Stefano Santaguida
Stefano Santaguida
Group Leader and Associate Professor - European Institute of Oncology and University of Milan
Verified email at - Homepage
Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy, 1-382, 2021
Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex
C Ciferri, S Pasqualato, E Screpanti, G Varetti, S Santaguida, G Dos Reis, ...
Cell 133 (3), 427-439, 2008
The life and miracles of kinetochores
S Santaguida, A Musacchio
The EMBO journal 28 (17), 2511-2531, 2009
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
S Santaguida, A Tighe, AM D'Alise, SS Taylor, A Musacchio
Journal of Cell Biology 190 (1), 73-87, 2010
Short-and long-term effects of chromosome mis-segregation and aneuploidy
S Santaguida, A Amon
Nature reviews Molecular cell biology 16 (8), 473-485, 2015
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex
L Hewitt, A Tighe, S Santaguida, AM White, CD Jones, A Musacchio, ...
Journal of Cell Biology 190 (1), 25-34, 2010
Chromosome mis-segregation generates cell-cycle-arrested cells with complex karyotypes that are eliminated by the immune system
S Santaguida, A Richardson, DR Iyer, O M'Saad, L Zasadil, KA Knouse, ...
Developmental cell 41 (6), 638-651. e5, 2017
The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint
M Mapelli, L Massimiliano, S Santaguida, A Musacchio
Cell 131 (4), 730-743, 2007
The MIS12 complex is a protein interaction hub for outer kinetochore assembly
A Petrovic, S Pasqualato, P Dube, V Krenn, S Santaguida, D Cittaro, ...
Journal of Cell Biology 190 (5), 835-852, 2010
Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction
S Santaguida, C Vernieri, F Villa, A Ciliberto, A Musacchio
The EMBO journal 30 (8), 1508-1519, 2011
Side by side comparison between dynamic versus static models of blood–brain barrier in vitro: a permeability study
S Santaguida, D Janigro, M Hossain, E Oby, E Rapp, L Cucullo
Brain research 1109 (1), 1-13, 2006
Aneuploidy-induced cellular stresses limit autophagic degradation
S Santaguida, E Vasile, E White, A Amon
Genes & development 29 (19), 2010-2021, 2015
Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction
V Krenn, A Wehenkel, X Li, S Santaguida, A Musacchio
Journal of Cell Biology 196 (4), 451-467, 2012
Homeostatic control of mitotic arrest
G Varetti, C Guida, S Santaguida, E Chiroli, A Musacchio
Molecular cell 44 (5), 710-720, 2011
A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B
A De Antoni, S Maffini, S Knapp, A Musacchio, S Santaguida
Journal of Cell Biology 199 (2), 269-284, 2012
Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery
F Civril, A Wehenkel, FM Giorgi, S Santaguida, A Di Fonzo, G Grigorean, ...
Structure 18 (5), 616-626, 2010
Crystal structure of human aurora B in complex with INCENP and VX-680
JM Elkins, S Santaguida, A Musacchio, S Knapp
Journal of medicinal chemistry 55 (17), 7841-7848, 2012
Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition
Y Cohen-Sharir, JM McFarland, M Abdusamad, C Marquis, SV Bernhard, ...
Nature 590 (7846), 486-491, 2021
Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells
CM Brennan, LP Vaites, JN Wells, S Santaguida, JA Paulo, Z Storchova, ...
Genes & development 33 (15-16), 1031-1047, 2019
A general framework for inhibitor resistance in protein kinases
D Balzano, S Santaguida, A Musacchio, F Villa
Chemistry & biology 18 (8), 966-975, 2011
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