suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor
N Kobayashi, P Kiptoo, H Kobayashi, R Ridwan, S Brocke, TJ Siahaan
Clinical immunology 129 (1), 69-79, 2008
372008
Antigen‐specific blocking of CD4‐specific immunological synapse formation using BPI and current therapies for autoimmune diseases
P Manikwar, P Kiptoo, AH Badawi, B BŁyŁktimkin, TJ Siahaan
Medicinal research reviews 32 (4), 727-764, 2012
352012
Antigen-specific suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor: structure optimization and pharmacokinetics
R Ridwan, P Kiptoo, N Kobayashi, S Weir, M Hughes, T Williams, ...
Journal of Pharmacology and Experimental Therapeutics 332 (3), 1136-1145, 2010
342010
Transdermal permeation of WIN 55,212-2 and CP 55,940 in human skin in vitro
S Valiveti, PK Kiptoo, DC Hammell, AL Stinchcomb
International journal of pharmaceutics 278 (1), 173-180, 2004
342004
Transdermal delivery of bupropion and its active metabolite, hydroxybupropion: a prodrug strategy as an alternative approach
PK Kiptoo, KS Paudel, DC Hammell, RR Pinninti, J Chen, PA Crooks, ...
Journal of pharmaceutical sciences 98 (2), 583-594, 2009
332009
In vivo evaluation of a transdermal codrug of 6-β-naltrexol linked to hydroxybupropion in hairless guinea pigs
PK Kiptoo, KS Paudel, DC Hammell, MO Hamad, PA Crooks, ...
European journal of pharmaceutical sciences 33 (4-5), 371-379, 2008
332008
Suppression of EAE and prevention of blood–brain barrier breakdown after vaccination with novel bifunctional peptide inhibitor
AH Badawi, P Kiptoo, WT Wang, IY Choi, P Lee, CM Vines, TJ Siahaan
Neuropharmacology 62 (4), 1874-1881, 2012
322012
Improving brain delivery of biomolecules via BBB modulation in mouse and rat: detection using MRI, NIRF, and mass spectrometry
KR Ulapane, N On, P Kiptoo, TD Williams, DW Miller, TJ Siahaan
Nanotheranostics 1 (2), 217, 2017
302017
Immune response to controlled release of immunomodulating peptides in a murine experimental autoimmune encephalomyelitis (EAE) model
H Zhao, P Kiptoo, TD Williams, TJ Siahaan, EM Topp
Journal of controlled release 141 (2), 145-152, 2010
292010
Noninvasive brain delivery and efficacy of BDNF to stimulate neuroregeneration and suppression of disease relapse in EAE mice
BM Kopec, P Kiptoo, L Zhao, E Rosa-Molinar, TJ Siahaan
Molecular pharmaceutics 17 (2), 404-416, 2019
252019
Brain delivery of drug and MRI contrast agent: detection and quantitative determination of brain deposition of CPT-glu using LC–MS/MS and Gd-DTPA using magnetic resonance imaging
K Tabanor, P Lee, P Kiptoo, IY Choi, EB Sherry, CS Eagle, TD Williams, ...
Molecular pharmaceutics 13 (2), 379-390, 2016
212016
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