| Transformation of hematopoietic cells by BCR/ABL requires activation of a PI‐3k/Akt‐dependent pathway T Skorski, A Bellacosa, M Nieborowska‐Skorska, M Majewski, R Martinez, ... The EMBO journal, 1997 | 821 | 1997 |
| The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein P Neviani, R Santhanam, R Trotta, M Notari, BW Blaser, S Liu, H Mao, ... Cancer cell 8 (5), 355-368, 2005 | 595 | 2005 |
| FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia P Neviani, R Santhanam, JJ Oaks, AM Eiring, M Notari, BW Blaser, S Liu, ... The Journal of clinical investigation 117 (9), 2408-2421, 2007 | 429 | 2007 |
| BCR-ABL suppresses C/EBPα expression through inhibitory action of hnRNP E2 D Perrotti, V Cesi, R Trotta, C Guerzoni, G Santilli, K Campbell, A Iervolino, ... Nature genetics 30 (1), 48-58, 2002 | 400 | 2002 |
| Src homology 2 domain–containing inositol-5-phosphatase and CCAAT enhancer-binding protein β are targeted by miR-155 in B cells of Eμ-MiR-155 transgenic … S Costinean, SK Sandhu, IM Pedersen, E Tili, R Trotta, D Perrotti, ... Blood, The Journal of the American Society of Hematology 114 (7), 1374-1382, 2009 | 361 | 2009 |
| Pro-and antiinflammatory cytokine signaling: reciprocal antagonism regulates interferon-gamma production by human natural killer cells J Yu, M Wei, B Becknell, R Trotta, S Liu, Z Boyd, MS Jaung, BW Blaser, ... Immunity 24 (5), 575-590, 2006 | 300 | 2006 |
| CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets J Yu, HC Mao, M Wei, T Hughes, J Zhang, I Park, S Liu, S McClory, ... Blood, The Journal of the American Society of Hematology 115 (2), 274-281, 2010 | 295 | 2010 |
| TGF-β utilizes SMAD3 to inhibit CD16-mediated IFN-γ production and antibody-dependent cellular cytotoxicity in human NK cells R Trotta, JD Col, J Yu, D Ciarlariello, B Thomas, X Zhang, J Allard, M Wei, ... The Journal of Immunology 181 (6), 3784-3792, 2008 | 277 | 2008 |
| BCR/ABL activates mdm2 mRNA translation via the La antigen R Trotta, T Vignudelli, O Candini, RV Intine, L Pecorari, C Guerzoni, ... Cancer cell 3 (2), 145-160, 2003 | 272 | 2003 |
| miR-155 regulates IFN-γ production in natural killer cells R Trotta, L Chen, D Ciarlariello, S Josyula, C Mao, S Costinean, L Yu, ... Blood, The Journal of the American Society of Hematology 119 (15), 3478-3485, 2012 | 233 | 2012 |
| Triggering of human monocyte activation through CD69, a member of the natural killer cell gene complex family of signal transducing receptors. R De Maria, MG Cifone, R Trotta, MR Rippo, C Festuccia, A Santoni, ... The Journal of experimental medicine 180 (5), 1999-2004, 1994 | 229 | 1994 |
| Activation of mitochondrial Raf-1 is involved in the antiapoptotic effects of Akt M Majewski, M Nieborowska-Skorska, P Salomoni, A Slupianek, K Reiss, ... Cancer research 59 (12), 2815-2819, 1999 | 179 | 1999 |
| TLS/FUS, a pro‐oncogene involved in multiple chromosomal translocations, is a novel regulator of BCR/ABL‐mediated leukemogenesis D Perrotti, S Bonatti, R Trotta, R Martinez, T Skorski, P Salomoni, ... The EMBO journal, 1998 | 175 | 1998 |
| CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain–engineered monoclonal antibody FT Awan, R Lapalombella, R Trotta, JP Butchar, B Yu, DM Benson Jr, ... Blood, The Journal of the American Society of Hematology 115 (6), 1204-1213, 2010 | 149 | 2010 |
| hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis A Iervolino, G Santilli, R Trotta, C Guerzoni, V Cesi, A Bergamaschi, ... Molecular and cellular biology 22 (7), 2255-2266, 2002 | 148 | 2002 |
| Dependence of both spontaneous and antibody-dependent, granule exocytosis-mediated NK cell cytotoxicity on extracellular signal-regulated kinases R Trotta, KA Puorro, M Paroli, L Azzoni, B Abebe, LC Eisenlohr, ... The Journal of Immunology 161 (12), 6648-6656, 1998 | 139 | 1998 |
| High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2–dependent suppression of C/EBPα-driven myeloid differentiation JS Chang, R Santhanam, R Trotta, P Neviani, AM Eiring, E Briercheck, ... Blood, The Journal of the American Society of Hematology 110 (3), 994-1003, 2007 | 128 | 2007 |
| Comparative assessment of clinically utilized CD20-directed antibodies in chronic lymphocytic leukemia cells reveals divergent NK cell, monocyte, and macrophage properties S Rafiq, JP Butchar, C Cheney, X Mo, R Trotta, M Caligiuri, D Jarjoura, ... The Journal of Immunology 190 (6), 2702-2711, 2013 | 125 | 2013 |
| Fc gamma R-dependent mitogen-activated protein kinase activation in leukocytes: a common signal transduction event necessary for expression of TNF-alpha and early activation genes. R Trotta, P Kanakaraj, B Perussia The Journal of experimental medicine 184 (3), 1027-1035, 1996 | 111 | 1996 |
| The SH3 domain contributes to BCR/ABL-dependent leukemogenesis in vivo: role in adhesion, invasion, and homing T Skorski, M Nieborowska-Skorska, P Wlodarski, M Wasik, R Trotta, ... Blood, The Journal of the American Society of Hematology 91 (2), 406-418, 1998 | 109 | 1998 |
