Karl Mechtler
Karl Mechtler
Head of Protein Chemistry Facility
Verified email at - Homepage
Cited by
Cited by
Regulation of chromatin structure by site-specific histone H3 methyltransferases
S Rea, F Eisenhaber, D O'Carroll, BD Strahl, ZW Sun, M Schmid, ...
Nature 406 (6796), 593-599, 2000
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
M Lachner, D O'Carroll, S Rea, K Mechtler, T Jenuwein
Nature 410 (6824), 116-120, 2001
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
AHFM Peters, D O'Carroll, H Scherthan, K Mechtler, S Sauer, C Schöfer, ...
Cell 107 (3), 323-337, 2001
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin
AHFM Peters, S Kubicek, K Mechtler, RJ O'Sullivan, AAHA Derijck, ...
Molecular cell 12 (6), 1577-1589, 2003
The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.
C Plank, B Oberhauser, K Mechtler, C Koch, E Wagner
Journal of Biological Chemistry 269 (17), 12918-12924, 1994
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase
S Kubicek, RJ O'Sullivan, EM August, ER Hickey, Q Zhang, ML Teodoro, ...
Molecular cell 25 (3), 473-481, 2007
Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery
C Plank, K Mechtler, FC Szoka Jr, E Wagner
Human gene therapy 7 (12), 1437-1446, 1996
The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
M Ogris, P Steinlein, M Kursa, K Mechtler, R Kircheis, E Wagner
Gene therapy 5 (10), 1425-1433, 1998
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.
E Wagner, K Zatloukal, M Cotten, H Kirlappos, K Mechtler, DT Curiel, ...
Proceedings of the national academy of sciences 89 (13), 6099-6103, 1992
Universal and confident phosphorylation site localization using phosphoRS
T Taus, T Köcher, P Pichler, C Paschke, A Schmidt, C Henrich, ...
Journal of proteome research 10 (12), 5354-5362, 2011
The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl
J Betschinger, K Mechtler, JA Knoblich
nature 422 (6929), 326-330, 2003
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals
I Poser, M Sarov, JRA Hutchins, JK Hériché, Y Toyoda, A Pozniakovsky, ...
Nature methods 5 (5), 409-415, 2008
Wapl controls the dynamic association of cohesin with chromatin
S Kueng, B Hegemann, BH Peters, JJ Lipp, A Schleiffer, K Mechtler, ...
Cell 127 (5), 955-967, 2006
Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells
J Betschinger, K Mechtler, JA Knoblich
Cell 124 (6), 1241-1253, 2006
Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2
S Hauf, E Roitinger, B Koch, CM Dittrich, K Mechtler, JM Peters
PLoS biology 3 (3), e69, 2005
Systematic analysis of human protein complexes identifies chromosome segregation proteins
JRA Hutchins, Y Toyoda, B Hegemann, I Poser, JK Hériché, MM Sykora, ...
Science 328 (5978), 593-599, 2010
Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin …
M Cotten, F Längle-Rouault, H Kirlappos, E Wagner, K Mechtler, M Zenke, ...
Proceedings of the National Academy of Sciences 87 (11), 4033-4037, 1990
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I
CG Riedel, VL Katis, Y Katou, S Mori, T Itoh, W Helmhart, M Gálová, ...
Nature 441 (7089), 53-61, 2006
Mitotic regulation of the human anaphase-promoting complex by phosphorylation
C Kraft, F Herzog, C Gieffers, K Mechtler, A Hagting, J Pines, JM Peters
The EMBO journal 22 (24), 6598-6609, 2003
Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast
G Alexandru, F Uhlmann, K Mechtler, MA Poupart, K Nasmyth
Cell 105 (4), 459-472, 2001
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