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Zuanning Yuan
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Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation
R Georgescu, Z Yuan, L Bai, R de Luna Almeida Santos, J Sun, D Zhang, ...
Proceedings of the National Academy of Sciences 114 (5), E697-E706, 2017
1912017
The architecture of a eukaryotic replisome
J Sun, Y Shi, RE Georgescu, Z Yuan, BT Chait, H Li, ME O'donnell
Nature structural & molecular biology 22 (12), 976-982, 2015
1842015
Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation
Z Yuan, L Bai, J Sun, R Georgescu, J Liu, ME O'donnell, H Li
Nature structural & molecular biology 23 (3), 217-224, 2016
1442016
Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1
Z Yuan, A Riera, L Bai, J Sun, S Nandi, C Spanos, ZA Chen, M Barbon, ...
Nature structural & molecular biology 24 (3), 316-324, 2017
1382017
Structural and mechanistic insights into Mcm2–7 double-hexamer assembly and function
J Sun, A Fernandez-Cid, A Riera, S Tognetti, Z Yuan, B Stillman, C Speck, ...
Genes & development 28 (20), 2291-2303, 2014
1222014
Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model
Y Noguchi, Z Yuan, L Bai, S Schneider, G Zhao, B Stillman, C Speck, H Li
Proceedings of the National Academy of Sciences 114 (45), E9529-E9538, 2017
802017
Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome
Z Yuan, R Georgescu, GD Schauer, ME O’Donnell, H Li
Nature communications 11 (1), 3156, 2020
642020
DNA unwinding mechanism of a eukaryotic replicative CMG helicase
Z Yuan, R Georgescu, L Bai, D Zhang, H Li, ME O’Donnell
Nature communications 11 (1), 688, 2020
552020
Ctf4 organizes sister replisomes and Pol α into a replication factory
Z Yuan, R Georgescu, RLA Santos, D Zhang, L Bai, NY Yao, G Zhao, ...
Elife 8, e47405, 2019
512019
Structure of the active form of human origin recognition complex and its ATPase motor module
A Tocilj, KF On, Z Yuan, J Sun, E Elkayam, H Li, B Stillman, L Joshua-Tor
Elife 6, e20818, 2017
482017
Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation
P Gupta, NC Gauthier, Y Cheng-Han, Y Zuanning, B Pontes, M Ohmstede, ...
Biology Open 2 (12), 1288-1299, 2013
422013
Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6
Z Yuan, S Schneider, T Dodd, A Riera, L Bai, C Yan, M Barbon, ...
Proceedings of the National Academy of Sciences 117 (30), 17747-17756, 2020
392020
Biochemical and structural analysis of Gox2181, a new member of the SDR superfamily from Gluconobacter oxydans
X Liu, Z Yuan, YA Yuan, J Lin, D Wei
Biochemical and Biophysical Research Communications 415 (2), 410-415, 2011
262011
Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD
M Du, Z Yuan, H Yu, N Henderson, S Sarowar, G Zhao, GT Werneburg, ...
Nature 562 (7727), 444-447, 2018
232018
Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
Z Yuan, B Yin, D Wei, YA Yuan
Journal of structural biology 182 (2), 125-135, 2013
232013
Architecture of the Saccharomyces cerevisiae Replisome
L Bai, Z Yuan, J Sun, R Georgescu, ME O’Donnell, H Li
DNA replication: From old principles to new discoveries, 207-228, 2017
182017
The eukaryotic CMG helicase pumpjack and integration into the replisome
J Sun, Z Yuan, R Georgescu, H Li, M O'Donnell
Nucleus 7 (2), 146-154, 2016
162016
Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis
M Du, Z Yuan, GT Werneburg, NS Henderson, H Chauhan, A Kovach, ...
Nature Communications 12 (1), 5207, 2021
102021
Molecular mechanisms of eukaryotic origin initiation, replication fork progression, and chromatin maintenance
Z Yuan, H Li
Biochemical Journal 477 (18), 3499-3525, 2020
102020
Circulating APP, NCAM and Aβ serve as biomarkers for Alzheimer’s disease
K Chen, T Gao, Z Bai, Z Yuan
Brain Research 1699, 117-120, 2018
102018
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Articles 1–20