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Ari Melnick
Ari Melnick
Professor of Medicine, Weill Cornell Medicine
Adresă de e-mail confirmată pe med.cornell.edu - Pagina de pornire
Titlu
Citat de
Citat de
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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
ME Figueroa, O Abdel-Wahab, C Lu, PS Ward, J Patel, A Shih, Y Li, ...
Cancer cell 18 (6), 553-567, 2010
30162010
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
JP Patel, M Gönen, ME Figueroa, H Fernandez, Z Sun, J Racevskis, ...
New England Journal of Medicine 366 (12), 1079-1089, 2012
23142012
IDH mutation impairs histone demethylation and results in a block to cell differentiation
C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ...
Nature 483 (7390), 474-478, 2012
21212012
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles
A Akalin, M Kormaksson, S Li, FE Garrett-Bakelman, ME Figueroa, ...
Genome biology 13, 1-9, 2012
16942012
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
K Moran-Crusio, L Reavie, A Shih, O Abdel-Wahab, D Ndiaye-Lobry, ...
Cancer cell 20 (1), 11-24, 2011
14202011
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
JM Polo, S Liu, ME Figueroa, W Kulalert, S Eminli, KY Tan, E Apostolou, ...
Nature biotechnology 28 (8), 848-855, 2010
14022010
Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia
A Melnick, JD Licht
Blood, The Journal of the American Society of Hematology 93 (10), 3167-3215, 1999
13781999
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
LP Vu, BF Pickering, Y Cheng, S Zaccara, D Nguyen, G Minuesa, T Chou, ...
Nature medicine 23 (11), 1369-1376, 2017
10122017
A molecular roadmap of reprogramming somatic cells into iPS cells
JM Polo, E Anderssen, RM Walsh, BA Schwarz, CM Nefzger, SM Lim, ...
Cell 151 (7), 1617-1632, 2012
9792012
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia
ME Figueroa, S Lugthart, Y Li, C Erpelinck-Verschueren, X Deng, ...
Cancer cell 17 (1), 13-27, 2010
9602010
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation
W Béguelin, R Popovic, M Teater, Y Jiang, KL Bunting, M Rosen, H Shen, ...
Cancer cell 23 (5), 677-692, 2013
8992013
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
L Busque, JP Patel, ME Figueroa, A Vasanthakumar, S Provost, ...
Nature genetics 44 (11), 1179-1181, 2012
8592012
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
FE Garrett-Bakelman, M Darshi, SJ Green, RC Gur, L Lin, BR Macias, ...
Science 364 (6436), eaau8650, 2019
8212019
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
O Abdel-Wahab, M Adli, LM LaFave, J Gao, T Hricik, AH Shih, S Pandey, ...
Cancer cell 22 (2), 180-193, 2012
6762012
The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee
E Campo, ES Jaffe, JR Cook, L Quintanilla-Martinez, SH Swerdlow, ...
Blood, The Journal of the American Society of Hematology 140 (11), 1229-1253, 2022
6172022
IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ...
Nature 488 (7413), 656-659, 2012
6022012
DNMT1-interacting RNAs block gene-specific DNA methylation
A Di Ruscio, AK Ebralidze, T Benoukraf, G Amabile, LA Goff, J Terragni, ...
Nature 503 (7476), 371-376, 2013
5622013
Comparative isoschizomer profiling of cytosine methylation: the HELP assay
B Khulan, RF Thompson, K Ye, MJ Fazzari, M Suzuki, E Stasiek, ...
Genome research 16 (8), 1046-1055, 2006
4752006
Outcome of deferred initial therapy in mantle-cell lymphoma
P Martin, A Chadburn, P Christos, K Weil, RR Furman, J Ruan, R Elstrom, ...
J Clin Oncol 27 (8), 1209-1213, 2009
4202009
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ...
Nature medicine 21 (10), 1199-1208, 2015
4152015
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