Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma F Li, MK Shanmugam, L Chen, S Chatterjee, J Basha, AP Kumar, ... Cancer prevention research 6 (8), 843-854, 2013 | 185 | 2013 |
Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways R Kannaiyan, KA Manu, L Chen, F Li, P Rajendran, A Subramaniam, ... Apoptosis 16, 1028-1041, 2011 | 178 | 2011 |
Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products KA Manu, MK Shanmugam, F Li, L Chen, KS Siveen, KS Ahn, AP Kumar, ... Journal of molecular medicine 92, 267-276, 2014 | 153 | 2014 |
Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3 A Subramaniam, MK Shanmugam, TH Ong, F Li, E Perumal, L Chen, ... British journal of pharmacology 170 (4), 807-821, 2013 | 150 | 2013 |
Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo P Rajendran, TH Ong, L Chen, F Li, MK Shanmugam, S Vali, T Abbasi, ... Clinical cancer research 17 (6), 1425-1439, 2011 | 142 | 2011 |
Targeting PPARγ signaling cascade for the prevention and treatment of prostate cancer S Sikka, L Chen, G Sethi, AP Kumar PPAR research 2012, 2012 | 85 | 2012 |
Dual functionalized bacteriophage Qβ as a photocaged drug carrier Z Chen, N Li, L Chen, J Lee, JJ Gassensmith Small 12 (33), 4563-4571, 2016 | 58 | 2016 |
PPARγ ligand–induced annexin A1 expression determines chemotherapy response via deubiquitination of death domain kinase RIP in triple-negative breast cancers L Chen, Y Yuan, S Kar, MM Kanchi, S Arora, JE Kim, PF Koh, E Yousef, ... Molecular Cancer Therapeutics 16 (11), 2528-2542, 2017 | 37 | 2017 |
A Forkhead box protein C2 inhibitor: targeting epithelial–mesenchymal transition and cancer metastasis M Castaneda, L Chen, L Pradhan, S Li, R Zein, Y Lee, HS Lim, HJ Nam, ... Chembiochem 19 (13), 1359-1364, 2018 | 19 | 2018 |
Novel cell-penetrating-amyloid peptide conjugates preferentially kill cancer cells JR Veloria, L Chen, L Li, GAM Breen, J Lee, WJ Goux Medchemcomm 9 (1), 121-130, 2018 | 15 | 2018 |
Discovering alkylamide derivatives of bexarotene as new therapeutic agents against triple-negative breast cancer L Chen, C Long, J Nguyen, D Kumar, J Lee Bioorganic & medicinal chemistry letters 28 (3), 420-424, 2018 | 12 | 2018 |
A synthetic binder of breast cancer stem cells L Chen, C Long, KAM Tran, J Lee Chemistry–A European Journal 24 (15), 3694-3698, 2018 | 7 | 2018 |
A phenotypic cell-binding screen identifies a novel compound targeting triple-negative breast cancer L Chen, C Long, J Youn, J Lee ACS Combinatorial Science 20 (6), 330-334, 2018 | 3 | 2018 |
Facile synthesis of autophagonizer and evaluation of its activity to induce autophagic cell death in apoptosis-defective cell line J Nguyen, L Chen, D Kumar, J Lee Bioorganic & Medicinal Chemistry Letters 26 (19), 4753-4756, 2016 | 1 | 2016 |
Synthetic small molecule targeting CD24-/CD44+/ALDH+ cell population inhibits cancer stem cell activities in breast cancer L Chen, C Long, KA Tran, J Lee Cancer Research 77 (13_Supplement), 3899-3899, 2017 | | 2017 |
Isorhamnetin modulates PPARδ activation pathway leading to the suppression of proliferation, invasion and induction of apoptosis in gastric cancer L Ramachandran, MK Aryan, C Luxi, L Feng, P Rajendran, CW Yap, ... Cancer Research 72 (8_Supplement), 1978-1978, 2012 | | 2012 |
1047 POSTER Annexin-A1 Mediates Chemosensitivity to PPAR-gamma Ligands in Mammary Carcinoma: a Novel Biomarker for Effective Tailoring of Patients to PPAR-gamma Ligand Therapy L Chen, PF Koh, HK Lim, AP Kumar European Journal of Cancer, S110, 2011 | | 2011 |