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Eusebio Manchado
Eusebio Manchado
Research Scholar, Memorial Sloan Kettering Cancer Center (MSKCC)
Verified email at cnio.es
Title
Cited by
Cited by
Year
In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system
D Maddalo, E Manchado, CP Concepcion, C Bonetti, JA Vidigal, YC Han, ...
Nature 516 (7531), 423-427, 2014
6022014
Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling
S Weissmueller, E Manchado, M Saborowski, JP Morris IV, E Wagenblast, ...
Cell 157 (2), 382-394, 2014
4402014
Genomic stability and tumour suppression by the APC/C cofactor Cdh1
I García-Higuera, E Manchado, P Dubus, M Cañamero, J Méndez, ...
Nature cell biology 10 (7), 802-811, 2008
3652008
A combinatorial strategy for treating KRAS-mutant lung cancer
E Manchado, S Weissmueller, JP Morris, CC Chen, R Wullenkord, ...
Nature 534 (7609), 647-651, 2016
3352016
Killing cells by targeting mitosis
E Manchado, M Guillamot, M Malumbres
Cell Death & Differentiation 19 (3), 369-377, 2012
2362012
Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α, δ phosphatase
E Manchado, M Guillamot, G de Cárcer, M Eguren, M Trickey, ...
Cancer cell 18 (6), 641-654, 2010
2112010
NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination
M Ruscetti, J Leibold, MJ Bott, M Fennell, A Kulick, NR Salgado, CC Chen, ...
Science 362 (6421), 1416-1422, 2018
1872018
Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer
KP O'Rourke, E Loizou, G Livshits, EM Schatoff, T Baslan, E Manchado, ...
Nature biotechnology 35 (6), 577-582, 2017
1762017
The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and-independent functions
E Manchado, M Eguren, M Malumbres
Biochemical Society Transactions 38 (1), 65-71, 2010
1322010
Kinase Regulation of Human MHC Class I Molecule Expression on Cancer CellsKinase Regulation of MHC-I in Tumors
EJ Brea, CY Oh, E Manchado, S Budhu, RS Gejman, G Mo, P Mondello, ...
Cancer immunology research 4 (11), 936-947, 2016
1122016
Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer
M Álvarez-Fernández, M Sanz-Flores, B Sanz-Castillo, M Salazar-Roa, ...
Cell Death & Differentiation, 1-13, 2017
722017
Non-mitotic functions of the Anaphase-Promoting Complex
M Eguren, E Manchado, M Malumbres
Seminars in cell & developmental biology 22 (6), 572-578, 2011
702011
Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice
LE Dow, Z Nasr, M Saborowski, SH Ebbesen, E Manchado, N Tasdemir, ...
PloS one 9 (4), e95236, 2014
672014
SHP2 inhibition overcomes RTK-mediated pathway reactivation in KRAS-mutant tumors treated with MEK inhibitors
H Lu, C Liu, R Velazquez, H Wang, LM Dunkl, M Kazic-Legueux, ...
Molecular cancer therapeutics 18 (7), 1323-1334, 2019
572019
The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors
M Eguren, E Porlan, E Manchado, I García-Higuera, M Cañamero, ...
Nature communications 4 (1), 1-16, 2013
462013
Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription
M Guillamot, E Manchado, M Chiesa, G Gómez-López, DG Pisano, ...
Scientific reports 1 (1), 1-7, 2011
462011
USP39 deubiquitinase is essential for KRAS oncogene-driven cancer
JM Fraile, E Manchado, A Lujambio, V Quesada, D Campos-Iglesias, ...
Journal of Biological Chemistry 292 (10), 4164-4175, 2017
322017
Targeting aneuploidy for cancer therapy
E Manchado, M Malumbres
Cell 144 (4), 465-466, 2011
272011
4th, Wagenblast E, Davis CA, Moon SH, Pfister NT, Tschaharganeh DF, Kitzing T, Aust D, Markert EK, Wu J, et al. Mutant p53 drives pancreatic cancer metastasis through cell …
S Weissmueller, E Manchado, M Saborowski, JP Morris
Cell 157, 382-94, 2014
212014
A pipeline for drug target identification and validation
E Manchado, CH Huang, N Tasdemir, DF Tschaharganeh, JE Wilkinson, ...
Cold Spring Harbor symposia on quantitative biology 81, 257-267, 2016
122016
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