| Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy A Wacker, JE Weigand, SR Akabayov, N Altincekic, JK Bains, ... Nucleic acids research 48 (22), 12415-12435, 2020 | 131 | 2020 |
| Mapping the landscape of RNA dynamics with NMR spectroscopy J Rinnenthal, J Buck, J Ferner, A Wacker, B FÜrtig, H Schwalbe Accounts of chemical research 44 (12), 1292-1301, 2011 | 91 | 2011 |
| Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes A Garcia-Lopez, F Tessaro, HRA Jonker, A Wacker, C Richter, A Comte, ... Nature communications 9 (1), 2032, 2018 | 65 | 2018 |
| Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS‐CoV‐2 Genome S Sreeramulu, C Richter, H Berg, MA Wirtz Martin, B Ceylan, T Matzel, ... Angewandte Chemie 133 (35), 19340-19349, 2021 | 61 | 2021 |
| Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation H Steinert, F Sochor, A Wacker, J Buck, C Helmling, F Hiller, S Keyhani, ... Elife 6, e21297, 2017 | 54 | 2017 |
| Life times of metastable states guide regulatory signaling in transcriptional riboswitches C Helmling, DP Klötzner, F Sochor, RA Mooney, A Wacker, R Landick, ... Nature Communications 9 (1), 944, 2018 | 47 | 2018 |
| NMR structural profiling of transcriptional intermediates reveals riboswitch regulation by metastable RNA conformations C Helmling, A Wacker, MT Wolfinger, IL Hofacker, M Hengesbach, ... Journal of the American Chemical Society 139 (7), 2647-2656, 2017 | 47 | 2017 |
| Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR-spectroscopy A Wacker, J Buck, D Mathieu, C Richter, J Wöhnert, H Schwalbe Nucleic acids research 39 (15), 6802-6812, 2011 | 46 | 2011 |
| Influence of ground-state structure and Mg 2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain J Buck, A Wacker, E Warkentin, J Wöhnert, J Wirmer-Bartoschek, ... Nucleic acids research 39 (22), 9768-9778, 2011 | 32 | 2011 |
| 13C-direct detected NMR experiments for the sequential J-based resonance assignment of RNA oligonucleotides C Richter, H Kovacs, J Buck, A Wacker, B Fürtig, W Bermel, H Schwalbe Journal of biomolecular NMR 47, 259-269, 2010 | 32 | 2010 |
| 19F NMR‐Based Fragment Screening for 14 Different Biologically Active RNAs and 10 DNA and Protein Counter‐Screens O Binas, V de Jesus, T Landgraf, AE Völklein, J Martins, D Hymon, ... ChemBioChem 22 (2), 423-433, 2021 | 30 | 2021 |
| In‐Cell NMR Spectroscopy of Functional Riboswitch Aptamers in Eukaryotic Cells P Broft, S Dzatko, M Krafcikova, A Wacker, R Hänsel‐Hertsch, V Dötsch, ... Angewandte Chemie International Edition 60 (2), 865-872, 2021 | 29 | 2021 |
| Noncovalent spin labeling of riboswitch RNAs to obtain long-range structural NMR restraints C Helmling, I Bessi, A Wacker, KA Schnorr, HRA Jonker, C Richter, ... ACS Chemical Biology 9 (6), 1330-1339, 2014 | 22 | 2014 |
| 1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b F Cantini, L Banci, N Altincekic, JK Bains, K Dhamotharan, C Fuks, ... Biomolecular NMR assignments 14, 339-346, 2020 | 19 | 2020 |
| Impact of spin label rigidity on extent and accuracy of distance information from PRE data KA Schnorr, DB Gophane, C Helmling, E Cetiner, K Pasemann, B Fürtig, ... Journal of Biomolecular NMR 68, 53-63, 2017 | 14 | 2017 |
| Ligand binding to 2΄-deoxyguanosine sensing riboswitch in metabolic context YB Kim, A Wacker, K Laer, VV Rogov, B Suess, H Schwalbe Nucleic Acids Research 45 (9), 5375-5386, 2017 | 12 | 2017 |
| Mechanisms for differentiation between cognate and near-cognate ligands by purine riboswitches A Wacker, J Buck, C Richter, H Schwalbe, J Wöhnert RNA biology 9 (5), 672-680, 2012 | 12 | 2012 |
| Comprehensive fragment screening of the SARS‐CoV‐2 proteome explores novel chemical space for drug development H Berg, MA Wirtz Martin, N Altincekic, I Alshamleh, J Kaur Bains, ... Angewandte Chemie International Edition 61 (46), e202205858, 2022 | 11 | 2022 |
| 1H, 13C, 15N and 31P chemical shift assignment for stem-loop 4 from the 5′-UTR of SARS-CoV-2 J Vögele, JP Ferner, N Altincekic, JK Bains, B Ceylan, B Fürtig, JT Grün, ... Biomolecular NMR assignments 15 (2), 335-340, 2021 | 10 | 2021 |
| 1H, 13C and 15N chemical shift assignment of the stem-loop 5a from the 5′-UTR of SARS-CoV-2 R Schnieders, SA Peter, E Banijamali, M Riad, N Altincekic, JK Bains, ... Biomolecular NMR assignments 15, 203-211, 2021 | 9 | 2021 |
Harald SchwalbeGoethe-University FrankfurtVerified email at nmr.uni-frankfurt.de
