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Emir Salas Sarduy
Emir Salas Sarduy
Associate Investigator at IIBIO-CONICET, Universidad Nacional de San Martín
Dirección de correo verificada de iib.unsam.edu.ar
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Citado por
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Año
High-level expression of Falcipain-2 in Escherichia coli by codon optimization and auto-induction
ES Sarduy, AC Muñoz, SA Trejo, MAC Planes
Protein expression and purification 83 (1), 59-69, 2012
412012
An immunoenzymatic solid-phase assay for quantitative determination of HIV-1 protease activity
OA Gutiérrez, E Salas, Y Hernández, EA Lissi, G Castrillo, O Reyes, ...
Analytical biochemistry 307 (1), 18-24, 2002
362002
Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes
E Salas-Sarduy, LU Landaburu, J Karpiak, KP Madauss, JJ Cazzulo, ...
Scientific reports 7 (1), 12073, 2017
332017
In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2
LN Alberca, SR Chuguransky, CL Álvarez, A Talevi, E Salas-Sarduy
Frontiers in chemistry 7, 534, 2019
282019
Synthetic compounds from an in house library as inhibitors of falcipain-2 from Plasmodium falciparum
JB Bertoldo, LD Chiaradia-Delatorre, A Mascarello, PC Leal, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 30 (2), 299-307, 2015
222015
Antiparasitic effect of a fraction enriched in tight-binding protease inhibitors isolated from the Caribbean coral Plexaura homomalla
E Salas-Sarduy, A Cabrera-Muñoz, A Cauerhff, Y González-González, ...
Experimental parasitology 135 (3), 611-622, 2013
172013
A heterogeneous enzymatic assay for quantification of Plasmepsin II activity and the evaluation of its inhibitors
E Salas, A Ramı́rez, A Otero-Bilbao, R Vázquez, O Reyes, J Mendiola, ...
Journal of pharmaceutical and biomedical analysis 34 (4), 833-840, 2004
132004
DNA‐damage inducible protein 1 is a conserved metacaspase substrate that is cleaved and further destabilized in yeast under specific metabolic conditions
LA Bouvier, GT Niemirowicz, E Salas‐Sarduy, JJ Cazzulo, VE Alvarez
The FEBS Journal 285 (6), 1097-1110, 2018
122018
Micro y nano-biotecnologías en la detección y caracterización de inhibidores de proteasas de interés biomédico.
R García-Fernández, E Salas, A Del Monte, MA del Rivero, Y Guerra, ...
Revista Cubana de Física 26 (1), 2009
11*2009
Evaluation of quinoxaline compounds as ligands of a site adjacent to S2 (AS2) of cruzain
L Fabian, MF Martini, ES Sarduy, DA Estrin, AG Moglioni
Bioorganic & Medicinal Chemistry Letters 29 (16), 2197-2202, 2019
92019
Computer-aided design of bromelain and papain covalent immobilization
B Cutiño-Avila, D Gil Pradas, C Aragón Abreu, Y Fernández Marrero, ...
Revista colombiana de biotecnología 16 (1), 19-28, 2014
92014
The Trypanosoma cruzi Antigen and Epitope Atlas: antibody specificities in Chagas disease patients across the Americas
AD Ricci, L Bracco, E Salas-Sarduy, JM Ramsey, MS Nolan, MK Lynn, ...
Nature Communications 14, 1850, 2023
82023
Thiosemicarbazone derivatives: Evaluation as cruzipain inhibitors and molecular modeling study of complexes with cruzain
G Jasinski, E Salas-Sarduy, D Vega, L Fabian, MF Martini, AG Moglioni
Bioorganic & Medicinal Chemistry 61, 116708, 2022
82022
Intensity fading MALDI-TOF mass spectrometry and functional proteomics assignments to identify protease inhibitors in marine invertebrates
G Covaleda, SA Trejo, E Salas-Sarduy, MA Del Rivero, MA Chavez, ...
Journal of Proteomics 165, 75-92, 2017
82017
Identification of tight-binding plasmepsin II and falcipain 2 inhibitors in aqueous extracts of marine invertebrates by the combination of enzymatic and interaction-based assays
E Salas-Sarduy, Y Guerra, G Covaleda Cortés, FX Avilés, ...
Marine drugs 15 (4), 123, 2017
82017
Identification of (4-(9H-fluoren-9-yl) piperazin-1-yl) methanone derivatives as falcipain 2 inhibitors active against Plasmodium falciparum cultures
JE Hernández-González, E Salas-Sarduy, LF Hernández Ramírez, ...
Biochimica et Biophysica Acta (BBA) - General Subjects, 2911–2923, 2018
72018
In silico identification of noncompetitive inhibitors targeting an uncharacterized allosteric site of falcipain-2
JE Hernández González, E Salas-Sarduy, L Hernández Alvarez, ...
Journal of Computer-Aided Molecular Design 35, 1067-1079, 2021
62021
Rational design and synthesis of affinity matrices based on proteases immobilized onto cellulose membranes
A del Monte-Martínez, J González-Bacerio, B Cutiño-Avila, J Rojas, ...
Preparative Biochemistry and Biotechnology 47 (8), 745-753, 2017
62017
Inhibidores de proteasas no proteicos aislados de organismos marinos
I Pascual, Y González, M Alonso del Rivero, A Ramírez, E Salas, R García, ...
Rev Biol 19, 12-9, 2005
42005
Tetracycline derivatives inhibit plasmodial cysteine protease falcipain-2 through binding to a distal allosteric site
JE Hernandez Gonzalez, LN Alberca, Y Masforrol Gonzalez, ...
Journal of Chemical Information and Modeling 62 (1), 159-175, 2021
32021
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