ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ... Neuron 88 (4), 678-690, 2015 | 769 | 2015 |
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions S Qamar, GZ Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, ... Cell 173 (3), 720-734. e15, 2018 | 687 | 2018 |
Dynamic axonal translation in developing and mature visual circuits T Shigeoka, H Jung, J Jung, B Turner-Bridger, J Ohk, JQ Lin, PS Amieux, ... Cell 166 (1), 181-192, 2016 | 400 | 2016 |
Late endosomes act as mRNA translation platforms and sustain mitochondria in axons JM Cioni, JQ Lin, AV Holtermann, M Koppers, MAH Jakobs, A Azizi, ... Cell 176 (1-2), 56-72. e15, 2019 | 319 | 2019 |
RNA docking and local translation regulate site-specific axon remodeling in vivo HHW Wong, JQ Lin, F Ströhl, CG Roque, JM Cioni, R Cagnetta, ... Neuron 95 (4), 852-868. e8, 2017 | 146 | 2017 |
On-site ribosome remodeling by locally synthesized ribosomal proteins in axons T Shigeoka, M Koppers, HHW Wong, JQ Lin, R Cagnetta, A Dwivedy, ... Cell Reports 29 (11), 3605-3619. e10, 2019 | 114 | 2019 |
The physiological and pathological biophysics of phase separation and gelation of RNA binding proteins in amyotrophic lateral sclerosis and fronto-temporal lobar degeneration P St George-Hyslop, JQ Lin, A Miyashita, EC Phillips, S Qamar, ... Brain research 1693, 11-23, 2018 | 67 | 2018 |
The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes M Lu, FW van Tartwijk, JQ Lin, W Nijenhuis, P Parutto, M Fantham, ... Science Advances 6 (51), eabc7209, 2020 | 62 | 2020 |
Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons M Koppers, R Cagnetta, T Shigeoka, LCS Wunderlich, P Vallejo-Ramirez, ... Elife 8, e48718, 2019 | 58 | 2019 |
Single molecule translation imaging visualizes the dynamics of local β-actin synthesis in retinal axons F Ströhl, JQ Lin, RF Laine, HHW Wong, V Urbančič, R Cagnetta, CE Holt, ... Scientific reports 7 (1), 709, 2017 | 47 | 2017 |
Cue-polarized transport of β-actin mRNA depends on 3′ UTR and microtubules in live growth cones KM Leung, B Lu, HHW Wong, JQ Lin, B Turner-Bridger, CE Holt Frontiers in Cellular Neuroscience 12, 2018 | 30 | 2018 |
Tumor protein Tctp regulates axon development in the embryonic visual system CG Roque, HHW Wong, JQ Lin, CE Holt Development 143 (7), 1134-1148, 2016 | 29 | 2016 |
Axonal mRNA translation in neurological disorders JQ Lin, FW van Tartwijk, CE Holt RNA biology, 1-26, 2020 | 21 | 2020 |
A waveguide imaging platform for live‐cell TIRF imaging of neurons over large fields of view IS Opstad, F Ströhl, M Fantham, C Hockings, O Vanderpoorten, ... Journal of biophotonics 13 (6), e201960222, 2020 | 15 | 2020 |
HNRNPH1 regulates the neuroprotective cold‐shock protein RBM3 expression through poison exon exclusion JQ Lin, D Khuperkar, S Pavlou, S Makarchuk, N Patikas, FCY Lee, ... The EMBO Journal, e113168, 2023 | 5 | 2023 |
Mutation of the ALS/FTD-associated RNA-binding protein FUS alters axonal cytoskeletal organisation FW van Tartwijk, LCS Wunderlich, I Mela, S Makarchuk, MAH Jakobs, ... bioRxiv, 2022.10. 04.510780, 2022 | 1 | 2022 |
Live Imaging of RNA Transport and Translation in Xenopus Retinal Axons JQ Lin, JM Cioni Axonal Transport: Methods and Protocols, 49-69, 2022 | 1 | 2022 |
Enrichment of the local synaptic translatome for genetic risk associated with schizophrenia and autism spectrum disorder NE Clifton, JQ Lin, CE Holt, MC O'Donovan, J Mill medRxiv, 2023.10. 19.23297263, 2023 | | 2023 |
T112. PARTITIONING THE EFFECTS OF PSYCHIATRIC RISK VARIANTS ON THE LOCAL SYNAPTIC TRANSLATOME N Clifton, J Lin, E Rees, J Mill, M O'Donovan European Neuropsychopharmacology 63, e229-e230, 2022 | | 2022 |
The DCC receptor and its endosome associated role for regulating local protein synthesis LC Wunderlich, F van Tartwijk, JQ Lin, M Koppers, M Barysevich, ... Biophysical Journal 121 (3), 154a, 2022 | | 2022 |