| Matrigel: a complex protein mixture required for optimal growth of cell culture CS Hughes, LM Postovit, GA Lajoie Proteomics 10 (9), 1886-1890, 2010 | 1682 | 2010 |
| Ultrasensitive proteome analysis using paramagnetic bead technology CS Hughes, S Foehr, DA Garfield, EE Furlong, LM Steinmetz, J Krijgsveld Molecular systems biology 10 (10), 757, 2014 | 978 | 2014 |
| Single-pot, solid-phase-enhanced sample preparation for proteomics experiments CS Hughes, S Moggridge, T Müller, PH Sorensen, GB Morin, J Krijgsveld Nature protocols 14 (1), 68-85, 2019 | 952 | 2019 |
| Prevention of amino acid conversion in SILAC experiments with embryonic stem cells SC Bendall, C Hughes, MH Stewart, B Doble, M Bhatia, GA Lajoie Molecular & Cellular Proteomics 7 (9), 1587-1597, 2008 | 234 | 2008 |
| Extending the compatibility of the SP3 paramagnetic bead processing approach for proteomics S Moggridge, PH Sorensen, GB Morin, CS Hughes Journal of proteome research 17 (4), 1730-1740, 2018 | 208 | 2018 |
| Identification of maturation-specific proteins by single-cell proteomics of human oocytes I Virant-Klun, S Leicht, C Hughes, J Krijgsveld Molecular & Cellular Proteomics 15 (8), 2616-2627, 2016 | 193 | 2016 |
| CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion JF Tien, A Mazloomian, SWG Cheng, CS Hughes, CCT Chow, LT Canapi, ... Nucleic acids research 45 (11), 6698-6716, 2017 | 140 | 2017 |
| Quantitative profiling of single formalin fixed tumour sections: proteomics for translational research CS Hughes, MK McConechy, DR Cochrane, T Nazeran, AN Karnezis, ... Scientific reports 6 (1), 34949, 2016 | 129 | 2016 |
| High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry J Wu, CS Hughes, P Picard, S Letarte, M Gaudreault, JF Lévesque, ... Analytical Chemistry 79 (12), 4657-4665, 2007 | 123 | 2007 |
| An enhanced mass spectrometry approach reveals human embryonic stem cell growth factors in culture SC Bendall, C Hughes, JL Campbell, MH Stewart, P Pittock, S Liu, ... Molecular & Cellular Proteomics 8 (3), 421-432, 2009 | 110 | 2009 |
| De novo sequencing methods in proteomics C Hughes, B Ma, GA Lajoie Proteome Bioinformatics, 105-121, 2010 | 108 | 2010 |
| Class I HDAC inhibitors enhance YB‐1 acetylation and oxidative stress to block sarcoma metastasis AM El‐Naggar, SP Somasekharan, Y Wang, H Cheng, GL Negri, M Pan, ... EMBO reports 20 (12), e48375, 2019 | 84 | 2019 |
| Proteomic analysis of extracellular matrices used in stem cell culture CS Hughes, L Radan, D Betts, LM Postovit, GA Lajoie Proteomics 11 (20), 3983-3991, 2011 | 59 | 2011 |
| Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes K Asleh, GL Negri, SE Spencer Miko, S Colborne, CS Hughes, XQ Wang, ... Nature Communications 13 (1), 896, 2022 | 56 | 2022 |
| Translational capacity of a cell is determined during transcription elongation via the Ccr4-Not complex I Gupta, Z Villanyi, S Kassem, C Hughes, OO Panasenko, LM Steinmetz, ... Cell reports 15 (8), 1782-1794, 2016 | 53 | 2016 |
| CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor T Funnell, S Tasaki, A Oloumi, S Araki, E Kong, D Yap, Y Nakayama, ... Nature Communications 8 (1), 7, 2017 | 52 | 2017 |
| Mass spectrometry–based proteomic analysis of the matrix microenvironment in pluripotent stem cell culture C Hughes, L Radan, WY Chang, WL Stanford, DH Betts, LM Postovit, ... Molecular & Cellular Proteomics 11 (12), 1924-1936, 2012 | 52 | 2012 |
| Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma HF Zhang, CS Hughes, W Li, JZ He, D Surdez, AM El-Naggar, H Cheng, ... Cancer discovery 11 (11), 2884-2903, 2021 | 51 | 2021 |
| Human fibroblast matrices bio‐assembled under macromolecular crowding support stable propagation of human embryonic stem cells Y Peng, MT Bocker, J Holm, WS Toh, CS Hughes, F Kidwai, GA Lajoie, ... Journal of tissue engineering and regenerative medicine 6 (10), e74-e86, 2012 | 40 | 2012 |
| Microenvironmental regulation of telomerase isoforms in human embryonic stem cells L Radan, CS Hughes, JH Teichroeb, FM Vieira Zamora, M Jewer, ... Stem cells and development 23 (17), 2046-2066, 2014 | 38 | 2014 |
