| Conformational analysis of (+)-germacrene A by variable-temperature NMR and NOE spectroscopy JA Faraldos, S Wu, J Chappell, RM Coates Tetrahedron 63 (32), 7733-7742, 2007 | 92 | 2007 |
| Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency JX Li, X Fang, Q Zhao, JX Ruan, CQ Yang, LJ Wang, DJ Miller, ... Biochemical Journal 451 (3), 417-426, 2013 | 87 | 2013 |
| X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis EY Shishova, F Yu, DJ Miller, JA Faraldos, Y Zhao, RM Coates, ... Journal of biological chemistry 283 (22), 15431-15439, 2008 | 87 | 2008 |
| Probing eudesmane cation− π interactions in catalysis by aristolochene synthase with non-canonical amino acids JA Faraldos, AK Antonczak, V González, R Fullerton, EM Tippmann, ... Journal of the American Chemical Society 133 (35), 13906-13909, 2011 | 82 | 2011 |
| Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase M Chen, N Al-Lami, M Janvier, EL D’Antonio, JA Faraldos, DE Cane, ... Biochemistry 52 (32), 5441-5453, 2013 | 74 | 2013 |
| Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates JP Noel, N Dellas, JA Faraldos, M Zhao, BA Hess Jr, L Smentek, ... ACS Chemical Biology 5 (4), 377-392, 2010 | 73 | 2010 |
| A 1, 6-ring closure mechanism for (+)-δ-cadinene synthase? JA Faraldos, DJ Miller, V Gonzalez, Z Yoosuf-Aly, O Cascón, A Li, ... Journal of the American Chemical Society 134 (13), 5900-5908, 2012 | 71 | 2012 |
| NOVEL STEROLS OF THE TOXIC DINOFLAGELLATE KARENIA BREVIS (DINOPHYCEAE): A DEFENSIVE FUNCTION FOR UNUSUAL MARINE STEROLS?1 JL Giner, JA Faraldos, GL Boyer Journal of phycology 39 (2), 315-319, 2003 | 67 | 2003 |
| Doubly Deuterium-Labeled Patchouli Alcohol from Cyclization of Singly Labeled [2-2H1]Farnesyl Diphosphate Catalyzed by Recombinant Patchoulol Synthase JA Faraldos, S Wu, J Chappell, RM Coates Journal of the American Chemical Society 132 (9), 2998-3008, 2010 | 65 | 2010 |
| Emergence of terpene cyclization in Artemisia annua M Salmon, C Laurendon, M Vardakou, J Cheema, M Defernez, S Green, ... Nature communications 6 (1), 6143, 2015 | 61 | 2015 |
| An efficient chemoenzymatic synthesis of dihydroartemisinic aldehyde M Demiray, X Tang, T Wirth, JA Faraldos, RK Allemann Angewandte Chemie International Edition 56 (15), 4347-4350, 2017 | 58 | 2017 |
| Chemoenzymatic preparation of germacrene analogues O Cascón, S Touchet, DJ Miller, V Gonzalez, JA Faraldos, RK Allemann Chemical communications 48 (78), 9702-9704, 2012 | 56 | 2012 |
| Comparative analysis and validation of the malachite green assay for the high throughput biochemical characterization of terpene synthases M Vardakou, M Salmon, JA Faraldos, PE O’Maille MethodsX 1, 187-196, 2014 | 55 | 2014 |
| Interception of the Enzymatic Conversion of Farnesyl Diphosphate to 5‐Epi‐Aristolochene by Using a Fluoro Substrate Analogue: 1‐Fluorogermacrene A from (2E, 6Z)‐6 … JA Faraldos, Y Zhao, PE O'Maille, JP Noel, RM Coates ChemBioChem 8 (15), 1826-1833, 2007 | 51 | 2007 |
| Evolutionary and mechanistic insights from the reconstruction of α-humulene synthases from a modern (+)-germacrene A synthase V Gonzalez, S Touchet, DJ Grundy, JA Faraldos, RK Allemann Journal of the American Chemical Society 136 (41), 14505-14512, 2014 | 45 | 2014 |
| Bisabolyl-Derived Sesquiterpenes from Tobacco 5-Epi-aristolochene Synthase-Catalyzed Cyclization of (2Z,6E)-Farnesyl Diphosphate JA Faraldos, PE O’Maille, N Dellas, JP Noel, RM Coates Journal of the American Chemical Society 132 (12), 4281-4289, 2010 | 41 | 2010 |
| Intermediacy of eudesmane cation during catalysis by aristolochene synthase JA Faraldos, B Kariuki, RK Allemann The Journal of Organic Chemistry 75 (4), 1119-1125, 2010 | 34 | 2010 |
| Discovery of germacrene A synthases in Barnadesia spinosa: The first committed step in sesquiterpene lactone biosynthesis in the basal member of the Asteraceae TD Nguyen, JA Faraldos, M Vardakou, M Salmon, PE O'Maille, DK Ro Biochemical and biophysical research communications 479 (4), 622-627, 2016 | 30 | 2016 |
| Inhibition of (+)-aristolochene synthase with iminium salts resembling eudesmane cation JA Faraldos, RK Allemann Organic Letters 13 (5), 1202-1205, 2011 | 27 | 2011 |
| A biomimetic approach to the synthesis of an antiviral marine steroidal orthoester JL Giner, JA Faraldos The Journal of Organic Chemistry 67 (8), 2717-2720, 2002 | 27 | 2002 |
Joseph P. NoelProfessor - The Salk Institute for Biological StudiesAdresă de e-mail confirmată pe salk.edu
