| Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas W Xue, L Zender, C Miething, RA Dickins, E Hernando, V Krizhanovsky, ... Nature 445 (7128), 656-660, 2007 | 2839 | 2007 |
| Senescence of activated stellate cells limits liver fibrosis V Krizhanovsky, M Yon, RA Dickins, S Hearn, J Simon, C Miething, H Yee, ... Cell 134 (4), 657-667, 2008 | 2107 | 2008 |
| The genomic landscape of hypodiploid acute lymphoblastic leukemia L Holmfeldt, L Wei, E Diaz-Flores, M Walsh, J Zhang, L Ding, ... Nature genetics 45 (3), 242-252, 2013 | 785 | 2013 |
| Probing tumor phenotypes using stable and regulated synthetic microRNA precursors RA Dickins, MT Hemann, JT Zilfou, DR Simpson, I Ibarra, GJ Hannon, ... Nature genetics 37 (11), 1289-1295, 2005 | 648 | 2005 |
| Restoration of TET2 function blocks aberrant self-renewal and leukemia progression L Cimmino, I Dolgalev, Y Wang, A Yoshimi, GH Martin, J Wang, V Ng, ... Cell 170 (6), 1079-1095. e20, 2017 | 638 | 2017 |
| Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence A Chicas, X Wang, C Zhang, M McCurrach, Z Zhao, O Mert, RA Dickins, ... Cancer cell 17 (4), 376-387, 2010 | 420 | 2010 |
| Role of genomic instability and p53 in AID-induced c-myc–Igh translocations AR Ramiro, M Jankovic, E Callen, S Difilippantonio, HT Chen, ... Nature 440 (7080), 105-109, 2006 | 398 | 2006 |
| A rapid and scalable system for studying gene function in mice using conditional RNA interference PK Premsrirut, LE Dow, SY Kim, M Camiolo, CD Malone, C Miething, ... Cell 145 (1), 145-158, 2011 | 351 | 2011 |
| MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia C Chen, Y Liu, AR Rappaport, T Kitzing, N Schultz, Z Zhao, AS Shroff, ... Cancer cell 25 (5), 652-665, 2014 | 339 | 2014 |
| Functional identification of optimized RNAi triggers using a massively parallel sensor assay C Fellmann, J Zuber, K McJunkin, K Chang, CD Malone, RA Dickins, Q Xu, ... Molecular cell 41 (6), 733-746, 2011 | 268 | 2011 |
| Stage-specific control of early B cell development by the transcription factor Ikaros TA Schwickert, H Tagoh, S Gültekin, A Dakic, E Axelsson, M Minnich, ... Nature immunology 15 (3), 283-293, 2014 | 226 | 2014 |
| Tissue-specific and reversible RNA interference in transgenic mice RA Dickins, K McJunkin, E Hernando, PK Premsrirut, V Krizhanovsky, ... Nature genetics 39 (7), 914-921, 2007 | 222 | 2007 |
| Metabolic gatekeeper function of B-lymphoid transcription factors LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ... Nature 542 (7642), 479-483, 2017 | 211 | 2017 |
| A pipeline for the generation of shRNA transgenic mice LE Dow, PK Premsrirut, J Zuber, C Fellmann, K McJunkin, C Miething, ... Nature protocols 7 (2), 374-393, 2012 | 196 | 2012 |
| Efficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia ML Churchman, J Low, C Qu, EM Paietta, LH Kasper, Y Chang, ... Cancer cell 28 (3), 343-356, 2015 | 190 | 2015 |
| ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence L Ha, T Ichikawa, M Anver, R Dickins, S Lowe, NE Sharpless, ... Proceedings of the National Academy of Sciences 104 (26), 10968-10973, 2007 | 178 | 2007 |
| Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors M Waibel, VS Solomon, DA Knight, RA Ralli, SK Kim, KM Banks, E Vidacs, ... Cell reports 5 (4), 1047-1059, 2013 | 147 | 2013 |
| The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice RA Dickins, IJ Frew, CM House, MK O'Bryan, AJ Holloway, I Haviv, ... Molecular and cellular biology 22 (7), 2294-2303, 2002 | 123 | 2002 |
| edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens Z Dai, JM Sheridan, LJ Gearing, DL Moore, S Su, S Wormald, S Wilcox, ... F1000Research 3, 2014 | 122 | 2014 |
| Generation and Analysis of Siah2 Mutant Mice IJ Frew, VE Hammond, RA Dickins, JMW Quinn, CR Walkley, NA Sims, ... Molecular and cellular biology 23 (24), 9150-9161, 2003 | 122 | 2003 |
Gregory HannonCRUK, Cambridge University, New York Genome Center, Cold Spring Harbor LaboratoryVerified email at cruk.cam.ac.uk
