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Chuanxin Huang
Chuanxin Huang
Adresă de e-mail confirmată pe shsmu.edu.cn
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Recurrent gain-of-function USP8 mutations in Cushing's disease
ZY Ma, ZJ Song, JH Chen, YF Wang, SQ Li, LF Zhou, Y Mao, YM Li, ...
Cell research 25 (3), 306-317, 2015
3252015
Anti-tumor effect of β-elemene in glioblastoma cells depends on p38 MAPK activation
YQ Yao, X Ding, YC Jia, CX Huang, YZ Wang, YH Xu
Cancer letters 264 (1), 127-134, 2008
2372008
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters
K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ...
Cell reports 4 (3), 578-588, 2013
1922013
The genome-wide mutational landscape of pituitary adenomas
ZJ Song, ZJ Reitman, ZY Ma, JH Chen, QL Zhang, XF Shou, CX Huang, ...
Cell research 26 (11), 1255-1259, 2016
1372016
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms
C Huang, K Hatzi, A Melnick
Nature immunology 14 (4), 380-388, 2013
1342013
Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia
H Geng, C Hurtz, KB Lenz, Z Chen, D Baumjohann, S Thompson, ...
Cancer cell 27 (3), 409-425, 2015
1302015
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint
S Swaminathan, C Huang, H Geng, Z Chen, R Harvey, H Kang, C Ng, ...
Nature medicine 19 (8), 1014-1022, 2013
1202013
Identification of recurrent USP48 and BRAF mutations in Cushing’s disease
J Chen, X Jian, S Deng, Z Ma, X Shou, Y Shen, Q Zhang, Z Song, Z Li, ...
Nature communications 9 (1), 3171, 2018
1182018
Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation
C Huang, H Geng, I Boss, L Wang, A Melnick
Blood, The Journal of the American Society of Hematology 123 (7), 1012-1020, 2014
1172014
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia
B Kharabi Masouleh, H Geng, C Hurtz, LN Chan, AC Logan, MS Chang, ...
Proceedings of the National Academy of Sciences 111 (21), E2219-E2228, 2014
1022014
SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation
X Yu, Y Lao, XL Teng, S Li, Y Zhou, F Wang, X Guo, S Deng, Y Chang, ...
Nature communications 9 (1), 3157, 2018
932018
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia
H Geng, S Brennan, TA Milne, WY Chen, Y Li, C Hurtz, SM Kweon, L Zickl, ...
Cancer discovery 2 (11), 1004-1023, 2012
902012
The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers
C Huang, DG Gonzalez, CM Cote, Y Jiang, K Hatzi, M Teater, K Dai, T Hla, ...
Cell reports 8 (5), 1497-1508, 2014
852014
HDAC3 inhibition upregulates PD-L1 expression in B-cell lymphomas and augments the efficacy of anti–PD-L1 therapy
S Deng, Q Hu, H Zhang, F Yang, C Peng, C Huang
Molecular cancer therapeutics 18 (5), 900-908, 2019
842019
PTEN C-terminal deletion causes genomic instability and tumor development
Z Sun, C Huang, J He, KL Lamb, X Kang, T Gu, WH Shen, Y Yin
Cell reports 6 (5), 844-854, 2014
842014
Excessive CD11c+ Tbet+ B cells promote aberrant TFH differentiation and affinity-based germinal center selection in lupus
W Zhang, H Zhang, S Liu, F Xia, Z Kang, Y Zhang, Y Liu, H Xiao, L Chen, ...
Proceedings of the National Academy of Sciences 116 (37), 18550-18560, 2019
782019
Germline mutations in CDH23, encoding cadherin-related 23, are associated with both familial and sporadic pituitary adenomas
Q Zhang, C Peng, J Song, Y Zhang, J Chen, Z Song, X Shou, Z Ma, ...
The American Journal of Human Genetics 100 (5), 817-823, 2017
652017
Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin‐B‐cell lymphoma 6 signaling
KH Park‐Min, EY Lee, NK Moskowitz, E Lim, SK Lee, JA Lorenzo, ...
Journal of Bone and Mineral Research 28 (1), 135-149, 2013
632013
The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity
H Peng, F Yang, Q Hu, J Sun, C Peng, Y Zhao, C Huang
Autophagy 16 (4), 698-708, 2020
622020
Characterization of ZNF23, a KRAB-containing protein that is downregulated in human cancers and inhibits cell cycle progression
C Huang, Y Jia, S Yang, B Chen, H Sun, F Shen, Y Wang
Experimental cell research 313 (2), 254-263, 2007
532007
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