Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude JS Brenner, DC Pan, JW Myerson, OA Marcos-Contreras, CH Villa, ... Nature communications 9 (1), 2684, 2018 | 292 | 2018 |
Closure device and method JS Brenner, GA Magee, RF Peh, EI Palmer US Patent 9,232,947, 2016 | 202 | 2016 |
PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E … H Parhiz, VV Shuvaev, N Pardi, M Khoshnejad, RY Kiseleva, JS Brenner, ... Journal of controlled release 291, 106-115, 2018 | 123 | 2018 |
Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier OA Marcos-Contreras, CF Greineder, RY Kiseleva, H Parhiz, LR Walsh, ... Proceedings of the National Academy of Sciences 117 (7), 3405-3414, 2020 | 119 | 2020 |
Nanoparticle properties modulate their attachment and effect on carrier red blood cells DC Pan, JW Myerson, JS Brenner, PN Patel, AC Anselmo, S Mitragotri, ... Scientific Reports 8 (1), 1615, 2018 | 119 | 2018 |
Targeting drug delivery in the vascular system: Focus on endothelium PM Glassman, JW Myerson, LT Ferguson, RY Kiseleva, VV Shuvaev, ... Advanced drug delivery reviews 157, 96-117, 2020 | 81 | 2020 |
Vascular drug delivery using carrier red blood cells: focus on RBC surface loading and pharmacokinetics PM Glassman, CH Villa, A Ukidve, Z Zhao, P Smith, S Mitragotri, ... Pharmaceutics 12 (5), 440, 2020 | 75 | 2020 |
Red blood cell hitchhiking: a novel approach for vascular delivery of nanocarriers JS Brenner, S Mitragotri, VR Muzykantov Annual review of biomedical engineering 23, 225-248, 2021 | 68 | 2021 |
TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size JS Brenner, RE Dolmetsch PloS one 2 (8), e802, 2007 | 66 | 2007 |
Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation JW Myerson, PN Patel, KM Rubey, ME Zamora, MH Zaleski, N Habibi, ... Nature nanotechnology 17 (1), 86-97, 2022 | 64 | 2022 |
Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE) H Parhiz, JS Brenner, PN Patel, TE Papp, H Shahnawaz, Q Li, R Shi, ... Journal of Controlled Release 344, 50-61, 2022 | 57 | 2022 |
Unintended effects of drug carriers: Big issues of small particles H Parhiz, M Khoshnejad, JW Myerson, E Hood, PN Patel, JS Brenner, ... Advanced drug delivery reviews 130, 90-112, 2018 | 57 | 2018 |
Neutrophils promote alveolar epithelial regeneration by enhancing type II pneumocyte proliferation in a model of acid-induced acute lung injury AJ Paris, Y Liu, J Mei, N Dai, L Guo, LA Spruce, KM Hudock, JS Brenner, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (6 …, 2016 | 55 | 2016 |
Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers PM Glassman, ED Hood, LT Ferguson, Z Zhao, DL Siegel, S Mitragotri, ... Advanced drug delivery reviews 178, 113992, 2021 | 53 | 2021 |
Targeted endothelial nanomedicine for common acute pathological conditions VV Shuvaev, JS Brenner, VR Muzykantov Journal of Controlled Release 219, 576-595, 2015 | 50 | 2015 |
Endothelial nanomedicine for the treatment of pulmonary disease JS Brenner, C Greineder, V Shuvaev, V Muzykantov Expert opinion on drug delivery 12 (2), 239-261, 2015 | 48 | 2015 |
Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain OA Marcos-Contreras, JS Brenner, RY Kiseleva, V Zuluaga-Ramirez, ... Journal of controlled release 301, 54-61, 2019 | 40 | 2019 |
Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions JS Brenner, K Bhamidipati, PM Glassman, N Ramakrishnan, D Jiang, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (4), 1495-1506, 2017 | 36 | 2017 |
Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9 M Khoshnejad, JS Brenner, W Motley, H Parhiz, CF Greineder, CH Villa, ... Scientific reports 8 (1), 1760, 2018 | 33 | 2018 |
Nanomedicine to fight infectious disease KM Rubey, JS Brenner Advanced drug delivery reviews 179, 113996, 2021 | 31 | 2021 |