Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation SP Parihar, R Guler, R Khutlang, DM Lang, R Hurdayal, MM Mhlanga, ... The Journal of infectious diseases 209 (5), 754-763, 2014 | 321 | 2014 |
Batf2/Irf1 induces inflammatory responses in classically activated macrophages, lipopolysaccharides, and mycobacterial infection S Roy, R Guler, SP Parihar, S Schmeier, B Kaczkowski, H Nishimura, ... The Journal of Immunology 194 (12), 6035-6044, 2015 | 103 | 2015 |
Allergic airway disease is unaffected by the absence of IL-4Rα–dependent alternatively activated macrophages NE Nieuwenhuizen, F Kirstein, J Jayakumar, B Emedi, R Hurdayal, ... Journal of Allergy and Clinical Immunology 130 (3), 743-750. e8, 2012 | 71 | 2012 |
The role of IL-4 and IL-13 in cutaneous Leishmaniasis R Hurdayal, F Brombacher Immunology letters 161 (2), 179-183, 2014 | 64 | 2014 |
Deletion of IL-4 Receptor Alpha on Dendritic Cells Renders BALB/c Mice Hypersusceptible to Leishmania major Infection R Hurdayal, NE Nieuwenhuizen, M Revaz-Breton, L Smith, JC Hoving, ... PLoS pathogens 9 (10), e1003699, 2013 | 61 | 2013 |
IL-4–producing B cells regulate T helper cell dichotomy in type 1-and type 2-controlled diseases R Hurdayal, HH Ndlovu, M Revaz-Breton, SP Parihar, JK Nono, ... Proceedings of the National Academy of Sciences 114 (40), E8430-E8439, 2017 | 52 | 2017 |
Anti-peptide antibodies differentiate between plasmodial lactate dehydrogenases R Hurdayal, I Achilonu, D Choveaux, THT Coetzer, JPD Goldring Peptides 31 (4), 525-532, 2010 | 48 | 2010 |
Protein kinase C-delta (PKCδ), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and … SP Parihar, M Ozturk, MJ Marakalala, DT Loots, R Hurdayal, ... Mucosal immunology 11 (2), 496-511, 2018 | 46 | 2018 |
Interleukin-4 receptor alpha: from innate to adaptive immunity in murine models of cutaneous leishmaniasis R Hurdayal, F Brombacher Frontiers in immunology 8, 297005, 2017 | 40 | 2017 |
Topical simvastatin as host-directed therapy against severity of cutaneous leishmaniasis in mice SP Parihar, MA Hartley, R Hurdayal, R Guler, F Brombacher Scientific reports 6 (1), 33458, 2016 | 36 | 2016 |
Plasmodium glyceraldehyde-3-phosphate dehydrogenase: a potential malaria diagnostic target RGE Krause, R Hurdayal, D Choveaux, JM Przyborski, THT Coetzer, ... Experimental parasitology 179, 7-19, 2017 | 35 | 2017 |
Can we harness immune responses to improve drug treatment in leishmaniasis? RT Aruleba, KC Carter, F Brombacher, R Hurdayal Microorganisms 8 (7), 1069, 2020 | 22 | 2020 |
Dendritic Cell-Mediated Vaccination Relies on Interleukin-4 Receptor Signaling to Avoid Tissue Damage after Leishmania major Infection of BALB/c Mice A Masic, R Hurdayal, NE Nieuwenhuizen, F Brombacher, H Moll PLoS neglected tropical diseases 6 (7), e1721, 2012 | 22 | 2012 |
Unravelling the unsolved paradoxes of cytokine families in host resistance and susceptibility to Leishmania infection BO Osero, RT Aruleba, F Brombacher, R Hurdayal Cytokine: X 2 (4), 100043, 2020 | 18 | 2020 |
IL-4 mediated resistance of BALB/c mice to visceral leishmaniasis is independent of IL-4Rα signaling via T cells E McFarlane, T Mokgethi, PM Kaye, R Hurdayal, F Brombacher, ... Frontiers in immunology 10, 478635, 2019 | 14 | 2019 |
Inflammatory Dendritic Cells, Regulated by IL-4 Receptor Alpha Signaling, Control Replication, and Dissemination of Leishmania major in Mice R Hurdayal, NE Nieuwenhuizen, R Khutlang, F Brombacher Frontiers in cellular and infection microbiology 9, 479, 2020 | 13 | 2020 |
IL-4Rα Signaling in Keratinocytes and Early IL-4 Production Are Dispensable for Generating a Curative T Helper 1 Response in Leishmania major-Infected C57BL … M Descatoire, BP Hurrell, M Govender, K Passelli, B Martinez-Salazar, ... Frontiers in immunology 8, 1265, 2017 | 13 | 2017 |
Deletion of interleukin-4 receptor alpha-responsive keratinocytes in BALB/c mice does not alter susceptibility to cutaneous leishmaniasis M Govender, R Hurdayal, B Martinez-Salazar, K Gqada, S Pillay, ... Infection and immunity 86 (12), 10.1128/iai. 00710-18, 2018 | 11 | 2018 |
Darunavir disrupts critical nodes in metastable 2019-nCoV-RBD/ACE-2 complex OI Omotuyi, O Nash, BO Ajiboye, DS Metibemu, BE Oyinloye, ... Preprints, 2020 | 10 | 2020 |
Interleukin-4 responsive dendritic cells are dispensable to host resistance against leishmania mexicana infection BO Osero, Z Cele, RT Aruleba, RA Maine, M Ozturk, MB Lutz, ... Frontiers in Immunology 12, 759021, 2022 | 2 | 2022 |