The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth MA Jordan, K Kamath, T Manna, T Okouneva, HP Miller, C Davis, ... Molecular cancer therapeutics 4 (7), 1086-1095, 2005 | 566 | 2005 |
Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint MVS Sivaram, TL Wadzinski, SD Redick, T Manna, SJ Doxsey The EMBO journal 28 (7), 902-914, 2009 | 103 | 2009 |
Regulation of microtubule dynamic instability in vitro by differentially phosphorylated stathmin T Manna, DA Thrower, S Honnappa, MO Steinmetz, L Wilson Journal of biological chemistry 284 (23), 15640-15649, 2009 | 102 | 2009 |
Suppression of microtubule dynamic instability by the+ TIP protein EB1 and its modulation by the CAP-Gly domain of p150glued T Manna, S Honnappa, MO Steinmetz, L Wilson Biochemistry 47 (2), 779-786, 2008 | 102 | 2008 |
Antimitotic sulfonamides inhibit microtubule assembly dynamics and cancer cell proliferation R Mohan, M Banerjee, A Ray, T Manna, L Wilson, T Owa, ... Biochemistry 45 (17), 5440-5449, 2006 | 102 | 2006 |
Chaperone-like activity of tubulin S Guha, TK Manna, KP Das, B Bhattacharyya Journal of Biological Chemistry 273 (46), 30077-30080, 1998 | 81 | 1998 |
Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (formerly ILX651) and its major metabolite tasidotin C-carboxylate A Ray, T Okouneva, T Manna, HP Miller, S Schmid, L Arthaud, R Luduena, ... Cancer Research 67 (8), 3767-3776, 2007 | 78 | 2007 |
Stathmin strongly increases the minus end catastrophe frequency and induces rapid treadmilling of bovine brain microtubules at steady state in vitro T Manna, D Thrower, HP Miller, P Curmi, L Wilson Journal of Biological Chemistry 281 (4), 2071-2078, 2006 | 77 | 2006 |
Chaperone-like activity of tubulin: binding and reactivation of unfolded substrate enzymes T Manna, T Sarkar, A Poddar, M Roychowdhury, KP Das, B Bhattacharyya Journal of Biological Chemistry 276 (43), 39742-39747, 2001 | 63 | 2001 |
Stathmin family protein SCG10 differentially regulates the plus and minus end dynamics of microtubules at steady state in vitro: implications for its role in neurite outgrowth T Manna, G Grenningloh, HP Miller, L Wilson Biochemistry 46 (11), 3543-3552, 2007 | 48 | 2007 |
Sulfhydryls of tubulin: A probe to detect conformational changes of tubulin M Roychowdhury, N Sarkar, T Manna, S Bhattacharyya, T Sarkar, ... European journal of biochemistry 267 (12), 3469-3476, 2000 | 48 | 2000 |
TACC3 protein regulates microtubule nucleation by affecting γ-tubulin ring complexes P Singh, GE Thomas, KK Gireesh, TK Manna Journal of Biological Chemistry 289 (46), 31719-31735, 2014 | 38 | 2014 |
EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice GE Thomas, K Bandopadhyay, S Sutradhar, MR Renjith, P Singh, ... Nature communications 7 (1), 11665, 2016 | 35 | 2016 |
Suppression of centrosome protein TACC3 induces G1 arrest and cell death through activation of p38–p53–p21 stress signaling pathway TV Suhail, P Singh, TK Manna European journal of cell biology 94 (2), 90-100, 2015 | 31 | 2015 |
CIL-102 binds to tubulin at colchicine binding site and triggers apoptosis in MCF-7 cells by inducing monopolar and multinucleated cells KK Gireesh, A Rashid, S Chakraborti, D Panda, T Manna Biochemical pharmacology 84 (5), 633-645, 2012 | 30 | 2012 |
Conformational properties of α-tubulin tail peptide: Implications for tail− body interaction D Pal, P Mahapatra, T Manna, P Chakrabarti, B Bhattacharyya, ... Biochemistry 40 (51), 15512-15519, 2001 | 29 | 2001 |
Kinetochore–microtubule interactions in chromosome segregation: lessons from yeast and mammalian cells GE Thomas, MR Renjith, TK Manna Biochemical Journal 474 (21), 3559-3577, 2017 | 21 | 2017 |
MAP2 prevents protein aggregation and facilitates reactivation of unfolded enzymes: Implications for the chaperone‐like activity of MAP2 T Sarkar, G Mitra, S Gupta, T Manna, A Poddar, D Panda, KP Das, ... European journal of biochemistry 271 (8), 1488-1496, 2004 | 18 | 2004 |
+ TIP EB1 downregulates paclitaxel‑induced proliferation inhibition and apoptosis in breast cancer cells through inhibition of paclitaxel binding on microtubules GE Thomas, JS Sreeja, KK Gireesh, H Gupta, TK Manna International journal of oncology 46 (1), 133-146, 2015 | 17 | 2015 |
Aurora A site specific TACC3 phosphorylation regulates astral microtubule assembly by stabilizing γ-tubulin ring complex R Rajeev, P Singh, A Asmita, U Anand, TK Manna BMC molecular and cell biology 20, 1-13, 2019 | 16 | 2019 |