|RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3|
L Tavares, E Dimitrova, D Oxley, J Webster, R Poot, J Demmers, ...
Cell 148 (4), 664-678, 2012
|The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements|
S Schoenfelder, M Furlan-Magaril, B Mifsud, F Tavares-Cadete, R Sugar, ...
Genome Research 25 (4), 582-597, 2015
|Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome|
S Schoenfelder, R Sugar, A Dimond, BM Javierre, H Armstrong, B Mifsud, ...
Nature genetics 47 (10), 1179-1186, 2015
|Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment|
S Cooper, M Dienstbier, R Hassan, L Schermelleh, J Sharif, ...
Cell reports 7 (5), 1456-1470, 2014
|Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells|
SS Taylor, D Hussein, Y Wang, S Elderkin, CJ Morrow
Journal of cell science 114 (24), 4385-4395, 2001
|Ubiquitin‐specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor|
GN Maertens, S El Messaoudi‐Aubert, S Elderkin, K Hiom, G Peters
The EMBO journal 29 (15), 2553-2565, 2010
|Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP–aluminum fluoride: insights into activator mechanochemical action|
M Chaney, R Grande, SR Wigneshweraraj, W Cannon, P Casaz, ...
Genes & development 15 (17), 2282-2294, 2001
|A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin|
S Elderkin, GN Maertens, M Endoh, DL Mallery, N Morrice, H Koseki, ...
Molecular cell 28 (1), 107-120, 2007
|Mechanism of action of the Escherichia coli phage shock protein PspA in repression of the AAA family transcription factor PspF|
S Elderkin, S Jones, J Schumacher, D Studholme, M Buck
Journal of molecular biology 320 (1), 23-37, 2002
|Organization of the AAA+ adaptor protein PspA is an oligomeric ring|
BD Hankamer, SL Elderkin, M Buck, J Nield
Journal of Biological Chemistry 279 (10), 8862-8866, 2004
|The histone-fold protein complex CHRAC-15/17 enhances nucleosome sliding and assembly mediated by ACF|
I Kukimoto, S Elderkin, M Grimaldi, T Oelgeschläger, PD Varga-Weisz
Molecular cell 13 (2), 265-277, 2004
|Molecular determinants for PspA-mediated repression of the AAA transcriptional activator PspF|
S Elderkin, P Bordes, S Jones, M Rappas, M Buck
Journal of bacteriology 187 (9), 3238-3248, 2005
|Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression|
G Kar, JK Kim, AA Kolodziejczyk, KN Natarajan, E Torlai Triglia, B Mifsud, ...
Nature communications 8 (1), 36, 2017
|The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells|
CL Novo, C Tang, K Ahmed, U Djuric, E Fussner, NP Mullin, NP Morgan, ...
Genes & development 30 (9), 1101-1115, 2016
|Fission yeast Iec1-ino80-mediated nucleosome eviction regulates nucleotide and phosphate metabolism|
CJ Hogan, S Aligianni, M Durand-Dubief, J Persson, WR Will, J Webster, ...
Molecular and cellular biology 30 (3), 657-674, 2010
|Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells|
H Koohy, DJ Bolland, LS Matheson, S Schoenfelder, C Stellato, A Dimond, ...
Genome biology 19 (1), 1-24, 2018
|Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system|
L Bruno, V Ramlall, RA Studer, S Sauer, D Bradley, G Dharmalingam, ...
Nature immunology 20 (10), 1372-1380, 2019
L Matheson, S Elderkin
Nuclear architecture and dynamics, 297-320, 2018
|13.1 Diversity of Polycomb Repressive Complexes|
L Matheson, S Elderkin
Nuclear Architecture and Dynamics 2, 297, 2017
|Details of Projects for 2010|
G Butcher, M Coleman, F Colucci, S Cook, A Corcoran, S Elderkin, ...