Overlapping motifs (PTAP and PPEY) within the Ebola virus VP40 protein function independently as late budding domains: involvement of host proteins TSG101 and VPS-4 JM Licata, M Simpson-Holley, NT Wright, Z Han, J Paragas, RN Harty Journal of virology 77 (3), 1812-1819, 2003 | 329 | 2003 |
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell Stem Cell 29 (2), 217-231. e8, 2022 | 173 | 2022 |
S100A1 and calmodulin compete for the same binding site on ryanodine receptor NT Wright, BL Prosser, KM Varney, DB Zimmer, MF Schneider, DJ Weber Journal of Biological Chemistry 283 (39), 26676-26683, 2008 | 137 | 2008 |
S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation-contraction coupling BL Prosser, NT Wright, EO Hernandez-Ochoa, KM Varney, Y Liu, ... Journal of Biological Chemistry 283 (8), 5046-5057, 2008 | 125 | 2008 |
The three-dimensional solution structure of Ca2+-bound S100A1 as determined by NMR spectroscopy NT Wright, KM Varney, KC Ellis, J Markowitz, RK Gitti, DB Zimmer, ... Journal of molecular biology 353 (2), 410-426, 2005 | 120 | 2005 |
S100A1: structure, function, and therapeutic potential NT Wright, BR Cannon, DB Zimmer, DJ Weber Current chemical biology 3 (2), 138-145, 2009 | 107 | 2009 |
Gentle, fast and effective crystal soaking by acoustic dispensing PM Collins, JT Ng, R Talon, K Nekrosiute, T Krojer, A Douangamath, ... Acta Crystallographica Section D: Structural Biology 73 (3), 246-255, 2017 | 103 | 2017 |
Restriction endonuclease inhibitor IPI* of bacteriophage T4: a novel structure for a dedicated target D Rifat, NT Wright, KM Varney, DJ Weber, LW Black Journal of molecular biology 375 (3), 720-734, 2008 | 82 | 2008 |
Structure of giant muscle proteins LC Meyer, NT Wright Frontiers in physiology 4, 368, 2013 | 71 | 2013 |
Comorbidity of Substance Misuse and Mental Illness Collaborative study team. Comorbidity of substance misuse and mental illness in community mental health and substance misuse … T Weaver, P Madden, V Charles, G Stimson, A Renton, P Tyrer, T Barnes, ... Br J Psychiatry 183, 304-313, 2003 | 70 | 2003 |
Vaccinia virus-free recovery of vesicular stomatitis virus RN Harty, ME Brown, FP Hayes, NT Wright, MJ Schnell Journal of molecular microbiology and biotechnology 3 (4), 513-518, 2001 | 56 | 2001 |
Solution structure of S100A1 bound to the CapZ peptide (TRTK12) NT Wright, BR Cannon, PT Wilder, MT Morgan, KM Varney, DB Zimmer, ... Journal of molecular biology 386 (5), 1265-1277, 2009 | 54 | 2009 |
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine … H Achdout, A Aimon, E Bar-David, GM Morris BioRxiv, 2020 | 53 | 2020 |
A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy D Rossi, J Palmio, A Evilä, L Galli, V Barone, TA Caldwell, RA Policke, ... PLoS One 12 (10), e0186642, 2017 | 42 | 2017 |
Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin LYR Hu, MA Ackermann, PA Hecker, BL Prosser, B King, KA O’Connell, ... Science Advances 3 (6), e1603081, 2017 | 37* | 2017 |
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ... BioRxiv, 2020.10. 29.339317, 2020 | 36 | 2020 |
Patient mutations linked to arrhythmogenic cardiomyopathy enhance calpain-mediated desmoplakin degradation R Ng, H Manring, N Papoutsidakis, T Albertelli, N Tsai, CJ See, X Li, ... JCI insight 4 (14), 2019 | 36 | 2019 |
Altered specificity of Hint-W123Q supports a role for Hint inhibition by ASW in avian sex determination KP Parks, H Seidle, N Wright, JB Sperry, P Bieganowski, K Howitz, ... Physiological genomics 20 (1), 12-14, 2004 | 35 | 2004 |
Novel mutations in MYBPC1 are associated with myogenic tremor and mild myopathy J Stavusis, B Lace, J Schäfer, J Geist, I Inashkina, D Kidere, S Pajusalu, ... Annals of neurology 86 (1), 129-142, 2019 | 34 | 2019 |
Suicide prevention public service announcements impact help-seeking attitudes: The message makes a difference B Klimes-Dougan, N Wright, DA Klingbeil Frontiers in psychiatry 7, 204320, 2016 | 34 | 2016 |