High-level expression of Falcipain-2 in Escherichia coli by codon optimization and auto-induction ES Sarduy, AC Muñoz, SA Trejo, MAC Planes Protein expression and purification 83 (1), 59-69, 2012 | 42 | 2012 |
An immunoenzymatic solid-phase assay for quantitative determination of HIV-1 protease activity OA Gutiérrez, E Salas, Y Hernández, EA Lissi, G Castrillo, O Reyes, ... Analytical biochemistry 307 (1), 18-24, 2002 | 36 | 2002 |
Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes E Salas-Sarduy, LU Landaburu, J Karpiak, KP Madauss, JJ Cazzulo, ... Scientific reports 7 (1), 12073, 2017 | 34 | 2017 |
In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2 LN Alberca, SR Chuguransky, CL Álvarez, A Talevi, E Salas-Sarduy Frontiers in chemistry 7, 534, 2019 | 32 | 2019 |
Synthetic compounds from an in house library as inhibitors of falcipain-2 from Plasmodium falciparum JB Bertoldo, LD Chiaradia-Delatorre, A Mascarello, PC Leal, ... Journal of Enzyme Inhibition and Medicinal Chemistry 30 (2), 299-307, 2015 | 23 | 2015 |
Antiparasitic effect of a fraction enriched in tight-binding protease inhibitors isolated from the Caribbean coral Plexaura homomalla E Salas-Sarduy, A Cabrera-Muñoz, A Cauerhff, Y González-González, ... Experimental parasitology 135 (3), 611-622, 2013 | 19 | 2013 |
The Trypanosoma cruzi Antigen and Epitope Atlas: antibody specificities in Chagas disease patients across the Americas AD Ricci, L Bracco, E Salas-Sarduy, JM Ramsey, MS Nolan, MK Lynn, ... Nature Communications 14, 1850, 2023 | 18 | 2023 |
DNA‐damage inducible protein 1 is a conserved metacaspase substrate that is cleaved and further destabilized in yeast under specific metabolic conditions LA Bouvier, GT Niemirowicz, E Salas‐Sarduy, JJ Cazzulo, VE Alvarez The FEBS Journal 285 (6), 1097-1110, 2018 | 14 | 2018 |
Thiosemicarbazone derivatives: Evaluation as cruzipain inhibitors and molecular modeling study of complexes with cruzain G Jasinski, E Salas-Sarduy, D Vega, L Fabian, MF Martini, AG Moglioni Bioorganic & Medicinal Chemistry 61, 116708, 2022 | 13 | 2022 |
A heterogeneous enzymatic assay for quantification of Plasmepsin II activity and the evaluation of its inhibitors E Salas, A Ramı́rez, A Otero-Bilbao, R Vázquez, O Reyes, J Mendiola, ... Journal of pharmaceutical and biomedical analysis 34 (4), 833-840, 2004 | 13 | 2004 |
Evaluation of quinoxaline compounds as ligands of a site adjacent to S2 (AS2) of cruzain L Fabian, MF Martini, ES Sarduy, DA Estrin, AG Moglioni Bioorganic & Medicinal Chemistry Letters 29 (16), 2197-2202, 2019 | 11 | 2019 |
Identification of (4-(9H-fluoren-9-yl) piperazin-1-yl) methanone derivatives as falcipain 2 inhibitors active against Plasmodium falciparum cultures JE Hernández-González, E Salas-Sarduy, LF Hernández Ramírez, ... Biochimica et Biophysica Acta (BBA) - General Subjects, 2911–2923, 2018 | 10 | 2018 |
Micro y nano-biotecnologías en la detección y caracterización de inhibidores de proteasas de interés biomédico. R García-Fernández, E Salas, A Del Monte, MA del Rivero, Y Guerra, ... Revista Cubana de Física 26 (1), 2009 | 10* | 2009 |
Intensity fading MALDI-TOF mass spectrometry and functional proteomics assignments to identify protease inhibitors in marine invertebrates G Covaleda, SA Trejo, E Salas-Sarduy, MA Del Rivero, MA Chavez, ... Journal of Proteomics 165, 75-92, 2017 | 9 | 2017 |
In silico identification of noncompetitive inhibitors targeting an uncharacterized allosteric site of falcipain-2 JE Hernández González, E Salas-Sarduy, L Hernández Alvarez, ... Journal of Computer-Aided Molecular Design 35, 1067-1079, 2021 | 8 | 2021 |
Identification of tight-binding plasmepsin II and falcipain 2 inhibitors in aqueous extracts of marine invertebrates by the combination of enzymatic and interaction-based assays E Salas-Sarduy, Y Guerra, G Covaleda Cortés, FX Avilés, ... Marine drugs 15 (4), 123, 2017 | 8 | 2017 |
Computer-aided design of bromelain and papain covalent immobilization B Cutiño-Avila, D Gil Pradas, C Aragón Abreu, Y Fernández Marrero, ... Revista Colombiana de Biotecnología 16 (1), 19-28, 2014 | 7 | 2014 |
Design, synthesis and biological evaluation of novel thiosemicarbazones as cruzipain inhibitors G Jasinski, E Salas-Sarduy, D Vega, L Fabian, MF Martini, AG Moglioni European Journal of Medicinal Chemistry 254, 115345, 2023 | 6 | 2023 |
Tetracycline derivatives inhibit plasmodial cysteine protease falcipain-2 through binding to a distal allosteric site JE Hernandez Gonzalez, LN Alberca, Y Masforrol Gonzalez, ... Journal of Chemical Information and Modeling 62 (1), 159-175, 2021 | 5 | 2021 |
Rational design and synthesis of affinity matrices based on proteases immobilized onto cellulose membranes A del Monte-Martínez, J González-Bacerio, B Cutiño-Avila, J Rojas, ... Preparative Biochemistry and Biotechnology 47 (8), 745-753, 2017 | 5 | 2017 |